Pur operon repressor
Details
- Name
- Pur operon repressor
- Synonyms
- yabI
- Gene Name
- purR
- Organism
- Bacillus subtilis (strain 168)
- Amino acid sequence
>lcl|BSEQ0019158|Pur operon repressor MKFRRSGRLVDLTNYLLTHPHELIPLTFFSERYESAKSSISEDLTIIKQTFEQQGIGTLL TVPGAAGGVKYIPKMKQAEAEEFVQTLGQSLANPERILPGGYVYLTDILGKPSVLSKVGK LFASVFAEREIDVVMTVATKGIPLAYAAASYLNVPVVIVRKDNKVTEGSTVSINYVSGSS NRIQTMSLAKRSMKTGSNVLIIDDFMKAGGTINGMINLLDEFNANVAGIGVLVEAEGVDE RLVDEYMSLLTLSTINMKEKSIEIQNGNFLRFFKDNLLKNGETES
- Number of residues
- 285
- Molecular Weight
- 31228.72
- Theoretical pI
- 5.92
- GO Classification
- FunctionsDNA bindingProcessesnegative regulation of purine nucleobase metabolic process / negative regulation of transcription, DNA-templated / nucleoside metabolic process / transcription, DNA-templated
- General Function
- Dna binding
- Specific Function
- Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0019159|Pur operon repressor (purR) ATGAAGTTTCGTCGCAGCGGCAGATTGGTGGACTTAACAAATTATTTGTTAACCCATCCG CACGAGTTAATACCGCTAACCTTTTTCTCTGAGCGGTATGAATCTGCAAAATCATCGATC AGTGAAGATTTAACAATTATTAAACAAACCTTTGAACAGCAGGGGATTGGTACTTTGCTT ACTGTTCCCGGAGCTGCCGGAGGCGTTAAATATATTCCGAAAATGAAGCAGGCTGAAGCT GAAGAGTTTGTGCAGACACTTGGACAGTCGCTGGCAAATCCTGAGCGTATCCTTCCGGGC GGTTATGTATATTTAACGGATATCTTAGGAAAGCCATCTGTACTCTCCAAGGTAGGGAAG CTGTTTGCTTCCGTGTTTGCAGAGCGCGAAATTGATGTTGTCATGACCGTTGCCACGAAA GGCATCCCTCTTGCGTACGCAGCTGCAAGCTATTTGAATGTGCCTGTTGTGATCGTTCGT AAAGACAATAAGGTAACAGAGGGCTCCACAGTCAGCATTAATTACGTTTCAGGCTCCTCA AACCGCATTCAAACAATGTCACTTGCGAAAAGAAGCATGAAAACGGGTTCAAACGTACTC ATTATTGATGACTTTATGAAAGCAGGCGGCACCATTAATGGTATGATTAACCTGTTGGAT GAGTTTAACGCAAATGTGGCGGGAATCGGCGTCTTAGTTGAAGCCGAAGGAGTAGATGAA CGTCTTGTTGACGAATATATGTCACTTCTTACTCTTTCAACCATCAACATGAAAGAGAAG TCCATTGAAATTCAGAATGGCAATTTTCTGCGTTTTTTTAAAGACAATCTTTTAAAGAAT GGAGAGACAGAATCATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P37551 UniProtKB Entry Name PURR_BACSU GenBank Protein ID 467436 GenBank Gene ID D26185 - General References
- Ogasawara N, Nakai S, Yoshikawa H: Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin. DNA Res. 1994;1(1):1-14. [Article]
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- Weng M, Nagy PL, Zalkin H: Identification of the Bacillus subtilis pur operon repressor. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7455-9. [Article]