60S ribosomal protein L14, putative

Details

Name

60S ribosomal protein L14, putative

Synonyms

Not Available

Gene Name

Not Available

Organism

Plasmodium falciparum (isolate 3D7)

Amino acid sequence

>lcl|BSEQ0051538|60S ribosomal protein L14, putative
MPRVELTEEEKLYISKKNLLFKRFVEPGRLCLIEYGPYAGKLCFIVDIVTITRVIVDGAF
ITGVPRMVIPLKRLKLLKERIKINKNCKSGFLRKTVNSTKVLEEFNNSKLGKKMIIKKKR
DEATDFERFQVYFAKRELKKKMTTIKNKKNGENKKVKKNVQKVKA

Number of residues

165

Molecular Weight

19297.13

Theoretical pI

Not Available

GO Classification

Functions

RNA binding / structural constituent of ribosome

Processes

ribosomal large subunit biogenesis / translation

Components

cytosolic large ribosomal subunit / cytosolic small ribosomal subunit

General Function

Not Available

Specific Function

Rna binding

Pfam Domain Function

• Ribosomal_L14e (PF01929)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0051539|60S ribosomal protein L14, putative
ATGCCACGAGTTGAATTAACAGAAGAAGAAAAATTATATATTTCTAAAAAAAATCTTTTG
TTTAAAAGATTTGTAGAGCCAGGCAGATTATGCCTTATTGAGTATGGTCCATACGCTGGA
AAGTTATGTTTTATTGTAGATATTGTAACCATCACTCGTGTTATCGTCGATGGAGCATTT
ATTACAGGAGTGCCTCGTATGGTCATCCCCTTGAAAAGATTAAAGTTATTAAAGGAAAGA
ATTAAAATTAACAAAAATTGTAAAAGTGGATTTTTAAGGAAAACAGTTAACAGCACCAAG
GTATTAGAAGAGTTTAATAATTCAAAGTTGGGAAAGAAAATGATCATCAAAAAAAAAAGA
GATGAAGCTACCGACTTCGAAAGATTCCAAGTATATTTTGCCAAGAGAGAATTAAAAAAG
AAAATGACAACCATAAAAAATAAAAAAAATGGTGAAAATAAAAAAGTTAAGAAAAATGTA
CAAAAGGTTAAAGCTTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q8ILE8
UniProtKB Entry Name	Q8ILE8_PLAF7

General References

1. Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
2. Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife. 2014 Jun 9;3. doi: 10.7554/eLife.03080. [Article]
3. Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J: Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res. 2015 Dec 2;43(21):10515-24. doi: 10.1093/nar/gkv991. Epub 2015 Oct 1. [Article]
4. Wong W, Bai XC, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SHW, Baum J: Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol. 2017 Mar 13;2:17031. doi: 10.1038/nmicrobiol.2017.31. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB11638	Artenimol	approved, experimental, investigational	unknown	ligand	Details