Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
Details
- Name
- Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
- Synonyms
- [Acyl-carrier-protein] malonyltransferase
- 2.3.1.39
- MCT
- Mitochondrial malonyl CoA:ACP acyltransferase
- Mitochondrial malonyltransferase
- MT
- Gene Name
- MCAT
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0007310|Malonyl-CoA-acyl carrier protein transacylase, mitochondrial MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAE AMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISG HQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSN VHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKS CNMQAWKSYSAVDVLQTLEHVDLDPQEPPR
- Number of residues
- 390
- Molecular Weight
- 42961.195
- Theoretical pI
- 8.88
- GO Classification
- Functions[acyl-carrier-protein] S-malonyltransferase activity / poly(A) RNA binding / transferase activityProcessesfatty acid biosynthetic process / metabolic processComponentsmitochondrion
- General Function
- Transferase activity
- Specific Function
- Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias.
- Pfam Domain Function
- Acyl_transf_1 (PF00698)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion
- Gene sequence
>lcl|BSEQ0012657|Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) ATGAGCGTCCGGGTCGCACGGGTAGCGTGGGTCAGGGGCTTGGGCGCCAGCTACCGCCGC GGCGCCTCGAGCTTCCCGGTGCCTCCGCCGGGCGCCCAGGGTGTAGCGGAGCTGCTGCGA GATGCGACCGGGGCGGAGGAGGAGGCGCCCTGGGCGGCGACGGAGCGGCGAATGCCGGGC CAGTGCTCCGTGCTGCTCTTCCCGGGCCAGGGCAGCCAGGTGGTGGGCATGGGCCGCGGT CTGCTCAACTACCCGCGCGTCCGCGAACTCTACGCCGCCGCCCGCCGCGTGCTGGGCTAC GACCTGCTGGAACTGAGCCTGCACGGGCCGCAGGAGACCCTGGACCGCACCGTGCACTGT CAGCCCGCGATCTTCGTGGCATCGCTGGCCGCTGTCGAGAAACTACATCACCTGCAGCCC TCGGTGATTGAGAACTGTGTTGCTGCTGCTGGATTCAGTGTGGGAGAGTTTGCAGCCCTA GTGTTTGCCGGAGCCATGGAATTTGCTGAAGGCTCTACGGTTTCTCCAGAAGAATTCCTC TAA
- Chromosome Location
- 22
- Locus
- 22q13.31
- External Identifiers
Resource Link UniProtKB ID Q8IVS2 UniProtKB Entry Name FABD_HUMAN GenBank Protein ID 8574364 GenBank Gene ID AL359401 HGNC ID HGNC:29622 - General References
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