Genome polyprotein
Details
- Name
- Genome polyprotein
- Synonyms
- 3.4.22.29
- P2A
- Gene Name
- Not Available
- Organism
- Echovirus 11 (strain Gregory)
- Amino acid sequence
>lcl|BSEQ0012952|Genome polyprotein MGAQVSTQKTGAHETGLNASGSSIIHYTNINYYKDAASNSANRQEFSQDPGKFTEPVKDI MVKSLPALNSPSAEECGYSDRVRSITLGNSTITTQESANVVVGYGRWPEYLKDNEATAED QPTQPDVATCRFYTLESVTWERDSPGWWWKFPDALKDMGLFGQNMYYHYLGRAGYTLHVQ CNASKFHQGCLLVVCVPEAEMGCSQVDGTVNEHGLSEGETAKKFSSTSTNGTNTVQTIVT NAGMGVGVGNLTIYPHQWINLRTNNCATIVMPYINNVPMDNMFRHHNFTLMIIPFVPLDY SSDSSTYVPITVTVAPMCAEYNGLRLSTSLQGLPVMNTPGSNQFLTSDDFQSPSAMPQFD VTPELNIPGEVQNLMEIAEVDSVVPVNNVEGKLDTMEVYRIPVQSGNHQSDQVFGFQVQP GLDSVFKHTLLGEILNYFAHWSGSIKLTFVFCGSAMATGKFLLAYAPPGANAPKNRKDAM LGTHIIWDVGLQSSCVLCVPWISQTHYRLVQQDEYTSAGNVTCWYQTGIVVPAGTPTSCS IMCFVSACNDFSVRLLKDTPFIEQTALLQGDVVEAVENAVARVADTIGSGPSNSQAVPAL TAVETGHTSQVTPSDTMQTRHVKNYHSRSESSIENFLSRSACVYMGGYHTTNTDQTKLFA SWTISARRMVQMRRKLEIFTYVRFDVEVTFVITSKQDQGSRLGQDMPPLTHQIMYIPPGG PIPKSVTDYAWQTSTNPSIFWTEGNAPPRMSIPFISIGNAYSNFYDGWSHFSQNGVYGYN TLNHMGQIYVRHVNGSSPLPMTSTVRMYFKPKHVKAWVPRPPRLCQYKNASTVNFTPTNV TDKRTSINYIPETVKPDLSNYGAFGYQSGAVYVVNYRVVNRHLATHTDWQNCVWEDYNRD LLISTTTAHGCDVIARCRCSTGVYYCQSKGKHYPVNFEGPGLVEVQESEYYPKRYQSHVL LAAGFSEPGDCGGILRCEHGVIGIVTMGGEGVVGFADVRDLLWLEDDAMEQGVKDYVEQL GNAFGSGFTNQICEQVNLLKESLVGQDSILEKSLKALVKIISALVIVVRNHDDLITVTAT LALIGCTSSPWRWLKQKVSQYYGIPMAERQNNGWLKKFTEMTNSCKGMEWISIKIQKFIE WLKVKILPEVREKHEFLNRLKQLPLLESQIATIEQSAPSQSDQEQLFSNVQYFAHYCRKY APLYASEAKRVFSLEKKMSNYIQFKSKCRIEPVCLLLHGSPGAGKSVATNLIGRSLAEKL NSSVYTLPPDPDHFDGYKQQAVVIVDDLCQNPDGKDVSLFCQMVSSVDFVPPMAALEEKG ILFTSLFVLASTNAGSINAPTVSDSRALARRFHFDMNIEVISMYSQNGKINMPMSEKTCD EECCPVNFKRCCPLVCGKAIQFIDRRTQVRYSLDMLVTEMFREYNHRHSVGATLEALFQG PPIYREIKISVAPETPPPPAIADLLKSVDSEAVREYCKEKGWLVPEVNSTLQIEKHVSRA FICLQALTTFVSVAGIIYIIYKLFAGFQGAYTGMPNQKPKVPTLRQAKVQGPAFEFAVAM MKRNSSTVKTEYREFTMLGIYDRWAVLPRHAKPGPTILMNNQEVGVLDAKELVDKDGTNL ELTLLKLNRNEKFRDIRGFLAKEEVEANQAVLAINTSKFPNMYIPVGQVTDYGFLNLGGT PTKRMLMSNFPTRAGQCGGVLMSTGKVLGIHVGGNGHQGFSAALLKHYFNDEQGEIEFIE SSKDAGFPIINTPSKTKLEPSVFHQVFEGDKEPAVLRNGDPRLKANFEEAIFSKYIGNVN THVDEYMLEAVDHYAGQLATLDISTEPMRLEDAVYGTEGLEALDLTTSAGYPYVALGIKK RDILSRRTRDLTKLKECMDKYGLNLPMVTYVKDELRSADKVAKGKSRLIEASSLNDSVAM RQTFGNLYRTFHLNPGIVTGSAVGCDPDLFWSKIPVMLDGHLIAFDYSGYDASLSPVWFA CLKLLLEKLGYTHKETNYIDYLCNSHHLYRDKHYFERGGMPSGYSGTSMFNSMINNIIIR TLMLKVYKGIDLDQFRMIAYGDDVIASYPWPIDASLLAETGKGYGLIMTPADKGECFNEV TWTNVTFLKRYFRADEQYPFLVHPVMPMKDIHESIRWTKDPKNTQDHVRSLCLLAWHNGE HEYEEFIRKIRSVPVGRCLTLPAFSTLRRKWLDSF
- Number of residues
- 2195
- Molecular Weight
- 245405.09
- Theoretical pI
- 6.83
- GO Classification
