Calreticulin-3
Details
- Name
- Calreticulin-3
- Synonyms
- Calreticulin-2
- Calsperin
- CRT2
- Gene Name
- CALR3
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0049521|Calreticulin-3 MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQSTNDSRFGHFRLSSGKFYGHK EKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQK NLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDL SYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWEKHFLDASTSKQ SDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAI GLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREMDAIQAKEEMKKAREEEE EELLSGKINRHEHYFNQFHRRNEL
- Number of residues
- 384
- Molecular Weight
- 44995.345
- Theoretical pI
- Not Available
- GO Classification
- Functionscalcium ion binding / carbohydrate binding / protein binding involved in protein folding / unfolded protein bindingProcessescell differentiation / spermatogenesisComponentsendoplasmic reticulum lumen
- General Function
- During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium-binding may be absent or much lower than that of CALR.
- Specific Function
- Calcium ion binding
- Pfam Domain Function
- Calreticulin (PF00262)
- Transmembrane Regions
- Not Available
- Cellular Location
- Endoplasmic reticulum lumen
- Gene sequence
>lcl|BSEQ0049522|Calreticulin-3 (CALR3) ATGGCCCGGGCTTTGGTCCAGCTCTGGGCCATATGCATGCTGCGAGTGGCGCTGGCTACC GTCTATTTCCAAGAGGAATTTCTAGACGGAGAGCATTGGAGAAACCGATGGTTGCAGTCC ACCAATGACTCCCGATTTGGGCATTTTAGACTTTCGTCGGGCAAGTTTTATGGTCATAAA GAGAAAGATAAAGGTCTGCAAACCACTCAGAATGGCCGATTCTATGCCATCTCTGCACGC TTCAAACCGTTCAGCAATAAAGGGAAAACTCTGGTTATTCAGTACACAGTAAAACATGAG CAGAAGATGGACTGTGGAGGGGGCTACATTAAGGTCTTTCCTGCAGACATTGACCAGAAG AACCTGAATGGAAAATCGCAGTACTATATTATGTTTGGACCCGATATTTGTGGATTTGAT ATCAAGAAAGTTCATGTTATTTTACATTTCAAGAATAAGTATCACGAAAACAAGAAACTG ATCAGGTGTAAGGTTGATGGCTTCACACACCTGTACACTCTAATTTTAAGACCAGATCTT TCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACTGG AACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACT AAAGACAACAAAGCCCAGGACTGGGAGAAGCATTTTCTGGACGCCAGCACCAGCAAGCAG AGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCG TACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATG AAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTTGAGAACATTGGTGCCATT GGCCTGGAGCTTTGGCAGGTGAGATCTGGAACCATTTTTGATAACTTTCTGATCACAGAT GATGAAGAGTACGCAGATAATTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAA AGGGAGATGGATGCCATACAGGCCAAGGAGGAAATGAAGAAGGCCCGCGAGGAAGAGGAG GAAGAGCTGCTGTCGGGAAAAATTAACAGGCACGAACATTACTTCAATCAATTTCACAGA AGGAATGAACTTTAG
- Chromosome Location
- 19
- Locus
- 19p13.11
- External Identifiers
Resource Link UniProtKB ID Q96L12 UniProtKB Entry Name CALR3_HUMAN HGNC ID HGNC:20407 - General References
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