Chondroitinase (Chondroitin lyase)

Details

Name

Chondroitinase (Chondroitin lyase)

Synonyms

• Chondroitin lyase

Gene Name

Not Available

Organism

Arthrobacter aurescens

Amino acid sequence

>lcl|BSEQ0022422|Chondroitinase (Chondroitin lyase)
EAEPGAAEFAALRNRWVDQITGRNVIQAGDPDFAKAITALNNKAADSLAKLDVKKGRTSV
FTDLSLAKDAEMVTTYTRLSQLATAWATPTAAVFGDAAVLAAIKAGLADANTLCYNDRKE
EVGNWWSWEIGVPRALADAMVLLHAELSAAERTAYCAAIDHFVPDPWLQFPPKRGKITSV
GANRVDLCQGIIIRSLAGEDPTKLNHAVAGLSQVWQYVTSGDGIFRDGSFIQHSTTPYTG
SYGVVLLTGLSKLFSLLGGTAFEVSDPTRSIFFDAVEGSFAPVMINGAMADAVRGRSISR
EANTGYDLGASAIEAILLLARAMDPATAARWRGLCAGWIARDTYRPILNSASVPRTALVK
QLEATGVAPVAEATGHKLFPAMDRTMHRGPGWALSLALSSNRIAWYECGNGENNRGYHTG
SGMTYFYTSDLGQYDDAFWATANYNRLPGITVDTTPLPDKVEGQWGAAVPADEWSGATAL
GEVAAVGQHLVGPGRTGLTARKSWFVSGDVTVCLGADISTASGAKVETIVDHRNLHQGSN
TLTTAAGTIAGTAGTVEVLGDGRWVHLEGFGGYAMLDDSPLHVLRETRSGSWSGVNINGS
ATVQQRNFATLYVNHGVGPVAGSYAYMVAPGASVDLTRKLLEGNKYSVIRNDATAQSVEF
KTAKTTAATFWKPGMAGDLGASGPACVVFSRHGNELSLAVSEPTQKAAGLTLTLPEGTWS
SVLEGAGTLGTDADGRSTLTLDTTGLSGKTKLIKLKR

Number of residues

757

Molecular Weight

79927.28

Theoretical pI

6.52

GO Classification

Functions

carbohydrate binding / carbon-oxygen lyase activity, acting on polysaccharides

Processes

carbohydrate metabolic process

Components

extracellular region

General Function

Carbon-oxygen lyase activity, acting on polysaccharides

Specific Function

Not Available

Pfam Domain Function

• Lyase_8 (PF02278)
• Lyase_8_C (PF02884)
• Lyase_8_N (PF08124)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	P84141
UniProtKB Entry Name	P84141_ARTAU

General References

1. Lunin VV, Li Y, Linhardt RJ, Miyazono H, Kyogashima M, Kaneko T, Bell AW, Cygler M: High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism. J Mol Biol. 2004 Mar 19;337(2):367-86. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB01872	2-deoxy-2-acetamido-beta-D-galactose-4-sulfate	experimental	unknown		Details
DB02227	4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid	experimental	unknown		Details
DB03284	2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid	experimental	unknown		Details