- FunctionsATP binding / cysteine-type endopeptidase activity / ion channel activity / RNA binding / RNA helicase activity / RNA-directed RNA polymerase activity / structural molecule activityProcessesDNA replication / endocytosis involved in viral entry into host cell / induction by virus of host autophagy / pore formation by virus in membrane of host cell / pore-mediated entry of viral genome into host cell / positive stranded viral RNA replication / protein oligomerization / RNA-protein covalent cross-linking / suppression by virus of host gene expression / suppression by virus of host mRNA export from nucleus / suppression by virus of host RIG-I activity by RIG-I proteolysis / suppression by virus of host translation initiation factor activity / transcription, DNA-templated / viral RNA genome replication / virion attachment to host cellComponentshost cell cytoplasmic vesicle membrane / integral to membrane of host cell / membrane / T=pseudo3 icosahedral viral capsid
- General Function
- Structural molecule activity
- Specific Function
- Capsid protein VP1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host CD55 to provide virion attachment to target host cells. This attachment induces virion internalization. Tyrosine kinases are probably involved in the entry process. After binding to its receptor, the capsid undergoes conformational changes. Capsid protein VP1 N-terminus (that contains an amphipathic alpha-helix) and capsid protein VP4 are externalized. Together, they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been released, the channel shrinks (By similarity).Capsid protein VP2: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome (By similarity).Capsid protein VP3: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome (By similarity).Capsid protein VP4: Lies on the inner surface of the capsid shell. After binding to the host receptor, the capsid undergoes conformational changes. Capsid protein VP4 is released, Capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host membrane through which the viral genome is translocated into the host cell cytoplasm. After genome has been released, the channel shrinks (By similarity).Capsid protein VP0: Component of immature procapsids, which is cleaved into capsid proteins VP4 and VP2 after maturation. Allows the capsid to remain inactive before the maturation step (By similarity).Protein 2A: Cysteine protease that cleaves viral polyprotein and specific host proteins. It is responsible for the cleavage between the P1 and P2 regions, first cleavage occurring in the polyprotein. Cleaves also the host translation initiation factor EIF4G1, in order to shut down the capped cellular mRNA translation. Inhibits the host nucleus-cytoplasm protein and RNA trafficking by cleaving host members of the