G-protein coupled receptor 35
Details
- Name
- G-protein coupled receptor 35
- Synonyms
- KYNA receptor
- Kynurenic acid receptor
- Gene Name
- GPR35
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009310|G-protein coupled receptor 35 MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS QDSLCVTLA
- Number of residues
- 309
- Molecular Weight
- 34071.89
- Theoretical pI
- Not Available
- GO Classification
- FunctionsG-protein coupled receptor activityProcessesG-protein coupled receptor signaling pathwayComponentsintegral component of plasma membrane
- General Function
- G-protein coupled receptor activity
- Specific Function
- Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
- Pfam Domain Function
- 7tm_1 (PF00001)
- Transmembrane Regions
- 25-45 57-77 91-112 136-156 175-195 219-239 259-279
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0019760|G-protein coupled receptor 35 (GPR35) ATGCTGAGTGGTTCCCGGGCTGTCCCCACTCCACACCGTGGCAGTGAAGAGCTGCTGAAG TACATGCTTCATAGTCCTTGCGTCTCTCTGACCATGAATGGCACCTACAACACCTGTGGC TCCAGCGACCTCACCTGGCCCCCAGCGATCAAGCTGGGCTTCTACGCCTACTTGGGCGTC CTGCTGGTGCTAGGCCTGCTGCTCAACAGCCTGGCGCTCTGGGTGTTCTGCTGCCGCATG CAGCAGTGGACGGAGACCCGCATCTACATGACCAACCTGGCGGTGGCCGACCTCTGCCTG CTGTGCACCTTGCCCTTCGTGCTGCACTCCCTGCGAGACACCTCAGACACGCCGCTGTGC CAGCTCTCCCAGGGCATCTACCTGACCAACAGGTACATGAGCATCAGCCTGGTCACGGCC ATCGCCGTGGACCGCTATGTGGCCGTGCGGCACCCGCTGCGTGCCCGCGGGCTGCGGTCC CCCAGGCAGGCTGCGGCCGTGTGCGCGGTCCTCTGGGTGCTGGTCATCGGCTCCCTGGTG GCTCGCTGGCTCCTGGGGATTCAGGAGGGCGGCTTCTGCTTCAGGAGCACCCGGCACAAT TTCAACTCCATGGCGTTCCCGCTGCTGGGATTCTACCTGCCCCTGGCCGTGGTGGTCTTC TGCTCCCTGAAGGTGGTGACTGCCCTGGCCCAGAGGCCACCCACCGACGTGGGGCAGGCA GAGGCCACCCGCAAGGCTGCCCGCATGGTCTGGGCCAACCTCCTGGTGTTCGTGGTCTGC TTCCTGCCCCTGCACGTGGGGCTGACAGTGCGCCTCGCAGTGGGCTGGAACGCCTGTGCC CTCCTGGAGACGATCCGTCGCGCCCTGTACATAACCAGCAAGCTCTCAGATGCCAACTGC TGCCTGGACGCCATCTGCTACTACTACATGGCCAAGGAGTTCCAGGAGGCGTCTGCACTG GCCGTGGCTCCCAGTGCTAAGGCCCACAAAAGCCAGGACTCTCTGTGCGTGACCCTCGCC TAA
- Chromosome Location
- 2
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9HC97 UniProtKB Entry Name GPR35_HUMAN HGNC ID HGNC:4492 - General References
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