V-type proton ATPase subunit C 2
Details
- Name
- V-type proton ATPase subunit C 2
- Synonyms
- V-ATPase subunit C 2
- Vacuolar proton pump subunit C 2
- Gene Name
- ATP6V1C2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052449|V-type proton ATPase subunit C 2 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKL DTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSV VDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEY LVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKA KENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLG NPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVN FQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFH IDLSLLD
- Number of residues
- 427
- Molecular Weight
- 48758.35
- Theoretical pI
- Not Available
- GO Classification
- Functionsidentical protein binding / proton-exporting ATPase activity, phosphorylative mechanism / proton-transporting ATPase activity, rotational mechanismProcessesinsulin receptor signaling pathway / ion transmembrane transport / phagosome acidification / positive regulation of Wnt signaling pathway / regulation of macroautophagy / transferrin transportComponentscell / cytosol / extracellular exosome / lysosomal membrane / vacuolar proton-transporting V-type ATPase, V1 domain
- General Function
- Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
- Specific Function
- Identical protein binding
- Pfam Domain Function
- V-ATPase_C (PF03223)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0052450|V-type proton ATPase subunit C 2 (ATP6V1C2) ATGTCGGAGTTTTGGTTAATTTCTGCCCCTGGCGATAAGGAAAATTTGCAAGCTCTGGAG AGGATGAATACTGTAACCTCCAAGTCCAACCTGTCTTATAATACCAAATTCGCTATTCCT GACTTCAAGGTGGGGACCTTGGATTCCCTGGTTGGCCTCTCTGATGAGTTGGGGAAACTC GACACCTTTGCTGAAAGCCTCATAAGGAGAATGGCTCAGAGCGTGGTGGAAGTCATGGAG GACTCAAAGGGGAAGGTCCAGGAGCACCTCCTGGCAAACGGAGTTGACTTAACATCCTTT GTGACCCACTTTGAATGGGACATGGCCAAATATCCTGTCAAGCAGCCGCTCGTGAGTGTG GTGGACACAATAGCCAAGCAACTGGCGCAGATCGAGATGGACCTGAAGTCCCGAACGGCC GCCTACAACACTCTGAAGACAAACCTGGAGAACCTGGAAAAGAAATCCATGGGGAACCTC TTCACCCGGACACTGAGTGATATTGTGAGCAAAGAGGACTTCGTGCTGGATTCTGAATAT CTCGTCACACTTCTGGTCATCGTCCCCAAACCAAACTACTCACAATGGCAAAAAACCTAC GAATCTCTCTCAGACATGGTGGTCCCTCGATCAACCAAACTCATTACTGAGGACAAGGAA GGGGGCCTTTTCACTGTGACTCTGTTTCGAAAAGTGATTGAAGATTTCAAAACCAAGGCC AAAGAAAACAAGTTCACTGTTCGTGAATTTTACTATGATGAGAAGGAAATTGAAAGGGAA AGGGAGGAGATGGCCAGATTGCTGTCTGATAAGAAGCAACAGTATCAAACTTCCTGTGTT GCTCTTAAAAAGGGATCATCCACCTTCCCGGACCACAAGGTTAAGGTAACCCCGCTAGGT AACCCTGATAGGCCTGCTGCGGGGCAGACCGACAGAGAGAGAGAGAGTGAGGGCGAGGGT GAGGGCCCCCTGCTGCGCTGGCTCAAGGTGAACTTCAGTGAAGCCTTCATTGCCTGGATC CACATCAAGGCCCTGAGAGTGTTTGTGGAGTCCGTGCTCAGGTATGGACTACCAGTGAAC TTCCAGGCAGTGCTCCTGCAGCCGCATAAGAAGTCATCCACCAAGCGTTTAAGAGAGGTT CTAAACTCTGTCTTCCGACATCTGGATGAAGTAGCCGCTACAAGTATACTGGATGCATCT GTGGAGATCCCGGGACTGCAACTCAATAACCAAGACTATTTTCCTTATGTCTACTTCCAT ATTGACCTTAGTCTTCTTGACTAG
- Chromosome Location
- 2
- Locus
- 2p25.1
- External Identifiers
Resource Link UniProtKB ID Q8NEY4 UniProtKB Entry Name VATC2_HUMAN HGNC ID HGNC:18264 - General References
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