V-type proton ATPase subunit C 1
Details
- Name
- V-type proton ATPase subunit C 1
- Synonyms
- ATP6C
- ATP6D
- V-ATPase subunit C 1
- Vacuolar proton pump subunit C 1
- VATC
- Gene Name
- ATP6V1C1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0017461|V-type proton ATPase subunit C 1 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAK LDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKN ISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSE YLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHK ARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKAL RVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLN LSQQEYYPYVYYKIDCNLLEFK
- Number of residues
- 382
- Molecular Weight
- 43941.245
- Theoretical pI
- Not Available
- GO Classification
- Functionshydrogen-exporting ATPase activity, phosphorylative mechanism / proton-transporting ATPase activity, rotational mechanism / transporter activityProcessesATP hydrolysis coupled proton transport / cellular iron ion homeostasis / insulin receptor signaling pathway / ion transmembrane transport / phagosome maturation / proton transport / transferrin transport / transmembrane transportComponentsapical part of cell / cytoplasmic vesicle / cytosol / extracellular exosome / lysosomal membrane / plasma membrane / proton-transporting two-sector ATPase complex / proton-transporting V-type ATPase, V1 domain
- General Function
- Transporter activity
- Specific Function
- Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
- Pfam Domain Function
- V-ATPase_C (PF03223)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0017462|V-type proton ATPase subunit C 1 (ATP6V1C1) ATGACTGAGTTCTGGCTTATATCTGCTCCTGGGGAGAAAACCTGTCAGCAAACATGGGAG AAATTGCATGCGGCAACTTCAAAGAACAATAATCTTGCTGTCACTTCCAAGTTCAATATT CCTGACTTAAAGGTTGGCACGTTGGATGTCTTGGTTGGCTTGTCAGATGAACTGGCTAAA CTGGATGCATTTGTAGAAGGAGTGGTTAAGAAAGTAGCTCAATACATGGCTGATGTATTG GAAGATAGCAAAGACAAAGTTCAAGAGAATCTGTTGGCTAATGGAGTGGACTTGGTTACT TATATAACAAGGTTCCAGTGGGACATGGCCAAATATCCAATCAAGCAGTCCCTGAAAAAT ATTTCTGAAATAATTGCCAAGGGAGTAACTCAGATTGATAATGACCTGAAATCTCGAGCA TCTGCATACAATAACCTGAAAGGAAATCTTCAGAATTTGGAACGAAAGAATGCAGGAAGT TTGCTAACTAGAAGTCTAGCAGAAATTGTGAAGAAGGATGACTTTGTTCTTGATTCAGAG TATCTCGTCACATTACTGGTAGTAGTTCCCAAGTTAAACCACAACGACTGGATTAAGCAG TATGAAACACTAGCCGAAATGGTAGTTCCAAGGTCTAGCAATGTTCTTTCAGAGGACCAA GACAGTTACCTGTGTAATGTCACCTTGTTTAGGAAGGCAGTTGATGACTTCAGACACAAA GCCAGAGAAAACAAATTCATTGTTCGTGACTTCCAGTATAATGAAGAGGAGATGAAAGCA GATAAAGAAGAAATGAACAGGCTTTCTACTGATAAGAAAAAACAATTTGGACCACTTGTA CGGTGGCTGAAAGTGAATTTTAGTGAAGCATTTATTGCATGGATTCACGTGAAAGCATTA CGGGTTTTCGTTGAGTCTGTTTTAAGGTATGGCTTGCCAGTGAACTTCCAAGCAATGCTA CTTCAGCCCAATAAGAAAACTTTGAAGAAACTGAGAGAAGTATTACATGAATTGTATAAA CATCTAGACAGCAGTGCAGCAGCTATTATTGATGCTCCTATGGATATTCCAGGTTTAAAC CTGAGTCAACAAGAATACTACCCCTATGTGTACTACAAGATTGATTGCAACTTGCTGGAA TTCAAGTGA
- Chromosome Location
- 8
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P21283 UniProtKB Entry Name VATC1_HUMAN HGNC ID HGNC:856 - General References
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