Catalase
Details
- Name
- Catalase
- Synonyms
- 1.11.1.6
- Gene Name
- katA
- Organism
- Helicobacter pylori (strain ATCC 700392 / 26695)
- Amino acid sequence
>lcl|BSEQ0011880|Catalase MVNKDVKQTTAFGAPVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGS GAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTE EGNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPNHDMVWDFWSNVPESLYQVTWV MSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEVRKYDPD SNQRDLFNAIARGDFPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYLQDYPLMEVGIVELN KNPENYFAEVEQAAFSPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNKPR CPFHSSSRDGYMQNGYYGSLQNYTPSSLPGYKEDKSARDPKFNLAHIEKEFEVWNWDYRA DDSDYYTQPGDYYRSLPADEKERLHDTIGESLAHVTHKEIVDKQLEHFKKADPKYAEGVK KALEKHQKMMKDMHGKDMHHTKKKK
- Number of residues
- 505
- Molecular Weight
- 58628.85
- Theoretical pI
- 9.04
- GO Classification
- Functionscatalase activity / heme binding / metal ion bindingProcesseshydrogen peroxide catabolic process / response to oxidative stressComponentscytoplasm
- General Function
- Metal ion binding
- Specific Function
- Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011881|Catalase (katA) ATGGTTAATAAAGATGTGAAACAAACCACTGCTTTTGGCGCTCCCGTTTGGGATGACAAC AATGTGATTACGGCCGGCCCTAGAGGTCCTGTTTTATTACAAAGCACTTGGTTTTTGGAA AAGTTAGCGGCGTTTGACAGAGAAAGAATCCCTGAAAGGGTGGTGCATGCTAAAGGAAGC GGAGCTTATGGCACTTTCACTGTGACTAAAGACATCACTAAATACACTAAAGCGAAAATT TTCTCTAAAGTGGGCAAAAAAACCGAATGCTTCTTCAGATTTTCTACTGTGGCTGGTGAA AGAGGCAGTGCGGATGCGGTGAGAGACCCTAGAGGTTTTGCGATGAAGTATTACACTGAA GAAGGTAACTGGGATTTAGTGGGGAACAACACGCCTGTTTTCTTTATCCGTGATGCGATC AAATTCCCTGATTTCATCCACACTCAAAAACGAGATCCTCAAACCAATTTGCCTAACCAT GACATGGTATGGGATTTTTGGAGTAATGTTCCTGAAAGCTTATACCAAGTAACATGGGTT ATGAGCGATAGGGGTATTCCTAAATCTTTCCGCCACATGGATGGTTTTGGCAGCCACACT TTCAGTCTTATCAACGCGAAAGGCGAACGCTTTTGGGTGAAATTCCACTTTCACACCATG CAAGGCGTTAAGCATTTGACTAACGAAGAAGCCGCAGAAGTTAGGAAGTATGATCCGGAT TCCAATCAAAGGGATTTATTCAATGCGATCGCTAGAGGGGATTTCCCAAAATGGAAATTA AGCATTCAAGTGATGCCAGAAGAAGATGCTAAGAAGTATCGATTCCATCCGTTTGATGTA ACTAAAATTTGGTATCTCCAAGATTATCCATTGATGGAAGTGGGCATTGTGGAGTTGAAT AAAAATCCTGAAAACTATTTCGCAGAAGTGGAACAAGCGGCATTCAGTCCGGCTAATGTC GTTCCTGGAATTGGCTATAGCCCTGATAGGATGTTACAAGGGCGCTTGTTCTCTTATGGA GACACACACCGCTACCGCTTAGGCGTTAATTATCCTCAAATACCGGTTAATAAACCAAGA TGCCCATTCCACTCTTCTAGCAGAGATGGTTACATGCAAAACGGATACTACGGCTCTTTA CAAAACTATACGCCTAGCTCATTGCCTGGCTATAAAGAAGATAAGAGCGCGAGAGATCCT AAGTTCAACTTAGCTCATATTGAGAAAGAGTTTGAAGTGTGGAATTGGGATTACAGAGCT GATGATAGCGATTACTACACCCAACCAGGTGATTACTACCGCTCATTGCCAGCTGATGAA AAAGAAAGGTTGCATGACACTATTGGAGAGTCTTTAGCTCATGTTACCCATAAGGAAATT GTGGATAAACAATTGGAGCATTTCAAGAAAGCTGACCCCAAATACGCTGAGGGAGTTAAA AAAGCTCTTGAAAAACACCAAAAAATGATGAAAGACATGCATGGAAAAGACATGCACCAC ACAAAAAAGAAAAAGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P77872 UniProtKB Entry Name CATA_HELPY GenBank Gene ID U67458 - General References
- Manos J, Kolesnikow T, Hazell SL: An investigation of the molecular basis of the spontaneous occurrence of a catalase-negative phenotype in Helicobacter pylori. Helicobacter. 1998 Mar;3(1):28-38. [Article]
- Odenbreit S, Wieland B, Haas R: Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain. J Bacteriol. 1996 Dec;178(23):6960-7. [Article]
- Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC: The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature. 1997 Aug 7;388(6642):539-47. [Article]