Heterogeneous nuclear ribonucleoprotein H3

Details

Name
Heterogeneous nuclear ribonucleoprotein H3
Synonyms
  • Heterogeneous nuclear ribonucleoprotein 2H9
  • hnRNP 2H9
  • hnRNP H3
  • HNRPH3
Gene Name
HNRNPH3
Organism
Humans
Amino acid sequence
>lcl|BSEQ0049640|Heterogeneous nuclear ribonucleoprotein H3
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA
FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG
RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG
YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE
FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG
RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY
Number of residues
346
Molecular Weight
36926.445
Theoretical pI
Not Available
GO Classification
Functions
RNA binding
Processes
epithelial cell differentiation / mRNA splicing, via spliceosome / RNA processing / RNA splicing
Components
nucleoplasm / nucleus / spliceosomal complex
General Function
Involved in the splicing process and participates in early heat shock-induced splicing arrest. Due to their great structural variations the different isoforms may possess different functions in the splicing reaction.
Specific Function
Rna binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Nucleus
Gene sequence
>lcl|BSEQ0049641|Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3)
ATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTT
CGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGGTTGGAA
ATCGTGCCAAATGGGATAACATTGACGATGGACTACCAGGGGAGAAGCACAGGGGAGGCC
TTCGTGCAGTTTGCTTCAAAGGAGATAGCAGAAAATGCTCTGGGGAAACACAAGGAAAGA
ATAGGGCACAGGTATATTGAGATCTTCAGAAGTAGCAGGAGTGAAATCAAAGGATTTTAT
GATCCACCAAGAAGATTGCTGGGACAGCGACCGGGACCATATGATAGACCAATAGGAGGA
AGAGGGGGTTATTATGGAGCTGGGCGTGGAAGTATGTATGACAGAATGCGACGAGGAGGT
GATGGATATGATGGTGGTTATGGAGGTTTTGATGACTATGGTGGCTATAATAATTACGGC
TATGGGAATGATGGCTTTGATGACAGAATGAGAGATGGAAGAGGTATGGGAGGACATGGC
TATGGTGGAGCTGGTGATGCAAGTTCAGGTTTTCATGGTGGTCATTTCGTACATATGAGA
GGGTTGCCTTTTCGTGCAACTGAAAATGACATTGCTAATTTCTTCTCACCACTAAATCCA
ATACGAGTTCATATTGATATTGGAGCTGATGGCAGAGCCACAGGAGAAGCAGATGTAGAG
TTTGTGACACATGAAGATGCAGTAGCTGCCATGTCTAAAGATAAAAATAACATGCAACAT
CGATATATTGAACTCTTCTTGAATTCTACTCCTGGAGGCGGCTCTGGCATGGGAGGTTCT
GGAATGGGAGGCTACGGAAGAGATGGAATGGATAATCAGGGAGGCTATGGATCAGTTGGA
AGAATGGGAATGGGGAACAATTACAGTGGAGGATATGGTACTCCTGATGGTTTGGGTGGT
TATGGCCGTGGTGGTGGAGGCAGTGGAGGTTACTATGGGCAAGGCGGCATGAGTGGAGGT
GGATGGCGTGGGATGTACTGA
Chromosome Location
10
Locus
10q21.3
External Identifiers
ResourceLink
UniProtKB IDP31942
UniProtKB Entry NameHNRH3_HUMAN
HGNC IDHGNC:5043
General References
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  2. Honore B: The hnRNP 2H9 gene, which is involved in the splicing reaction, is a multiply spliced gene. Biochim Biophys Acta. 2000 Jun 21;1492(1):108-19. [Article]
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB09130Copperapproved, investigationalunknownDetails