TetR family transcriptional regulator
Details
- Name
- TetR family transcriptional regulator
- Synonyms
- TetR family transcriptional repressor LfrR
- Gene Name
- lfrR
- Organism
- Mycobacterium smegmatis
- Amino acid sequence
>lcl|BSEQ0013012|TetR family transcriptional regulator MTSPSIESGARERTRRAILDAAMLVLADHPTAALGDIAAAAGVGRSTVHRYYPERTDLLR ALARHVHDLSNAAIERADPTSGPVDAALRRVVESQLDLGPIVLFVYYEPSILADPELAAY FDIGDEAIVEVLNRASTERPEYPPGWARRVFWALMQAGYEAAKDGMPRHQIVDAIMTSLT SGIITLPRT
- Number of residues
- 189
- Molecular Weight
- 20618.16
- Theoretical pI
- 5.28
- GO Classification
- FunctionsDNA bindingProcessesregulation of transcription, DNA-templated / transcription, DNA-templated
- General Function
- Dna binding
- Specific Function
- Not Available
- Pfam Domain Function
- TetR_N (PF00440)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0013013|TetR family transcriptional regulator (lfrR) ATGACCAGCCCGAGCATCGAGAGCGGCGCGCGTGAACGCACACGTCGCGCGATCCTTGAT GCCGCCATGCTGGTCCTGGCCGATCACCCCACCGCCGCACTCGGCGACATCGCCGCGGCC GCCGGGGTCGGACGCAGCACGGTGCACCGCTACTACCCGGAGCGCACCGACCTGCTGCGC GCGCTGGCCCGCCACGTCCACGACCTGAGCAACGCCGCGATCGAGCGCGCCGACCCGACC AGCGGTCCTGTCGACGCCGCGCTGCGCCGGGTCGTCGAGAGCCAGCTCGACCTGGGCCCG ATCGTGCTGTTCGTCTACTACGAGCCCTCGATCCTGGCCGATCCTGAACTCGCGGCCTAC TTCGACATCGGGGACGAGGCCATCGTCGAGGTGCTCAACCGCGCGTCGACCGAGAGGCCC GAATATCCCCCAGGGTGGGCGCGACGGGTGTTCTGGGCACTGATGCAGGCCGGTTATGAG GCAGCCAAGGACGGCATGCCGCGTCACCAGATCGTCGACGCCATCATGACCAGCCTGACC TCGGGCATCATCACCCTGCCGCGCACCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q58L87 UniProtKB Entry Name Q58L87_MYCSM GenBank Protein ID 61104877 GenBank Gene ID AY940437 - General References
- Li XZ, Zhang L, Nikaido H: Efflux pump-mediated intrinsic drug resistance in Mycobacterium smegmatis. Antimicrob Agents Chemother. 2004 Jul;48(7):2415-23. [Article]
- Bellinzoni M, Buroni S, Schaeffer F, Riccardi G, De Rossi E, Alzari PM: Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator. J Bacteriol. 2009 Dec;191(24):7531-7. doi: 10.1128/JB.00631-09. Epub 2009 Oct 9. [Article]