Catalase
Details
- Name
- Catalase
- Synonyms
- 1.11.1.6
- Gene Name
- katA
- Organism
- Proteus mirabilis
- Amino acid sequence
>lcl|BSEQ0016639|Catalase MEKKKLTTAAGAPVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGA FGTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEG NWDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYKWDFFSHLPESLHQLTIDMS DRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHFRCQQGIKNLMDDEAEALVGKDRESS QRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELNRN PDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPKCP FHNYHRDGAMRVDGNSGNGITYEPNSGGVFQEQPDFKEPPLSIEGAADHWNHREDEDYFS QPRALYELLSDDEHQRMFARIAGELSQASKETQQRQIDLFTKVHPEYGAGVEKAIKVLEG KDAK
- Number of residues
- 484
- Molecular Weight
- 55614.085
- Theoretical pI
- 6.56
- GO Classification
- Functionscatalase activity / heme binding / metal ion bindingProcesseshydrogen peroxide catabolic process / response to oxidative stressComponentscytoplasm
- General Function
- Metal ion binding
- Specific Function
- Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P42321 UniProtKB Entry Name CATA_PROMI - General References
- Buzy A, Bracchi V, Sterjiades R, Chroboczek J, Thibault P, Gagnon J, Jouve HM, Hudry-Clergeon G: Complete amino acid sequence of Proteus mirabilis PR catalase. Occurrence of a methionine sulfone in the close proximity of the active site. J Protein Chem. 1995 Feb;14(2):59-72. [Article]
- Gouet P, Jouve HM, Dideberg O: Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH. J Mol Biol. 1995 Jun 23;249(5):933-54. [Article]
- Gouet P, Jouve HM, Williams PA, Andersson I, Andreoletti P, Nussaume L, Hajdu J: Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy. Nat Struct Biol. 1996 Nov;3(11):951-6. [Article]
- Andreoletti P, Sainz G, Jaquinod M, Gagnon J, Jouve HM: High-resolution structure and biochemical properties of a recombinant Proteus mirabilis catalase depleted in iron. Proteins. 2003 Feb 1;50(2):261-71. [Article]