60S ribosomal protein L10, putative

Details

Name
60S ribosomal protein L10, putative
Synonyms
Not Available
Gene Name
Not Available
Organism
Plasmodium falciparum (isolate 3D7)
Amino acid sequence
>lcl|BSEQ0051498|60S ribosomal protein L10, putative
MGRRPARCYRYCKNKPYPKSRYCRGVPDPKIRIYDMGRKKADVNEFSGVVHLVSYEYEQI
SSEALEAARISANKYMITNCGKDNFHLRVRIHPFHVLRINKMLSCAGADRLQTGMRGAFG
KPNGVVARVDIGQVLLSIRTKENFVSKACEALRRAKYKFPGRQKVFVSNKWGFTPFSKDE
YQQYKKKGRIISDGVSCKFIREKGPLDKIYKDINTVLES
Number of residues
219
Molecular Weight
25216.14
Theoretical pI
Not Available
GO Classification
Functions
RNA binding / structural constituent of ribosome
Processes
ribosomal large subunit assembly / translation
Components
cytosolic large ribosomal subunit
General Function
Not Available
Specific Function
Rna binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0051499|60S ribosomal protein L10, putative
ATGGGAAGAAGACCAGCAAGGTGTTATAGGTACTGTAAAAATAAACCCTACCCAAAGAGT
CGTTACTGTAGAGGTGTTCCTGACCCTAAGATAAGAATTTATGATATGGGTAGAAAGAAA
GCTGATGTCAATGAATTTAGCGGTGTAGTACATTTAGTATCTTACGAATATGAACAGATA
TCATCTGAAGCTTTAGAAGCTGCACGTATTAGTGCAAACAAATATATGATTACCAATTGT
GGTAAAGATAATTTCCACTTAAGAGTAAGAATACATCCTTTCCACGTTTTAAGAATTAAT
AAGATGTTGTCATGTGCAGGAGCTGATAGACTTCAAACTGGTATGAGAGGAGCCTTCGGT
AAACCTAATGGTGTTGTGGCTAGAGTAGATATTGGTCAAGTGTTACTTTCCATAAGAACT
AAAGAAAATTTCGTTTCAAAAGCTTGTGAAGCCTTAAGAAGAGCTAAATATAAGTTCCCA
GGAAGACAAAAAGTTTTTGTTAGTAATAAATGGGGATTCACACCATTCTCTAAAGATGAG
TATCAACAATATAAAAAAAAAGGAAGAATTATTTCAGATGGTGTTAGTTGTAAATTTATT
AGAGAAAAGGGACCACTTGACAAAATCTACAAAGATATTAATACGGTATTAGAATCATAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ8ILV2
UniProtKB Entry NameQ8ILV2_PLAF7
General References
  1. Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
  2. Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife. 2014 Jun 9;3. doi: 10.7554/eLife.03080. [Article]
  3. Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J: Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res. 2015 Dec 2;43(21):10515-24. doi: 10.1093/nar/gkv991. Epub 2015 Oct 1. [Article]
  4. Wong W, Bai XC, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SHW, Baum J: Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol. 2017 Mar 13;2:17031. doi: 10.1038/nmicrobiol.2017.31. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB11638Artenimolapproved, experimental, investigationalunknownligandDetails