Protein-tyrosine-phosphatase
Details
- Name
- Protein-tyrosine-phosphatase
- Synonyms
- EC 3.1.3.48
- Gene Name
- PPI
- Organism
- Shewanella sp.
- Amino acid sequence
>lcl|BSEQ0016959|Protein-tyrosine-phosphatase MNKIYCLAVLSLTLLSPLALANTATEFDGPYVITPISGQSTAYWICDNRLKTTSIEKLQV NRPEHCGDLPETKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGN WAFGEGHMVMTGDIFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRY VHQRYDIATTLINRPYNKLYGADTEIGQWLRSKNTIIKINDVLYMHGGISSEWISRELTL DKANALYRANVDASKKSLKADDLLNFLFFGNGPTWYRGYFSETFTEAELDTILQHFNVNH IVVGHTSQERVLGLFHNKVIAVDSSIKVGKSGELLLLENNRLIRGLYDGTRETLQENSLN Q
- Number of residues
- 361
- Molecular Weight
- 40814.26
- Theoretical pI
- 6.38
- GO Classification
- Functionsmetal ion binding / protein tyrosine phosphatase activity
- General Function
- Protein tyrosine phosphatase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Metallophos (PF00149)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0005865|1086 bp ATGAATAAAATTTATTGCCTTGCAGTACTGAGTCTAACGCTGCTGAGCCCACTTGCACTT GCCAATACTGCAACTGAGTTTGATGGCCCTTACGTGATAACACCGATATCTGGTCAAAGC ACGGCTTACTGGATCTGTGACAATAGACTCAAAACGACCTCGATAGAAAAGCTGCAAGTA AATCGACCCGAGCATTGTGGGGATTTACCCGAGACTAAGCTCTCAAGCGAGATTAAGCAG ATCATGCCTGACACTTACTTAGGTATTAAAAAGGTGGTCGCGTTAAGTGATGTACACGGC CAGTATGACGTTCTGCTGACTCTGCTTAAAAAGCAAAAGATTATTGATAGTGATGGAAAT TGGGCCTTCGGCGAGGGGCATATGGTGATGACGGGGGATATCTTTGACCGCGGCCATCAA GTCAATGAAGTGCTGTGGTTTATGTATCAGCTCGACCAACAAGCACGAGACGCTGGCGGC ATGGTACATCTATTAATGGGCAATCATGAACAGATGGTACTCGGCGGTGACTTGCGCTAT GTACACCAGCGTTATGATATAGCCACAACCCTCATTAACCGCCCCTATAACAAGCTCTAC GGCGCAGATACTGAAATAGGTCAGTGGTTAAGAAGTAAGAACACCATTATCAAGATCAAC GATGTGCTGTATATGCATGGTGGGATCAGCAGCGAATGGATCAGTCGAGAGCTAACCTTA GACAAAGCGAATGCACTGTATCGAGCTAATGTGGATGCGTCGAAAAAATCACTAAAGGCG GATGACTTACTCAATTTCCTTTTTTTTGGAAACGGACCAACTTGGTATCGAGGCTACTTT TCAGAAACATTTACCGAAGCTGAACTGGATACCATTTTACAACACTTTAACGTTAATCAT ATCGTGGTCGGACACACCTCCCAAGAACGGGTCTTAGGTCTATTCCACAACAAAGTCATT GCCGTCGATAGCAGCATAAAAGTCGGTAAATCAGGTGAACTGCTATTACTGGAAAATAAC CGGCTTATACGCGGGTTATATGACGGAACACGTGAAACACTGCAGGAAAATAGCCTTAAT CAATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9S427 UniProtKB Entry Name Q9S427_9GAMM GenBank Gene ID AF164202 - General References
- Tsuruta H, Mikami B, Aizono Y: Crystal structure of cold-active protein-tyrosine phosphatase from a psychrophile, Shewanella sp. J Biochem. 2005 Jan;137(1):69-77. [Article]
- Tsuruta H, Mikami B, Yamamoto C, Yamagata H: The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase. FEBS J. 2008 Sep;275(17):4317-28. doi: 10.1111/j.1742-4658.2008.06575.x. Epub 2008 Jul 18. [Article]
Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details