Hexokinase

Details

Name

Hexokinase

Synonyms

• 2.7.1.1

Gene Name

Not Available

Organism

Blood fluke

Amino acid sequence

>lcl|BSEQ0019399|Hexokinase
MVFSDQQLFEKVVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTK
TPNGTETGNFLALDLGGTNYRVLSVTLEGKGKSPRIQERTYCIPAEKMSGSGTELFKYIA
ETLADFLENNGMKDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQT
ELDKRELNVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGVK
EPEVVINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIV
YLVEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEPIDN
RIVRYACEMVVKRAAYLAGAGIACILRRINRSEVTVGVDGSLYKFHPKFCERMTDMVDKL
KPKNTRFCLRLSEDGSGKGAAAIAASCTRQN

Number of residues

451

Molecular Weight

50445.62

Theoretical pI

6.14

GO Classification

Functions

ATP binding / glucose binding / hexokinase activity

Processes

cellular glucose homeostasis / glycolytic process

Components

cell

General Function

Hexokinase activity

Specific Function

Not Available

Pfam Domain Function

• Hexokinase_1 (PF00349)
• Hexokinase_2 (PF03727)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0006328|1356 bp
ATGGTGTTTTCAGACCAGCAACTTTTTGAGAAAGTAGTCGAGATACTCAAGCCATTTGAT
CTTTCTGTGGTTGATTATGAGGAGATTTGTGATAGGATGGGAGAATCAATGCGACTAGGT
TTACAGAAGAGTACAAATGAAAAATCATCTATTAAAATGTTTCCATCTTATGTTACAAAA
ACACCAAATGGGACAGAAACCGGAAACTTCTTAGCTTTAGACCTTGGTGGAACAAATTAT
CGAGTGCTTTCAGTTACCCTTGAAGGTAAAGGAAAATCTCCAAGAATTCAAGAGAGAACA
TACTGTATCCCCGCAGAAAAAATGTCAGGTTCCGGAACAGAGCTCTTTAAATATATTGCT
GAGACACTGGCTGACTTTTTGGAAAACAACGGGATGAAGGACAAAAAGTTTGACCTCGGA
TTCACATTCTCTTTTCCATGTGTCCAAAAAGGCCTCACTCATGCTACTTTGGTGAGATGG
ACAAAAGGTTTCTCTGCAGATGGAGTAGAAGGTCATAATGTTGCTGAATTGCTGCAAACT
GAGCTAGACAAAAGAGAATTAAATGTTAAGTGTGTCGCGGTTGTAAACGATACAGTTGGC
ACACTTGCTTCTTGTGCTCTTGAGGACCCAAAATGTGCGGTCGGATTAATAGTTGGGACG
GGGACAAACGTTGCTTATATTGAGGACTCTTCGAAAGTTGAGCTGATGGATGGTGTGAAG
GAACCCGAAGTCGTCATAAACACAGAGTGGGGTGCATTCGGCGAGAAAGGAGAATTAGAC
TGTTGGAGGACACAGTTCGACAAATCAATGGATATAGACAGTCTTCATCCAGGAAAGCAA
CTATATGAAAAAATGGTATCTGGGATGTATCTTGGTGAGCTAGTTCGCCACATCATTGTT
TACCTTGTTGAACAAAAAATTCTCTTTCGTGGAGATCTCCCTGAACGTTTGAAAGTACGC
AATTCTTTGCTAACTAGATACTTAACGGATGTTGAAAGAGATCCTGCTCACCTTTTATAC
AACACTCATTATATGCTTACTGATGACTTGCATGTCCCTGTTGTTGAGCCGATAGATAAC
CGTATAGTACGATATGCCTGTGAAATGGTCGTTAAACGGGCAGCTTACCTAGCAGGTGCA
GGTATTGCCTGCATTCTTCGAAGAATAAACCGCTCAGAAGTAACTGTTGGTGTTGATGGC
TCTTTGTATAAATTCCACCCGAAGTTTTGTGAACGAATGACAGATATGGTTGATAAGCTA
AAACCAAAGAATACACGATTCTGTCTACGTTTATCTGAAGATGGAAGTGGAAAAGGAGCG
GCGGCCATAGCAGCGTCATGTACACGACAAAATTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q26609
UniProtKB Entry Name	HXK_SCHMA
GenBank Gene ID	L04480

General References

1. Shoemaker CB, Reynolds SR, Wei G, Tielens AG, Harn DA: Schistosoma mansoni hexokinase: cDNA cloning and immunogenicity studies. Exp Parasitol. 1995 Feb;80(1):36-45. [Article]
2. Mulichak AM, Wilson JE, Padmanabhan K, Garavito RM: The structure of mammalian hexokinase-1. Nat Struct Biol. 1998 Jul;5(7):555-60. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB02379	Beta-D-Glucose	experimental	unknown		Details