Choline transporter-like protein 3

Details

Name

Choline transporter-like protein 3

Synonyms

• CTL3
• Solute carrier family 44 member 3

Gene Name

SLC44A3

Organism

Humans

Amino acid sequence

>lcl|BSEQ0037174|Choline transporter-like protein 3
MHCLGAEYLVSAEGAPRQREWRPQIYRKCTDTAWLFLFFLFWTGLVFIMGYSVVAGAAGR
LLFGYDSFGNMCGKKNSPVEGAPLSGQDMTLKKHVFFMNSCNLEVKGTQLNRMALCVSNC
PEEQLDSLEEVQFFANTSGSFLCVYSLNSFNYTHSPKADSLCPRLPVPPSKSFPLFNRCV
PQTPECYSLFASVLINDVDTLHRILSGIMSGRDTILGLCILALALSLAMMFTFRFITTLL
VHIFISLVILGLLFVCGVLWWLYYDYTNDLSIELDTERENMKCVLGFAIVSTGITAVLLV
LIFVLRKRIKLTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSLGTAGAA
QVMEGGQVEYKPLSGIRYMWSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNRSKNDPPD
HPILSSLSILFFYHQGTVVKGSFLISVVRIPRIIVMYMQNALKEQQHGALSRYLFRCCYC
CFWCLDKYLLHLNQNAYTTTAINGTDFCTSAKDAFKILSKNSSHFTSINCFGDFIIFLGK
VLVVCFTVFGGLMAFNYNRAFQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVD
LETNDGSSEKPYFMDQEFLSFVKRSNKLNNARAQQDKHSLRNEEGTELQAIVR

Number of residues

653

Molecular Weight

73782.63

Theoretical pI

7.73

GO Classification

Processes

glycerophospholipid biosynthetic process / phosphatidylcholine biosynthetic process / phospholipid metabolic process / small molecule metabolic process / transmembrane transport

Components

integral component of membrane / plasma membrane

General Function

Not Available

Specific Function

Not Available

Pfam Domain Function

• Choline_transpo (PF04515)

Transmembrane Regions

34-54 213-233 243-263 284-304 334-354 384-404 534-554 563-583

Cellular Location

Membrane

Gene sequence

>lcl|BSEQ0019242|Choline transporter-like protein 3 (SLC44A3)
ATGCACTGCCTGGGCGCCGAGTACCTGGTTTCTGCAGAAGGAGCCCCTAGGCAAAGGGAG
TGGCGACCCCAGATTTATAGGAAATGCACAGATACGGCATGGTTATTCCTGTTCTTTCTC
TTTTGGACTGGTTTGGTGTTTATCATGGGCTACTCGGTGGTGGCTGGAGCCGCGGGAAGA
CTCCTCTTTGGCTATGACAGCTTTGGCAACATGTGTGGCAAGAAGAACTCCCCCGTGGAA
GGGGCCCCTCTTTCAGGGCAGGACATGACCCTAAAAAAACACGTGTTCTTTATGAATTCC
TGCAACCTGGAAGTCAAAGGTACGCAGCTCAACCGCATGGCCCTCTGTGTATCCAACTGC
CCTGAAGAGCAGCTTGACTCCCTGGAAGAGGTCCAGTTCTTTGCAAACACCAGTGGGTCC
TTCCTGTGTGTTTATAGTTTGAATTCCTTCAACTATACCCACAGTCCAAAAGCAGACTCA
CTGTGTCCCAGGCTACCAGTTCCTCCAAGCAAGTCATTTCCCTTATTTAACCGATGTGTC
CCTCAAACACCTGAGTGCTACTCCCTATTTGCATCTGTTTTGATAAATGATGTTGACACC
CTCCACCGAATTCTAAGTGGAATCATGTCGGGAAGAGATACAATCCTTGGCCTGTGTATC
CTCGCATTAGCCTTGTCTTTGGCCATGATGTTTACCTTCAGATTCATCACCACCCTTCTG
GTTCACATTTTCATTTCATTGGTTATTTTGGGATTGTTGTTTGTCTGCGGTGTTTTATGG
TGGCTGTATTATGACTATACCAACGACCTCAGCATAGAATTGGACACAGAAAGGGAAAAT
ATGAAGTGCGTGCTGGGGTTTGCTATCGTATCCACAGGCATCACGGCAGTGCTGCTCGTC
TTGATTTTTGTTCTCAGAAAGAGAATAAAATTGACAGTTGAGCTTTTCCAAATCACAAAT
AAAGCCATCAGCAGTGCTCCCTTCCTGCTGTTCCAGCCACTGTGGACATTTGCCATCCTC
ATTTTCTTCTGGGTCCTCTGGGTGGCTGTGCTGCTGAGCCTGGGAACTGCAGGAGCTGCC
CAGGTTATGGAAGGCGGCCAAGTGGAATATAAGCCCCTTTCGGGCATTCGGTACATGTGG
TCGTACCATTTAATTGGCCTCATCTGGACTAGTGAATTCATCCTTGCGTGCCAGCAAATG
ACTATAGCTGGGGCAGTGGTTACTTGTTATTTCAACAGAAGTAAAAATGATCCTCCTGAT
CATCCCATCCTTTCGTCTCTCTCCATTCTCTTCTTCTACCATCAAGGAACCGTTGTGAAA
GGGTCATTTTTAATCTCTGTGGTGAGGATTCCGAGAATCATTGTCATGTACATGCAAAAC
GCACTGAAAGAACAGCAGCATGGTGCATTGTCCAGGTACCTGTTCCGATGCTGCTACTGC
TGTTTCTGGTGTCTTGACAAATACCTGCTCCATCTCAACCAGAATGCATATACTACAACT
GCTATTAATGGGACAGATTTCTGTACATCAGCAAAAGATGCATTCAAAATCTTGTCCAAG
AACTCAAGTCACTTTACATCTATTAACTGCTTTGGAGACTTCATAATTTTTCTAGGAAAG
GTGTTAGTGGTGTGTTTCACTGTTTTTGGAGGACTCATGGCTTTTAACTACAATCGGGCA
TTCCAGGTGTGGGCAGTCCCTCTGTTATTGGTAGCTTTTTTTGCCTACTTAGTAGCCCAT
AGTTTTTTATCTGTGTTTGAAACTGTGCTGGATGCACTTTTCCTGTGTTTTGCTGTTGAT
CTGGAAACAAATGATGGATCGTCAGAAAAGCCCTACTTTATGGATCAAGAATTTCTGAGT
TTCGTAAAAAGGAGCAACAAATTAAACAATGCAAGGGCACAGCAGGACAAGCACTCATTA
AGGAATGAGGAGGGAACAGAACTCCAGGCCATTGTGAGATAG

Chromosome Location

1

Locus

1p21.3

External Identifiers

Resource	Link
UniProtKB ID	Q8N4M1
UniProtKB Entry Name	CTL3_HUMAN
GenBank Gene ID	AC093429
GenAtlas ID	SLC44A3
HGNC ID	HGNC:28689

General References

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Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB00122	Choline	approved, nutraceutical	unknown	substrate	Details
DB14006	Choline salicylate	approved, nutraceutical	unknown	substrate	Details