nuclear pores (By similarity).Protein 2B: Plays an essential role in the virus replication cycle by acting as a viroporin. Creates a pore in the host reticulum endoplasmic and as a consequence releases Ca2+ in the cytoplasm of infected cell. In turn, high levels of cyctoplasmic calcium may trigger membrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication (By similarity).Protein 2C: Induces and associates with structural rearrangements of intracellular membranes. Displays RNA-binding, nucleotide binding and NTPase activities. May play a role in virion morphogenesis and viral RNA encapsidation by interacting with the capsid protein VP3 (By similarity).Protein 3AB: Localizes the viral replication complex to the surface of membranous vesicles. Together with protein 3CD binds the Cis-Active RNA Element (CRE) which is involved in RNA synthesis initiation. Acts as a cofactor to stimulate the activity of 3D polymerase, maybe through a nucleid acid chaperone activity (By similarity).Protein 3A: Localizes the viral replication complex to the surface of membranous vesicles. It inhibits host cell endoplasmic reticulum-to-Golgi apparatus transport and causes the dissassembly of the Golgi complex, possibly through GBF1 interaction. This would result in depletion of MHC, trail receptors and IFN receptors at the host cell surface (By similarity).Viral protein genome-linked: acts as a primer for viral RNA replication and remains covalently bound to viral genomic RNA. VPg is uridylylated prior to priming replication into VPg-pUpU. The oriI viral genomic sequence may act as a template for this. The VPg-pUpU is then used as primer on the genomic RNA poly(A) by the RNA-dependent RNA polymerase to replicate the viral genome. VPg may be removed in the cytoplasm by an unknown enzyme termed "unlinkase". VPg is not cleaved off virion genomes because replicated genomic RNA are encapsidated at the site of replication (By similarity).Protein 3CD: Is involved in the viral replication complex and viral polypeptide maturation. It exhibits protease activity with a specificity and catalytic efficiency that is different from protease 3C. Protein 3CD lacks polymerase activity. The 3C domain in the context of protein 3CD may have an RNA binding activity (By similarity).Protease 3C: cleaves host DDX58/RIG-I and thus contributes to the inhibition of type I interferon production. Cleaves also host PABPC1 (By similarity).RNA-directed RNA polymerase: Replicates the viral genomic RNA on the surface of intracellular membranes. May form linear arrays of subunits that propagate along a strong head-to-tail interaction called interface-I. Covalently attaches UMP to a tyrosine of VPg, which is used to prime RNA synthesis. The positive stranded RNA genome is first replicated at virus induced membranous vesicles, creating a dsRNA genomic replication form. This dsRNA is then used as template to synthesize positive stranded RNA genomes. ss(+)RNA genomes are either translated, replicated or encapsidated (By similarity).
