Cholera enterotoxin B subunit

Details

Name
Cholera enterotoxin B subunit
Synonyms
  • Cholera enterotoxin subunit B
  • Cholera toxin B protein (CTB)
  • Cholera toxin B subunit
  • Cholera toxin beta subunit
  • Cholera toxin subunit B
  • Cholerae toxin B subunit
  • CtxB
Gene Name
ctxB
Organism
Vibrio cholerae
Amino acid sequence
>lcl|BSEQ0019531|Cholera enterotoxin B subunit
MIKLKFGVFFTVLLSSAYAHGTPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAI
ITFKNGATFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAI
SMAN
Number of residues
124
Molecular Weight
13918.975
Theoretical pI
9.13
GO Classification
Processes
pathogenesis
Components
extracellular region
General Function
Not Available
Specific Function
Not Available
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ57193
UniProtKB Entry NameQ57193_VIBCL
GenBank Protein ID847822
GenBank Gene IDU25679
General References
  1. Fan E, Merritt EA, Zhang Z, Pickens JC, Roach C, Ahn M, Hol WG: Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):201-12. [Article]
  2. Merritt EA, Zhang Z, Pickens JC, Ahn M, Hol WG, Fan E: Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin. J Am Chem Soc. 2002 Jul 31;124(30):8818-24. [Article]
  3. Mitchell DD, Pickens JC, Korotkov K, Fan E, Hol WG: 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies. Bioorg Med Chem. 2004 Mar 1;12(5):907-20. [Article]
  4. Okada K, Natakuathung W, Na-Ubol M, Roobthaisong A, Wongboot W, Maruyama F, Nakagawa I, Chantaroj S, Hamada S: Characterization of 3 Megabase-Sized Circular Replicons from Vibrio cholerae. Emerg Infect Dis. 2015 Jul;21(7):1262-3. doi: 10.3201/eid2107.141055. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB030773-Amino-4-{3-[2-(2-Propoxy-Ethoxy)-Ethoxy]-Propylamino}-Cyclobut-3-Ene-1,2-DioneexperimentalunknownDetails