Cathepsin L2

Details

Name
Cathepsin L2
Synonyms
  • 3.4.22.15
Gene Name
Not Available
Organism
Fasciola hepatica
Amino acid sequence
>lcl|BSEQ0052093|Cathepsin L2
AVPDKIDRRESGYV
Number of residues
14
Molecular Weight
1604.765
Theoretical pI
Not Available
GO Classification
Functions
cysteine-type peptidase activity
Components
lysosome
General Function
Thiol protease that assists the parasite in burrowing through the gut wall and liver of its mammalian host.
Specific Function
Cysteine-type peptidase activity
Pfam Domain Function
Not Available
Transmembrane Regions
Not Available
Cellular Location
Lysosome
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP80342
UniProtKB Entry NameCATL2_FASHE
General References
  1. Dowd AJ, Smith AM, McGonigle S, Dalton JP: Purification and characterisation of a second cathepsin L proteinase secreted by the parasitic trematode Fasciola hepatica. Eur J Biochem. 1994 Jul 1;223(1):91-8. doi: 10.1111/j.1432-1033.1994.tb18969.x. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB12245Triclabendazoleapproved, investigationalunknowninhibitorDetails