Adhesin
Details
- Name
- Adhesin
- Synonyms
- Hia
- Gene Name
- hia
- Organism
- Haemophilus influenzae
- Amino acid sequence
>lcl|BSEQ0022339|Adhesin MNKIFNVIWNVVTQTWVVVSELTRTHTKCASATVAVAVLATLLSATVEANNNTPVTNKLK AYGDANFNFTNNSIADAEKQVQEAYKGLLNLNEKNASDKLLVEDNTAATVGNLRKLGWVL SSKNGTRNEKSQQVKHADEVLFEGKGGVQVTSTSENGKHTITFALAKDLGVKTATVSDTL TIGGGAAAGATTTPKVNVTSTTDGLKFAKDAAGANGDTTVHLNGIGSTLTDTLVGSPATH IDGGDQSTHYTRAASIKDVLNAGWNIKGVKAGSTTGQSENVDFVHTYDTVEFLSADTETT TVTVDSKENGKRTEVKIGAKTSVIKEKDGKLFTGKANKETNKVDGANATEDADEGKGLVT AKDVIDAVNKTGWRIKTTDANGQNGDFATVASGTNVTFASGNGTTATVTNGTDGITVKYD AKVGDGLKLDGDKIAADTTALTVNDGKNANNPKGKVADVASTDEKKLVTAKGLVTALNSL SWTTTAAEADGGTLDGNASEQEVKAGDKVTFKAGKNLKVKQEGANFTYSLQDALTGLTSI TLGTGNNGAKTEINKDGLTITPANGAGANNANTISVTKDGISAGGQSVKNVVSGLKKFGD ANFDPLTSSADNLTKQNDDAYKGLTNLDEKGTDKQTPVVADNTAATVGDLRGLGWVISAD KTTGGSTEYHDQVRNANEVKFKSGNGINVSGKTVNGRREITFELAKGEVVKSNEFTVKET NGKETSLVKVGDKYYSKEDIDLTTGQPKLKDGNTVAAKYQDKGGKVVSVTDNTEATITNK GSGYVTGNQVADAIAKSGFELGLADEADAKAAFDDKTKALSAGTTEIVNAHDKVRFANGL NTKVSAATVESTDANGDKVTTTFVKTDVELPLTQIYNTDANGKKITKVVKDGQTKWYELN ADGTADMTKEVTLGNVDSDGKKVVKDNDGKWYHAKADGTADKTKGEVSNDKVSTDEKHVV SLDPNDQSKGKGVVIDNVANGDISATSTDAINGSQLYAVAKGVTNLAGQVNNLEGKVNKV GKRADAGTASALAASQLPQATMPGKSMVAIAGSSYQGQNGLAIGVSRISDNGKVIIRLSG TTNSQGKTGVAAGVGYQW
- Number of residues
- 1098
- Molecular Weight
- 114014.485
- Theoretical pI
- 6.35
- GO Classification
- ProcessespathogenesisComponentsouter membrane
- General Function
- Not Available
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0007598|3297 bp ATGAACAAAATTTTTAACGTTATTTGGAATGTTGTGACTCAAACTTGGGTTGTCGTATCT GAACTCACTCGCACCCACACCAAATGCGCCTCCGCCACCGTGGCGGTTGCCGTATTGGCA ACCCTGTTGTCCGCAACGGTTGAGGCGAACAACAATACTCCTGTTACGAATAAGTTGAAG GCTTATGGCGATGCGAATTTTAATTTCACTAATAATTCGATAGCAGATGCAGAAAAACAA GTTCAAGAGGCTTATAAAGGTTTATTAAATCTAAATGAAAAAAATGCGAGTGATAAACTG TTGGTGGAGGACAATACTGCGGCGACCGTAGGCAATTTGCGTAAATTGGGCTGGGTATTG TCTAGCAAAAACGGCACAAGGAACGAGAAAAGCCAACAAGTCAAACATGCGGATGAAGTG TTGTTTGAAGGCAAAGGCGGTGTGCAGGTTACTTCCACCTCTGAAAACGGCAAACACACC