Retinoid-inducible serine carboxypeptidase

Details

Name
Retinoid-inducible serine carboxypeptidase
Synonyms
  • 3.4.16.-
  • RISC
  • SCP1
  • Serine carboxypeptidase 1
Gene Name
SCPEP1
Organism
Humans
Amino acid sequence
>lcl|BSEQ0007592|Retinoid-inducible serine carboxypeptidase
MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRKDAYMFWWLYYATN
SCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDSDLKPRKTTWLQAASLLFVDNPVGT
GFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGGKMAAGIGLEL
YKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAEVSKVAEQVLNA
VNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFTQSHLVCLCQRH
VRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPVISIVDELLEAG
INVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSLETSAFVKSYKN
LAFYWILKAGHMVPSDQGDMALKMMRLVTQQE
Number of residues
452
Molecular Weight
50830.325
Theoretical pI
5.53
GO Classification
Functions
serine-type carboxypeptidase activity
Processes
negative regulation of blood pressure / positive regulation of vasodilation / proteolysis involved in cellular protein catabolic process / retinoic acid metabolic process
Components
cytosol / extracellular exosome
General Function
Serine-type carboxypeptidase activity
Specific Function
May be involved in vascular wall and kidney homeostasis.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Secreted
Gene sequence
>lcl|BSEQ0020732|Retinoid-inducible serine carboxypeptidase (SCPEP1)
ATGGAGCTGGCACTGCGGCGCTCTCCCGTCCCGCGGTGGTTGCTGCTGCTGCCGCTGCTG
CTGGGCCTGAACGCAGGAGCTGTCATTGACTGGCCCACAGAGGAGGGCAAGGAAGTATGG
GATTATGTGACGGTCCGCAAGGATGCCTACATGTTCTGGTGGCTCTATTATGCCACCAAC
TCCTGCAAGAACTTCTCAGAACTGCCCCTGGTCATGTGGCTTCAGGGCGGTCCAGGCGGT
TCTAGCACTGGATTTGGAAACTTTGAGGAAATTGGGCCCCTTGACAGTGATCTCAAACCA
CGGAAAACCACCTGGCTCCAGGCTGCCAGTCTCCTATTTGTGGATAATCCCGTGGGCACT
GGGTTCAGTTATGTGAATGGTAGTGGTGCCTATGCCAAGGACCTGGCTATGGTGGCTTCA
GACATGATGGTTCTCCTGAAGACCTTCTTCAGTTGCCACAAAGAATTCCAGACAGTTCCA
TTCTACATTTTCTCAGAGTCCTATGGAGGAAAAATGGCAGCTGGCATTGGTCTAGAGCTT
TATAAGGCCATTCAGCGAGGGACCATCAAGTGCAACTTTGCGGGGGTTGCCTTGGGTGAT
TCCTGGATCTCCCCTGTTGATTCGGTGCTCTCCTGGGGACCTTACCTGTACAGCATGTCT
CTTCTCGAAGACAAAGGTCTGGCAGAGGTGTCTAAGGTTGCAGAGCAAGTACTGAATGCC
GTAAATAAGGGGCTCTACAGAGAGGCCACAGAGCTGTGGGGGAAAGCAGAAATGATCATT
GAACAGAACACAGATGGGGTGAACTTCTATAACATCTTAACTAAAAGCACTCCCACGTCT
ACAATGGAGTCGAGTCTAGAATTCACACAGAGCCACCTAGTTTGTCTTTGTCAGCGCCAC
GTGAGACACCTACAACGAGATGCCTTAAGCCAGCTCATGAATGGCCCCATCAGAAAGAAG
CTCAAAATTATTCCTGAGGATCAATCCTGGGGAGGCCAGGCTACCAACGTCTTTGTGAAC
ATGGAGGAGGACTTCATGAAGCCAGTCATTAGCATTGTGGACGAGTTGCTGGAGGCAGGG
ATCAACGTGACGGTGTATAATGGACAGCTGGATCTCATCGTAGATACCATGGGTCAGGAG
GCCTGGGTGCGGAAACTGAAGTGGCCAGAACTGCCTAAATTCAGTCAGCTGAAGTGGAAG
GCCCTGTACAGTGACCCTAAATCTTTGGAAACATCTGCTTTTGTCAAGTCCTACAAGAAC
CTTGCTTTCTACTGGATTCTGAAAGCTGGTCATATGGTTCCTTCTGACCAAGGGGACATG
GCTCTGAAGATGATGAGACTGGTGACTCAGCAAGAATAG
Chromosome Location
17
Locus
17q22
External Identifiers
ResourceLink
UniProtKB IDQ9HB40
UniProtKB Entry NameRISC_HUMAN
GenBank Protein ID10312169
GenBank Gene IDAF282618
HGNC IDHGNC:29507
General References
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  4. Zhang Z, Henzel WJ: Signal peptide prediction based on analysis of experimentally verified cleavage sites. Protein Sci. 2004 Oct;13(10):2819-24. Epub 2004 Aug 31. [Article]
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB07506L-BENZYLSUCCINIC ACIDexperimentalunknownDetails