Tubulin beta chain

Details

Name
Tubulin beta chain
Synonyms
  • Beta-tubulin
Gene Name
Not Available
Organism
Trichophyton rubrum
Amino acid sequence
>lcl|BSEQ0052806|Tubulin beta chain
MREIVHLQTGQCGNQIGAAFWQTIAGEHGLDGSGHYTGSSDLQLERMNVYFNEASSKKYV
PRAVLVDLEPAALDAVRAGPFGQLFRPDNVVFGQSGAGNNWAKGHYTEGANLVDQVIDVV
RREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPAGMMATFSVVPSPMVSDTVV
EPYNATLSIHQLVEHSDETFCIDNEALYNICMRTLKLTNPSYGDLNHLVSAVMSGVSTSL
RFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRNAYSFRAVSVPELTQQMFDPKNMM
AATDFRSGRYLTCSAIFRGKVSMKEVEDQMRNIQNKNSAYFVEWIPNNVQTALCSIPPRG
LQMSSTFVGNSTSIQELFKRVGDQFTAMFRKKAFLFWYTGEGMDEMEFTEAENNMNDLVS
EYQQYQDASVSDGEEEYLEDEQLEGEE
Number of residues
447
Molecular Weight
49669.63
Theoretical pI
Not Available
GO Classification
Functions
GTP binding / GTPase activity / metal ion binding / structural constituent of cytoskeleton
Processes
microtubule-based process
Components
cytoplasm / microtubule
General Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Specific Function
Gtp binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ5UBX3
UniProtKB Entry NameTBB_TRIRU
General References
Not Available

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00400Griseofulvinapproved, investigational, vet_approvedyesinhibitorDetails