Metal transporter CNNM2
Details
- Name
- Metal transporter CNNM2
- Synonyms
- ACDP2
- Ancient conserved domain-containing protein 2
- Cyclin-M2
- Gene Name
- CNNM2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0049425|Metal transporter CNNM2 MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGA GGCAAVGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAF TEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPL RKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGED TKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKN YAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVP QAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRV TDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTR IPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKK GKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHR ERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQ ELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTA SPVPLSLSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNN QLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLT ELHDGLPDETANLLNEQNCVTHSKANHSLHNEGAI
- Number of residues
- 875
- Molecular Weight
- 96622.35
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / magnesium ion transmembrane transporter activityProcessesmagnesium ion homeostasisComponentsbasolateral plasma membrane / integral component of membrane / intracellular membrane-bounded organelle
- General Function
- Magnesium ion transmembrane transporter activity
- Specific Function
- Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
- Pfam Domain Function
- Transmembrane Regions
- 251-271 339-359 369-389
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0049426|Metal transporter CNNM2 (CNNM2) ATGATTGGCTGTGGCGCTTGTGAACCCAAAGTAAAGATGGCGGGCGGGCAGGCAGCCGCC GCACTGCCCACTTGGAAGATGGCGGCGCGCCGCAGCCTCAGCGCTCGCGGCCGGGGGATC CTGCAGGCGGCTGCGGGGCGGCTGCTGCCGCTGCTCCTGCTGAGCTGCTGCTGCGGTGCG GGCGGCTGCGCAGCGGTGGGCGAGAATGAGGAGACGGTGATCATCGGGCTGCGACTGGAG GACACGAACGACGTGTCGTTCATGGAAGGGGGGGCGCTGCGGGTGAGCGAACGGACCCGG GTCAAGCTGCGGGTGTACGGGCAGAACATCAATAACGAGACGTGGTCCCGCATCGCCTTC ACCGAGCACGAGCGGCGGCGCCACAGCCCGGGGGAGCGCGGGCTGGGGGGCCCCGCGCCG CCAGAGCCGGACAGCGGCCCCCAGCGATGCGGCATCCGCACCTCAGACATCATCATCTTG CCCCACATCATTCTCAACCGCCGCACCTCGGGCATCATCGAGATCGAGATCAAACCGCTA CGCAAGATGGAGAAGAGCAAGTCCTATTACCTGTGCACGTCGCTCTCCACGCCCGCCCTG GGCGCCGGCGGCTCGGGGTCCACGGGTGGCGCCGTCGGGGGCAAGGGTGGCTCGGGGGTG GCCGGGCTCCCGCCGCCCCCGTGGGCCGAGACCACCTGGATTTACCACGACGGCGAGGAC ACCAAGATGATCGTAGGCGAAGAGAAGAAGTTCCTGCTGCCCTTCTGGCTGCAGGTGATC TTCATTTCGCTGCTGCTGTGCCTGTCGGGCATGTTCAGCGGCCTCAACCTGGGGCTCATG GCCCTGGACCCGATGGAGCTGCGCATCGTGCAGAACTGCGGCACGGAGAAGGAGAAGAAT TACGCCAAGCGCATCGAGCCGGTGCGCAGGCAGGGCAACTACCTGCTGTGCTCACTGCTG CTGGGCAACGTGCTGGTCAACACCACGCTCACCATCCTGCTCGACGACATCGCCGGCTCG GGCCTCGTGGCCGTGGTAGTCTCCACCATCGGTATCGTCATCTTCGGAGAGATCGTGCCC CAGGCCATCTGCTCCCGGCATGGCCTGGCTGTGGGGGCCAACACCATCTTCCTCACCAAG TTTTTCATGATGATGACCTTCCCCGCTTCCTACCCGGTCAGCAAGCTGCTGGACTGCGTC CTGGGCCAGGAGATAGGCACCGTCTATAACCGGGAAAAACTGCTGGAGATGCTCCGGGTC ACCGATCCCTACAACGACCTCGTTAAGGAGGAGCTGAACATCATCCAAGGGGCGCTGGAG CTCCGCACCAAGACGGTGGAGGACGTGATGACCCCACTCCGGGACTGCTTCATGATCACC GGCGAAGCCATCCTGGACTTCAACACCATGTCTGAGATCATGGAGAGCGGCTACACCCGC ATTCCAGTGTTTGAAGGGGAGCGCTCCAATATCGTGGACCTGCTGTTTGTCAAAGACTTG GCCTTCGTGGATCCCGATGACTGTACCCCCCTGAAAACCATCACCAAATTTTATAACCAC CCCTTGCACTTTGTTTTCAATGACACCAAGTTGGACGCTATGCTGGAAGAATTTAAGAAA GGTAAATCTCACCTGGCTATCGTGCAGCGGGTAAACAATGAGGGAGAAGGGGATCCATTT TATGAAGTTCTGGGAATCGTCACCTTAGAAGATGTGATTGAAGAAATCATCAAATCTGAG ATTCTTGATGAAACAGATTTATACACTGACAACAGAACGAAAAAGAAAGTGGCTCACCGG GAACGAAAGCAAGATTTTTCTGCCTTTAAGCAGACAGACAGTGAGATGAAGGTTAAAATA TCACCACAGCTCCTCCTGGCCATGCACCGTTTCCTAGCAACAGAAGTAGAAGCATTTAGC CCATCCCAGATGTCAGAGAAGATCCTTCTAAGGCTGCTAAAGCACCCCAATGTCATCCAG GAACTGAAATATGATGAGAAGAACAAGAAAGCCCCCGAATACTACCTCTACCAGCGCAAC AAGCCAGTAGACTACTTCGTTCTCATTCTGCAGGGGAAAGTGGAAGTTGAAGCTGGGAAA GAAGGTATGAAGTTTGAAGCGAGCGCCTTCTCATACTATGGCGTGATGGCCCTGACAGCC TCTCCAGTTCCTTTGTCCCTGTCTCGTACCTTTGTTGTCAGCAGAACAGAGTTGTTAGCA GCAGGTTCTCCAGGTGAAAATAAGTCCCCTCCTCGCCCATGTGGCTTGAATCACTCAGAC TCTCTCAGTCGAAGCGACCGGATTGACGCCGTCACACCAACACTGGGGAGCAGCAATAAC CAGCTCAATTCTTCGCTCCTCCAAGTCTACATCCCCGATTACTCGGTGCGAGCCCTTTCG GATCTGCAGTTTGTTAAGATCTCAAGACAGCAATACCAAAATGCCTTGATGGCATCCCGG ATGGACAAAACCCCCCAGTCTTCAGACAGTGAAAACACTAAAATCGAATTGACTCTTACG GAGCTGCATGACGGGTTGCCAGACGAGACAGCCAACCTGCTCAACGAACAGAACTGTGTG ACGCACAGTAAGGCCAACCACAGCCTGCACAACGAAGGCGCCATCTAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9H8M5 UniProtKB Entry Name CNNM2_HUMAN HGNC ID HGNC:103 - General References
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