Pol polyprotein
Details
- Name
- Pol polyprotein
- Synonyms
- Not Available
- Gene Name
- pol
- Organism
- SIV-mac
- Amino acid sequence
>lcl|BSEQ0019518|Pol polyprotein VLELWERGTLCKAMQSPKKTGMLEMWKNGPCYGQMPRQTGGFFRPWSMGKEAPQFPHGSS ASGADANCSPRGPSCGSAKELHAVGQAAERKAERKQREALQGGDRGFAAPQFSLWRRPVV TAHIEGQPVEVLLDTGADDSIVTGIELGPHYTPKIVGGIGGFINTKEYKNVEIEVLGKRI KGTIMTGDTPINIFGRNLLTALGMSLNFPIAKVEPVKVALKPGKDGPKLKQWPLSKEKIV ALREICEKMEKDGQLEEAPPTNPYNTPTFAIKKKDKNKWRMLIDFRELNRVTQDFTEVQL GIPHPAGLAKRKRITVLDIGDAYFSIPLDEEFRQYTAFTLPSVNNAEPGKRYIYKVLPQG WKGSPAIFQYTMRHVLEPFRKANPDVTLVQYMDDILIASDRTDLEHDRVVLQSKELLNSI GFSTPEEKFQKDPPFQWMGYELWPTKWKLQKIELPQRETWTVNDIQKLVGVLNWAAQIYP GIKTKHLCRLIRGKMTLTEEVQWTEMAEAEYEENKIILSQEQEGCYYQEGKPLEATVIKS QDNQWSYKIHQEDKILKVGKFAKIKNTHTNGVRLLAHVIQKIGKEAIVIWGQVPKFHLPV EKDVWEQWWTDYWQVTWIPEWDFISTPPLVRLVFNLVKDPIEGEETYYTDGSCNKQSKEG KAGYITDRGKDKVKVLEQTTNQQAELEAFLMALTDSGPKANIIVDSQYVMGIITGCPTES ESRLVNQIIEEMIKKSEIYVAWVPAHKGIGGNQEIDHLVSQGIRQVLFLEKIEPAQEEHD KYHSNVKELVFKFGLPRIVARQIVDTCDKCHQKGEAIHGQANSDLGTWQMDCTHLEGKII IVAVHVASGFIEAEVIPQETGRQTALFLLKLAGRWPITHLHTDNGANFASQEVKMVAWWA GIEHTFGVPYNPQSQGVVEAMNHHLKNQIDRIREQANSVETIVLMAVHCMNFKRRGGIGD MTPAERLINMITTEQEIQFQQSKNSKFKNFRVYYREGRDQLWKGPGELLWKGEGAVILKV GTDIKVVPRRKAKIIKDYGGGKEVDSSSHMEDTGEAREVA
- Number of residues
- 1060
- Molecular Weight
- 120104.205
- Theoretical pI
- 7.9
- GO Classification
- Functionsaspartic-type endopeptidase activity / DNA binding / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / zinc ion bindingProcessesDNA integration / DNA recombination / establishment of integrated proviral latency / viral entry into host cell
- General Function
- Zinc ion binding
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0007760|1533 bp ATGGGCGTGAGAAACTCCGTCTTGTCAGGGAAGAAAGCAGATGAATTAGAAAAAATTAGG CTACGACCCAACGGAAAGAAAAAGTACATGTTGAAGCATGTAGTATGGGCAGCAAATGAA TTAGATAGATTTGGATTAGCAGAAAGCCTGTTGGAGAACAAAGAAGGATGTCAAAAAATA CTTTCGGTCTTAGCTCCATTAGTGCCAACAGGCTCAGAAAATTTAAAAAGCCTTTATAAT ACTGTCTGCGTCATCTGGTGCATTCACGCAGAAGAGAAAGTGAAACACACTGAGGAAGCA AAACAGATAGTGCAGAGACACCTAGTGGTGGAAACAGGAACAACAGAAACTATGCCAAAA ACAAGTAGACCAACAGCACCATCTAGCGGCAGAGGAGGAAATTACCCAGTACAACAAATA GGTGGTAACTATGTCCACCTGCCATTAAGCCCGAGAACATTAAATGCCTGGGTAAAATTG ATAGAGGAAAAGAAATTTGGAGCAGAAGTAGTGCCAGGATTTCAGGCACTGTCAGAAGGT TGCACCCCCTATGACATTAATCAGATGTTAAATTGTGTGGGAGACCATCAAGCGGCTATG CAGATTATCAGAGATATTATAAACGAGGAGGCTGCAGATTGGGACTTGCAGCACCCACAA CCAGCTCCACAACAAGGACAACTTAGGGAGCCGTCAGGATCAGATATTGCAGGAACAACT AGTTCAGTAGATGAACAAATCCAGTGGATGTACAGACAACAGAACCCCATACCAGTAGGC AACATTTACAGGAGATGGATCCAACTGGGGTTGCAAAAATGTGTCAGAATGTATAACCCA ACAAACATTCTAGATGTAAAACAAGGGCCAAAAGAGCCATTTCAGAGCTATGTAGACAGG TTCTACAAAAGTTTAAGAGCAGAACAGACAGATGCAGCAGTAAAGAATTGGATGACTCAA ACACTGCTGATTCAAAATGCTAACCCAGATTGCAAGCTAGTGCTGAAGGGGCTGGGTGTG AATCCCACCCTAGAAGAAATGCTGACGGCTTGTCAAGGAGTAGGGGGGCCGGGACAGAAG GCTAGATTAATGGCAGAAGCCCTGAAAGAGGCCCTCGCACCAGTGCCAATCCCTTTTGCA GCAGCCCAACAGAGGGGACCAAGAAAGCCAATTAAGTGTTGGAATTGTGGGAAAGAGGGA CACTCTGCAAGGCAATGCAGAGCCCCAAGAAGACAGGGATGCTGGAAATGTGGAAAAATG GACCATGTTATGGCCAAATGCCCAGACAGACAGGCGGGTTTTTTAGGCCTTGGTCCATGG GGAAAGAAGCCCCGCAATTTCCCCATGGCTCAAGTGCATCAGGGGCTGATGCCAACTGCT CCCCCAGAGGACCCAGCTGTGGATCTGCTAAAGAACTACATGCAGTTGGGCAAGCAGCAG AGAGAAAAGCAGAGAGAAAGCAGAGAGAAGCCTTACAAGGAGGTGACAGAGGATTTGCTG CACCTCAATTCTCTCTTTGGAGGAGACCAGTAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q88016 UniProtKB Entry Name Q88016_SIVM3 GenBank Protein ID 334650 GenBank Gene ID M33262 - General References
- Kestler H, Kodama T, Ringler D, Marthas M, Pedersen N, Lackner A, Regier D, Sehgal P, Daniel M, King N, et al.: Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus. Science. 1990 Jun 1;248(4959):1109-12. [Article]
- Wilderspin AF, Sugrue RJ: Alternative native flap conformation revealed by 2.3 A resolution structure of SIV proteinase. J Mol Biol. 1994 May 27;239(1):97-103. [Article]