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Virion
- Gene sequence
>lcl|BSEQ0008047|6588 bp ATGGGAGCGCAAGTATCAACACAAAAGACCGGTGCGCATGAAACCGGCTTGAACGCCAGT GGTAGTTCTATAATCCACTACACCAACATAAACTACTATAAAGATGCAGCATCCAACTCG GCAAATAGGCAAGAATTTTCACAAGACCCTGGTAAGTTCACCGAACCAGTGAAGGATATC ATGGTGAAGTCACTACCTGCACTTAACTCGCCGTCTGCTGAAGAGTGTGGGTACAGTGAC AGAGTGCGATCCATAACACTAGGTAACTCTACCATCACAACACAAGAAAGTGCAAATGTA GTAGTGGGGTATGGTCGATGGCCTGAGTACCTGAAAGACAATGAGGCCACTGCTGAAGAT CAACCAACCCAGCCTGATGTAGCAACATGTAGGTTTTACACCCTGGAATCGGTCACGTGG GAAAGAGATTCACCCGGGTGGTGGTGGAAATTCCCGGACGCCCTAAAAGATATGGGGCTC TTCGGCCAAAACATGTACTACCACTATCTAGGAAGAGCCGGTTACACATTGCATGTACAA TGTAATGCATCTAAATTCCATCAGGGATGCTTGCTAGTGGTCTGTGTACCGGAAGCAGAG ATGGGATGCAGCCAAGTGGATGGTACTGTAAATGAGCATGGATTGAGTGAGGGGGAGACC GCTAAGAAATTCTCTTCCACCAGCACAAATGGGACCAACACGGTACAGACGATTGTGACA AATGCCGGTATGGGAGTGGGAGTGGGCAATCTCACTATATACCCACATCAGTGGATAAAT TTGCGCACCAATAACTGCGCCACCATCGTCATGCCATACATAAACAACGTACCGATGGAC AACATGTTCAGACACCACAATTTCACACTAATGATTATTCCCTTTGTACCATTAGACTAT TCTTCAGATTCATCCACGTACGTGCCCATAACAGTGACAGTCGCTCCAATGTGTGCTGAG TATAATGGTTTGAGGCTCTCAACCTCATTGCAAGGATTACCTGTCATGAATACACCGGGT AGCAACCAGTTTCTGACATCGGACGACTTCCAGTCACCATCTGCCATGCCACAATTTGAT GTCACCCCAGAGTTAAATATACCAGGGGAGGTACAAAACCTCATGGAAATTGCTGAAGTC GACTCGGTGGTGCCAGTCAACAACGTGGAAGGGAAACTCGACACAATGGAGGTCTACCGG ATTCCAGTGCAGAGTGGTAATCACCAAAGTGACCAAGTCTTCGGTTTTCAAGTGCAACCT GGGCTAGATAGCGTTTTCAAACACACGCTACTGGGGGAGATTTTGAACTACTTTGCACAC TGGTCTGGTAGTATAAAACTAACATTTGTTTTCTGTGGTTCCGCTATGGCTACGGGTAAA TTCCTACTAGCCTACGCCCCGCCCGGAGCGAACGCTCCTAAGAATAGGAAAGATGCAATG CTGGGCACACACATTATCTGGGATGTTGGACTGCAGTCATCGTGTGTCTTATGTGTGCCT TGGATTAGTCAAACTCACTATAGGTTGGTGCAGCAGGACGAGTACACAAGCGCTGGCAAT GTCACATGCTGGTATCAGACTGGAATAGTCGTCCCGGCGGGCACTCCGACATCGTGCTCC ATCATGTGTTTTGTATCGGCATGCAATGATTTCTCTGTGAGATTACTAAAGGACACGCCA TTTATAGAACAAACTGCATTACTGCAAGGTGATGTGGTAGAAGCTGTAGAGAACGCCGTT GCACGTGTGGCAGATACAATTGGTAGTGGGCCGTCAAATTCGCAAGCAGTGCCTGCTTTA ACAGCAGTTGAGACAGGGCACACATCTCAGGTGACACCCAGTGATACCATGCAAACCAGG CATGTCAAGAACTACCATTCCAGATCTGAGTCCAGCATTGAAAACTTCCTCAGCAGATCT GCCTGCGTTTATATGGGAGGATACCACACAACCAACACTGACCAGACAAAATTATTTGCC TCATGGACTATTAGTGCACGACGCATGGTTCAAATGAGACGCAAGCTAGAGATCTTCACT TACGTCCGTTTTGATGTGGAGGTGACTTTTGTGATTACCAGCAAGCAGGACCAGGGCTCC CGATTGGGCCAAGACATGCCACCCCTGACTCACCAGATCATGTATATCCCACCAGGGGGG