Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Details
- Name
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
- Synonyms
- G gamma-I
- Gene Name
- GNG2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0016306|Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP FREKKFFCAIL
- Number of residues
- 71
- Molecular Weight
- 7850.03
- Theoretical pI
- 8.22
- GO Classification
- FunctionsG-protein beta-subunit binding / signal transducer activityProcessesadenylate cyclase-activating dopamine receptor signaling pathway / blood coagulation / cell proliferation / cellular response to catecholamine stimulus / cellular response to glucagon stimulus / cellular response to prostaglandin E stimulus / energy reserve metabolic process / platelet activation / small molecule metabolic process / synaptic transmissionComponentsextracellular exosome / heterotrimeric G-protein complex / membrane / plasma membrane
- General Function
- Signal transducer activity
- Specific Function
- Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
- Pfam Domain Function
- G-gamma (PF00631)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0016307|Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (GNG2) ATGGCCAGCAACAACACCGCCAGCATAGCACAAGCCAGGAAGCTGGTAGAGCAGCTTAAG ATGGAAGCCAATATCGACAGGATAAAGGTGTCCAAGGCAGCTGCAGATTTGATGGCCTAC TGTGAAGCACATGCCAAGGAAGACCCCCTCCTGACCCCTGTTCCGGCTTCAGAAAACCCG TTTAGGGAGAAGAAGTTTTTCTGTGCCATCCTTTAA
- Chromosome Location
- 14
- Locus
- 14q21
- External Identifiers
Resource Link UniProtKB ID P59768 UniProtKB Entry Name GBG2_HUMAN GenBank Protein ID 20147633 GenBank Gene ID AF493870 GenAtlas ID GNG2 HGNC ID HGNC:4404 - General References
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