3-ketoacyl-CoA thiolase
Details
- Name
- 3-ketoacyl-CoA thiolase
- Synonyms
- 2.3.1.16
- Acetyl-CoA acyltransferase
- Beta-ketothiolase
- faoB
- Fatty acid oxidation complex subunit beta
- Gene Name
- fadA
- Organism
- Pseudomonas fragi
- Amino acid sequence
>lcl|BSEQ0017385|3-ketoacyl-CoA thiolase MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWG CVNQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVG GVEHMGHVSMMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGISREQQDAFAVRSHQLA HKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKGGTVTAG TSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRAG LNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTL LNVMKQNGGTFGLSTMCIGLGQGIATVFERV
- Number of residues
- 391
- Molecular Weight
- 41605.72
- Theoretical pI
- 7.0
- GO Classification
- Functionsacetyl-CoA C-acyltransferase activityProcessesfatty acid beta-oxidationComponentscytoplasm
- General Function
- Acetyl-coa c-acyltransferase activity
- Specific Function
- Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0008093|2148 bp ATGATTTACGAAGGTAAAGCCATCACGGTTACGGCTCTTGAAAGTGGCATCGTCGAACTG AAGTTCGACCTCAAGGGTGAGTCCGTCAACAAATTCAACCGTCTAACCCTGAACGAATTG CGTCAGGCGGTAGATGCGATCAAGGCCGACGCTTCGGTCAAGGGTGTCATCGTTTCCAGC GGTAAAGACGTATTTATCGTCGGCGCCGACATCACCGAATTCGTCGAAAACTTCAAGTTG CCGGATGCCGAGCTGATTGCTGGCAACCTCGAAGCCAACAAGATCTTCAGCGATTTTGAA GACCTCAATGTACCCACCGTCGCAGCCATCAATGGCATCGCGTTGGGCGGTGGCCTGGAA ATGTGCCTGGCAGCCGACTTCCGGGTCATGGCCGACAGCGCCAAGATCGGCCTGCCGGAA GTCAAACTGGGCATCTACCCGGGCTTTGGCGGCACCGTACGTCTGCCACGCCTGATCGGT GTTGATAACGCGGTTGAGTGGATTGCCTCCGGCAAGGAAAACCGCGCAGAAGACGCTCTG AAAGTCAGCGCCGTTGATGCTGTTGTCACTGCTGACAAGCTGGGCGCAGCTGCCCTGGAC CTGATCAAGCGCGCCATCAGTGGCGAACTGGACTACAAGGCCAAGCGTCAGCCGAAGCTG GAAAAACTCAAGCTCAACGCTATCGAACAAATGATGGCTTTCGAAACCGCCAAAGGTTTC GTGGCTGGCCAGGCCGGCCCGAACTACCCGGCCCCGGTTGAAGCGATCAAGACCATCCAG AAAGCCGCGAACTTCGGTCGTGACAAAGCCCTGGAAGTGGAAGCTGCAGGTTTCGCCAAG CTGGCCAAAACCAGCGCCTCGAACTGCCTGATCGGCCTGTTCCTGAACGATCAGGAACTG AAGAAAAAGGCCAAGGTCTACGACAAGATCGCCAAAGACGTGAAGCAGGCCGCCGTTCTG GGCGCCGGCATCATGGGTGGCGGCATTGCCTATCAGTCGGCGTCCAAAGGCACGCCGATC CTGATGAAGGACATCAACGAGCACGGTATCGAGCAGGGCCTGGCTGAAGCCGCCAAGCTG CTGGTAGGTCGCGTTGATAAAGGTCGCATGACCCCGGCAAAAATGGCTGAAGTGCTGAAC GGCATTCGTCCTACTCTGTCCTACGGCGATTTCGGCAACGTCGACCTGGTGGTCGAAGCG GTTGTCGAGAACCCGAAGGTCAAGCAGGCCGTGTTGGCGGAAGTGGAAAACCACGTTCGC GAAGACGCCATCCTCGCTTCCAACACCTCGACCATTTCCATCAGCTTGCTGGCCAAGGCC CTCAAGCGTCCGGAAAACTTCGTCGGCATGCACTTCTTCAACCCGGTACACATGATGCCG CTGGTTGAAGTGATCCGTGGCGAGAAGTCCAGCGACCTGGCCGTGGCCACCACCGTTGCC TACGCCAAGAAAATGGGCAAGAACCCGATCGTGGTCAACGACTGCCCGGGCTTCCTGGTC AACCGCGTACTGTTCCCGTACTTCGGCGGTTTCGCCAAGCTGGTCAGCGCCGGTGTCGAC TTTGTGCGTATCGACAAAGTGATGGAAAAATTCGGCTGGCCGATGGGCCCGGCGTACCTG ATGGACGTGGTCGGTATCGACACTGGCCACCACGGTCGCGACGTGATGGCTGAAGGCTTC CCGGACCGCATGAAAGACGACCGCCGCTCGGCGATCGATGCGCTGTACGAGGCCAAGCGC CTGGGTCAGAAGAACGGCAAGGGCTTCTACGCCTACGAGGCTGACAAAAAGGGCAAGCAG AAGAAACTGGTTGATTCGAGCGTGCTTGAAGTGCTCAAACCAATCGTTTACGAGCAGCGC GACGTGACCGACGAAGACATCATCAACTGGATGATGATCCCGCTGTGCCTGGAAACCGTG CGTTGCCTGGAAGACGGTATCGTTGAAACTGCAGCCGAGGCCGATATGGGCCTGGTCTAC GGCATTGGCTTCCCGCTGTTCCGTGGTGGCGCGCTGCGCTACATCGATTCGATCGGTGTT GCAGAGTTCGTCGCCCTGGCCGATCAGTACGCTGAACTGGGCGCGCTGTACCACCCGACT GCGAAGCTGCGTGAGATGGCCAAGAACGGCCAGAGCTTCTTCGGTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P28790 UniProtKB Entry Name FADA_PSEFR GenBank Protein ID 391839 GenBank Gene ID D10390 - General References
- Sato S, Hayashi M, Imamura S, Ozeki Y, Kawaguchi A: Primary structures of the genes, faoA and faoB, from Pseudomonas fragi B-0771 which encode the two subunits of the HDT multienzyme complex involved in fatty acid beta-oxidation. J Biochem. 1992 Jan;111(1):8-15. [Article]