CCCATTCCAAAGTCTGTCACTGACTATGCATGGCAAACCTCCACCAACCCCAGCATTTTC TGGACTGAGGGGAACGCGCCACCCAGAATGTCTATCCCATTCATTAGCATTGGTAACGCC TACAGTAATTTTTACGACGGGTGGTCTCACTTCTCGCAAAACGGGGTGTATGGCTACAAC ACACTCAACCACATGGGTCAAATTTATGTTAGACACGTGAATGGATCATCACCACTCCCT ATGACTAGCACTGTTAGAATGTACTTCAAGCCGAAGCATGTTAAAGCATGGGTCCCGCGG CCTCCTAGGCTATGCCAATACAAAAATGCATCCACGGTGAACTTTACACCCACAAACGTC ACCGACAAGCGAACCAGCATCAACTACATTCCTGAGACGGTCAAACCAGACCTATCAAAC TACGGAGCTTTTGGATACCAATCAGGGGCCGTGTACGTCGTAAACTACAGGGTGGTGAAC CGGCATCTGGCAACCCATACCGACTGGCAAAACTGTGTATGGGAGGACTACAACAGAGAC CTCCTTATAAGCACCACCACAGCCCACGGATGCGATGTTATAGCCAGGTGTCGCTGTTCA ACGGGGGTCTACTACTGTCAGTCTAAGGGTAAGCACTACCCAGTCAATTTTGAGGGACCG GGTCTTGTGGAAGTTCAGGAGAGTGAGTACTATCCCAAGAGATATCAATCCCATGTCCTT CTCGCGGCAGGATTTTCCGAGCCTGGCGATTGTGGTGGGATTCTGAGATGCGAGCACGGT GTCATCGGAATTGTGACCATGGGGGGTGAAGGTGTCGTTGGCTTTGCCGACGTGCGTGAC CTCTTGTGGTTGGAGGACGATGCGATGGAGCAGGGAGTGAAGGACTATGTAGAGCAACTT GGAAATGCCTTTGGTTCGGGCTTCACCAACCAAATTTGTGAACAAGTCAACCTCCTAAAA GAGTCACTAGTGGGTCAAGACTCCATCCTAGAGAAGTCTCTGAAAGCTTTGGTGAAAATA ATATCAGCCTTAGTAATTGTGGTGAGAAATCACGATGACTTAATCACAGTAACTGCCACA CTGGCCCTCATCGGCTGCACCTCATCCCCGTGGCGGTGGCTTAAACAGAAGGTATCGCAA TACTATGGGATACCCATGGCTGAACGTCAAAACAACGGGTGGCTCAAGAAGTTCACTGAA ATGACCAATTCTTGTAAGGGTATGGAATGGATATCCATAAAAATCCAGAAATTCATAGAA TGGCTTAAGGTCAAAATATTACCAGAGGTCAGAGAAAAACATGAATTCCTGAACAGACTC AAGCAGCTCCCTCTGTTGGAAAGCCAGATCGCCACAATCGAGCAAAGTGCGCCGTCCCAG AGTGACCAAGAGCAATTGTTTTCCAATGTCCAGTACTTTGCTCACTATTGCAGGAAGTAT GCTCCCCTCTACGCATCAGAAGCAAAGAGAGTATTCTCCCTTGAGAAGAAGATGAGCAAT TACATACAGTTCAAGTCCAAATGCCGTATTGAACCTGTATGTCTACTTCTACACGGGAGC CCTGGCGCCGGTAAGTCGGTAGCAACAAATCTAATCGGAAGATCACTCGCTGAGAAACTT AACAGCTCAGTGTACACACTACCACCAGACCCAGATCACTTTGACGGATATAAACAGCAG GCCGTGGTGATCGTGGACGACTTGTGCCAGAATCCTGATGGAAAAGATGTCTCTTTGTTC TGCCAAATGGTCTCTAGTGTAGACTTTGTGCCACCTATGGCTGCCTTGGAAGAGAAAGGC ATTCTGTTCACTTCTCTATTCGTCCTGGCGTCAACTAACGCAGGGTCTATCAACGCCCCA ACCGTGTCAGATAGTAGGGCCCTGGCGCGAAGGTTCCACTTCGACATGAACATTGAAGTT ATCTCCATGTACAGCCAAAATGGCAAAATAAATATGCCGATGTCAGAGAAAACGTGTGAT GAAGAGTGTTGTCCAGTCAACTTTAAGAGATGCTGCCCCCTAGTGTGTGGGAAAGCAATT CAGTTTATAGATAGAAGAACTCAAGTCAGATACTCCCTTGACATGCTGGTAACTGAGATG TTCAGGGAATACAATCACAGGCACAGTGTTGGGGCAACCCTTGAAGCGCTATTCCAGGGT CCACCGATATACAGAGAGATTAAGATCAGCGTGGCACCAGAGACACCACCACCACCAGCC ATTGCAGACTTGCTCAAGTCAGTGGACAGTGAAGCCGTGAGAGAGTACTGTAAAGAAAAG GGGTGGCTGGTTCCAGAGGTTAACTCTACCCTACAGATTGAGAAGCACGTTAGTCGGGCC TTCATCTGTTTGCAAGCATTGACCACTTTTGTCTCAGTGGCTGGAATTATTTACATAATC TACAAGCTCTTTGCAGGCTTCCAAGGAGCATACACAGGGATGCCCAATCAGAAACCCAAA GTGCCCACACTCAGGCAGGCAAAAGTGCAAGGACCTGCGTTCGAATTTGCCGTAGCCATG ATGAAGAGGAATTCAAGCACAGTGAAGACCGAATACCGAGAATTCACTATGTTGGGCATT TATGACAGGTGGGCCGTACTGCCACGCCATGCTAAACCTGGACCAACCATTCTGATGAAC