ATTACCTTTGCTTTAGCGAAAGACCTTGGTGTGAAAACTGCGACTGTGAGTGATACCTTA ACGATTGGCGGTGGTGCTGCTGCAGGTGCTACAACAACACCGAAAGTGAATGTAACTAGT ACAACTGATGGCTTGAAGTTCGCTAAAGATGCTGCGGGTGCTAATGGCGATACTACGGTT CACTTGAATGGTATTGGTTCAACCTTGACAGACACGCTTGTGGGTTCTCCTGCTACTCAT ATTGACGGAGGAGATCAAAGTACGCATTACACTCGTGCAGCAAGTATCAAGGATGTCTTG AATGCGGGTTGGAATATCAAGGGTGTTAAAGCTGGCTCAACAACTGGTCAATCAGAAAAT GTCGATTTTGTTCATACTTACGATACTGTTGAGTTCTTGAGTGCGGATACAGAGACCACG ACTGTTACTGTAGATAGCAAAGAAAACGGTAAGAGAACCGAAGTTAAAATCGGTGCGAAG ACTTCTGTTATCAAAGAAAAAGACGGTAAGTTATTTACTGGAAAAGCTAACAAAGAGACA AATAAAGTTGATGGTGCTAACGCGACTGAAGATGCAGACGAAGGCAAAGGCTTAGTGACT GCGAAAGATGTGATTGACGCAGTGAATAAGACTGGTTGGAGAATTAAAACAACCGATGCT AATGGTCAAAATGGCGACTTCGCAACTGTTGCATCAGGCACAAATGTAACCTTTGCTAGT GGTAATGGTACAACTGCGACTGTAACTAATGGCACCGATGGTATTACCGTTAAGTATGAT GCGAAAGTTGGCGACGGCTTAAAACTAGATGGCGATAAAATCGCTGCAGATACGACCGCA CTTACTGTGAATGATGGTAAGAACGCTAATAATCCGAAAGGTAAAGTGGCTGATGTTGCT TCAACTGACGAGAAGAAATTGGTTACAGCAAAAGGTTTAGTAACAGCCTTAAACAGTCTA AGCTGGACTACAACTGCTGCTGAGGCGGACGGTGGTACGCTTGATGGAAATGCAAGTGAG CAAGAAGTTAAAGCGGGCGATAAAGTAACCTTTAAAGCAGGCAAGAACTTAAAAGTGAAA CAAGAGGGTGCGAACTTTACTTATTCACTGCAAGATGCTTTAACAGGCTTAACGAGCATT ACTTTAGGTACAGGAAATAATGGTGCGAAAACTGAAATCAACAAAGACGGCTTAACCATC ACACCAGCAAATGGTGCGGGTGCAAATAATGCAAACACCATCAGCGTAACCAAAGACGGC ATTAGTGCGGGCGGTCAGTCGGTTAAAAACGTTGTGAGCGGACTGAAGAAATTTGGTGAT GCGAATTTCGATCCGCTGACTAGCTCCGCCGACAACTTAACGAAACAAAATGACGATGCC TATAAAGGCTTGACCAATTTGGATGAAAAAGGTACAGACAAGCAAACTCCAGTTGTTGCC GACAATACCGCCGCAACCGTGGGCGATTTGCGCGGCTTGGGCTGGGTCATTTCTGCGGAC AAAACCACAGGCGGCTCAACGGAATATCACGATCAAGTTCGGAATGCGAACGAAGTGAAA TTCAAAAGCGGCAACGGTATCAATGTTTCCGGTAAAACGGTCAACGGTAGGCGTGAAATT ACTTTTGAATTGGCTAAAGGTGAAGTGGTTAAATCGAATGAATTTACCGTCAAAGAAACC AATGGAAAGGAAACGAGCCTGGTTAAAGTTGGCGATAAATATTACAGCAAAGAGGATATT GACTTAACAACTGGTCAGCCTAAATTAAAAGATGGCAATACAGTTGCTGCGAAATATCAA GATAAAGGTGGCAAAGTCGTTTCTGTAACGGATAATACTGAAGCTACCATAACCAACAAA GGTTCTGGCTATGTAACAGGTAACCAAGTGGCAGATGCGATTGCGAAATCAGGCTTTGAG CTTGGCTTGGCTGATGAAGCTGATGCGAAAGCGGCGTTTGATGATAAGACAAAAGCCTTA