Xaa-Pro aminopeptidase
Details
- Name
- Xaa-Pro aminopeptidase
- Synonyms
- 3.4.11.9
- Aminoacylproline aminopeptidase
- Aminopeptidase P II
- APP-II
- X-Pro aminopeptidase
- Gene Name
- pepP
- Organism
- Escherichia coli (strain K12)
- Amino acid sequence
>lcl|BSEQ0011168|Xaa-Pro aminopeptidase MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPE AVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQ LLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPE EIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENG CILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLET SLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLD VHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENL TASVVKKPEEIEALMVAARKQ
- Number of residues
- 441
- Molecular Weight
- 49815.05
- Theoretical pI
- 5.07
- GO Classification
- Functionsaminopeptidase activity / manganese ion binding / metallopeptidase activityComponentscytosol
- General Function
- Metallopeptidase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011169|Xaa-Pro aminopeptidase (pepP) ATGAGTGAGATATCCCGGCAAGAGTTTCAGCGTCGCCGTCAGGCCCTGGTGGAGCAAATG CAACCCGGCAGCGCCGCGCTGATTTTTGCTGCACCAGAAGTAACACGTAGCGCCGACAGC GAATACCCCTATCGTCAGAACAGTGACTTCTGGTACTTCACCGGCTTTAACGAACCGGAA GCGGTGCTGGTGCTGATTAAAAGCGATGACACTCATAACCACAGCGTTCTGTTTAACCGC GTTCGCGACCTGACGGCGGAGATCTGGTTTGGCCGTCGCTTAGGCCAGGATGCCGCGCCA GAGAAACTGGGCGTTGACCGCGCACTGGCATTCAGCGAAATCAATCAGCAACTTTATCAA CTACTTAACGGCCTGGATGTGGTTTACCATGCCCAGGGCGAATATGCATATGCTGATGTA ATCGTGAACAGTGCGCTGGAAAAACTGCGTAAAGGTTCGCGGCAAAATCTCACCGCACCG GCAACGATGATCGACTGGCGTCCTGTTGTTCATGAAATGCGCCTGTTCAAATCGCCAGAA GAGATTGCCGTACTCCGCCGCGCGGGAGAAATCACCGCCATGGCACATACACGGGCGATG GAAAAATGCCGTCCGGGAATGTTCGAGTACCATCTGGAAGGCGAAATTCACCACGAATTT AACCGCCACGGTGCGCGCTATCCGTCCTATAACACCATTGTCGGCAGCGGTGAAAACGGC TGCATTCTGCACTACACCGAAAACGAGTGTGAAATGCGCGACGGCGACCTGGTGTTGATT GACGCGGGTTGTGAATACAAAGGTTACGCTGGCGATATTACCCGCACCTTCCCGGTCAAC GGCAAATTCACCCAGGCCCAGCGTGAAATCTACGACATTGTGCTGGAGTCTCTCGAAACC AGCCTGCGCCTGTATCGTCCGGGAACTTCCATTCTGGAAGTCACTGGTGAAGTGGTGCGC ATCATGGTTAGCGGCCTGGTAAAACTCGGCATCCTGAAAGGTGATGTTGATGAACTGATC GCTCAGAACGCCCATCGTCCTTTCTTTATGCATGGCCTTAGCCACTGGTTAGGACTGGAT GTCCATGACGTGGGTGTTTATGGTCAGGATCGCTCGCGCATTCTGGAACCGGGCATGGTA CTGACCGTAGAGCCAGGGCTGTATATTGCGCCGGATGCAGAAGTGCCAGAACAATATCGC GGTATCGGCATTCGTATTGAAGACGACATTGTGATTACCGAAACCGGTAACGAAAACCTC ACCGCCAGCGTGGTGAAAAAGCCGGAAGAAATCGAAGCGTTGATGGTTGCTGCGAGAAAG CAATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P15034 UniProtKB Entry Name AMPP_ECOLI GenBank Protein ID 216529 GenBank Gene ID D00398 - General References
- Yoshimoto T, Tone H, Honda T, Osatomi K, Kobayashi R, Tsuru D: Sequencing and high expression of aminopeptidase P gene from Escherichia coli HB101. J Biochem. 1989 Mar;105(3):412-6. [Article]
- Nakahigashi K, Miyamoto K, Nishimura K, Inokuchi H: Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone. J Bacteriol. 1992 Nov;174(22):7352-9. [Article]
- Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. [Article]
- Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T: Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol. 2006;2:2006.0007. Epub 2006 Feb 21. [Article]
- Wilce MC, Bond CS, Dixon NE, Freeman HC, Guss JM, Lilley PE, Wilce JA: Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3472-7. [Article]