AATCAAGAGGTCGGTGTGCTTGACGCCAAGGAACTAGTGGATAAGGATGGCACCAATCTG GAGTTGACACTACTCAAGTTAAACCGGAATGAGAAGTTCAGAGACATCAGAGGCTTCTTG GCCAAAGAGGAGGTGGAAGCTAACCAGGCTGTACTGGCGATTAACACCAGCAAGTTCCCC AACATGTACATCCCAGTGGGTCAAGTCACAGATTACGGTTTCTTAAACTTAGGCGGTACA CCCACCAAGAGAATGCTCATGTCCAACTTCCCCACACGAGCGGGCCAGTGCGGCGGGGTT CTCATGTCCACCGGTAAGGTCTTGGGGATCCACGTTGGTGGAAATGGTCATCAGGGCTTC TCAGCTGCACTCCTCAAGCACTATTTCAATGATGAGCAAGGGGAAATTGAGTTTATTGAG AGTTCAAAGGATGCGGGGTTCCCAATCATTAATACGCCTAGTAAGACTAAGTTGGAACCG AGCGTCTTCCATCAAGTATTCGAAGGGGACAAAGAACCAGCTGTCCTCAGGAACGGTGAT CCACGCCTCAAGGCCAACTTTGAGGAAGCCATATTCTCAAAATACATTGGAAATGTCAAC ACACACGTGGATGAATACATGCTAGAGGCTGTCGATCATTATGCTGGTCAGCTGGCCACA CTGGATATCAGCACCGAACCTATGAGATTGGAGGATGCTGTGTATGGCACCGAGGGCCTC GAAGCCCTTGACCTAACAACGAGTGCAGGCTACCCTTATGTTGCACTAGGCATCAAGAAG AGAGACATCCTTTCAAGGAGGACCAGGGATCTAACCAAGTTGAAGGAATGTATGGATAAA TACGGTTTGAACTTACCGATGGTGACTTATGTGAAAGATGAACTTAGGTCTGCAGACAAA GTAGCAAAAGGGAAGTCTAGGTTGATTGAAGCATCCAGTTTGAATGACTCTGTAGCAATG AGACAAACATTTGGCAACCTGTACAGAACCTTCCATCTAAACCCAGGGATCGTGACTGGT AGCGCTGTCGGGTGCGACCCGGACCTCTTTTGGAGTAAAATTCCAGTGATGTTGGATGGT CACCTCATAGCCTTTGACTACTCTGGATATGATGCTAGCTTGAGCCCCGTGTGGTTTGCC TGCCTAAAACTATTACTTGAGAAATTAGGCTACACACACAAGGAAACAAATTACATTGAC TACCTGTGTAATTCCCACCACCTGTACAGAGACAAACACTACTTTGAGCGGGGTGGTATG CCCTCAGGATATTCCGGCACCAGCATGTTTAACTCAATGATAAACAACATCATCATCAGG ACTCTCATGCTAAAAGTGTATAAGGGAATTGATTTGGACCAGTTTAGGATGATTGCATAC GGTGACGACGTGATTGCGTCATATCCGTGGCCCATCGATGCATCTTTACTTGCCGAAACC GGCAAAGGTTATGGGTTGATTATGACACCAGCAGATAAAGGGGAGTGCTTCAACGAAGTC ACCTGGACCAACGTCACATTCCTGAAGAGGTATTTTAGAGCAGATGAGCAGTATCCCTTC CTGGTACACCCAGTCATGCCCATGAAAGACATCCACGAGTCCATTAGGTGGACCAAAGAC CCAAAGAACACCCAAGACCACGTGCGCTCGCTGTGTTTATTGGCCTGGCATAATGGGGAG CACGAGTATGAGGAGTTCATCCGCAAGATCAGGAGCGTCCCGGTCGGACGTTGCTTGACT CTGCCCGCATTTTCAACCTTGCGTAGGAAGTGGTTGGACTCTTTTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P29813 UniProtKB Entry Name POLG_EC11G GenBank Protein ID 510834 GenBank Gene ID X80059 - General References
- Dahllund L, Nissinen L, Pulli T, Hyttinen VP, Stanway G, Hyypia T: The genome of echovirus 11. Virus Res. 1995 Feb;35(2):215-22. [Article]
- Auvinen P, Hyypia T: Echoviruses include genetically distinct serotypes. J Gen Virol. 1990 Sep;71 ( Pt 9):2133-9. [Article]
- Bergelson JM, Chan M, Solomon KR, St John NF, Lin H, Finberg RW: Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6245-8. [Article]
- Stuart AD, McKee TA, Williams PA, Harley C, Shen S, Stuart DI, Brown TD, Lea SM: Determination of the structure of a decay accelerating factor-binding clinical isolate of echovirus 11 allows mapping of mutants with altered receptor requirements for infection. J Virol. 2002 Aug;76(15):7694-704. [Article]