TCTGCTGGTACAACGGAAATTGTAAATGCCCACGATAAAGTCCGTTTTGCTAATGGTTTA AATACCAAAGTGAGCGCGGCAACGGTGGAAAGCACCGATGCAAACGGCGATAAAGTGACC ACAACCTTTGTGAAAACCGATGTGGAATTGCCTTTAACGCAAATCTACAATACCGATGCA AACGGTAAGAAAATCACTAAAGTTGTCAAAGATGGGCAAACTAAATGGTATGAACTGAAT GCTGACGGTACGGCTGATATGACCAAAGAAGTTACCCTCGGTAACGTGGATTCAGACGGC AAGAAAGTTGTGAAAGACAACGATGGCAAGTGGTATCACGCCAAAGCTGACGGTACTGCG GATAAAACCAAAGGCGAAGTGAGCAATGATAAAGTTTCTACCGATGAAAAACACGTTGTC AGCCTTGATCCAAATGATCAATCAAAAGGTAAAGGTGTCGTGATTGACAATGTGGCTAAT GGCGATATTTCTGCCACTTCCACCGATGCGATTAACGGAAGTCAGTTGTATGCTGTGGCA AAAGGGGTAACAAACCTTGCTGGACAAGTGAATAATCTTGAGGGCAAAGTGAATAAAGTG GGCAAACGTGCAGATGCAGGTACAGCAAGTGCATTAGCGGCTTCACAGTTACCACAAGCC ACTATGCCAGGTAAATCAATGGTTGCTATTGCGGGAAGTAGTTATCAAGGTCAAAATGGT TTAGCTATCGGGGTATCAAGAATTTCCGATAATGGCAAAGTGATTATTCGCTTGTCAGGC ACAACCAATAGTCAAGGTAAAACAGGCGTTGCAGCAGGTGTTGGTTACCAGTGGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q48152 UniProtKB Entry Name Q48152_HAEIF GenBank Protein ID 21536216 GenBank Gene ID U38617 - General References
- Barenkamp SJ, St Geme JW 3rd: Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typable Haemophilus influenzae. Mol Microbiol. 1996 Mar;19(6):1215-23. [Article]
- Laarmann S, Cutter D, Juehne T, Barenkamp SJ, St Geme JW: The Haemophilus influenzae Hia autotransporter harbours two adhesive pockets that reside in the passenger domain and recognize the same host cell receptor. Mol Microbiol. 2002 Nov;46(3):731-43. [Article]
- Yeo HJ, Cotter SE, Laarmann S, Juehne T, St Geme JW 3rd, Waksman G: Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter. EMBO J. 2004 Mar 24;23(6):1245-56. Epub 2004 Mar 18. [Article]
- Meng G, Surana NK, St Geme JW 3rd, Waksman G: Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter. EMBO J. 2006 Jun 7;25(11):2297-304. Epub 2006 May 11. [Article]
- Meng G, St Geme JW 3rd, Waksman G: Repetitive architecture of the Haemophilus influenzae Hia trimeric autotransporter. J Mol Biol. 2008 Dec 26;384(4):824-36. doi: 10.1016/j.jmb.2008.09.085. Epub 2008 Oct 11. [Article]