Actin-1
Details
- Name
- Actin-1
- Synonyms
- Actin I
- PfACT1
- Gene Name
- Not Available
- Organism
- Plasmodium falciparum (isolate HB3)
- Amino acid sequence
>lcl|BSEQ0051360|Actin-1 MGEEDVQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPKNPGIMVGMEEKDAFVGDEAQ TKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNRERM TQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLD LAGRDLTEYLMKILHERGYGFSTSAEKEIVRDIKEKLCYIALNFDEEMKTSEQSSDIEKS YELPDGNIITVGNERFRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVL SGGTTMYEGIGERLTRDITTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWITK EEYDESGPSIVHRKCF
- Number of residues
- 376
- Molecular Weight
- 41870.305
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / structural constituent of cytoskeletonProcessesactin polymerization-dependent cell motility involved in migration of symbiont in hostComponentsactin filament / cytoplasm
- General Function
- Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Actin assembles into short polymer microfilaments, these are thought to contribute to parasite gliding motility.
- Specific Function
- Atp binding
- Pfam Domain Function
- Actin (PF00022)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P86287 UniProtKB Entry Name ACT1_PLAFX - General References
- Schuler H, Mueller AK, Matuschewski K: Unusual properties of Plasmodium falciparum actin: new insights into microfilament dynamics of apicomplexan parasites. FEBS Lett. 2005 Jan 31;579(3):655-60. doi: 10.1016/j.febslet.2004.12.037. [Article]