Ganciclovir sodiumProduct ingredient for Ganciclovir

Show full entry for Ganciclovir
Name
Ganciclovir sodium
Drug Entry
Ganciclovir

An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

See full entry for Ganciclovir
Accession Number
DBSALT000309
Structure
Similar Structures
Synonyms
Not Available
UNII
02L083W284
CAS Number
107910-75-8
Weight
Average: 277.2124
Monoisotopic: 277.078698572
Chemical Formula
C9H12N5NaO4
InChI Key
JJICLMJFIKGAAU-UHFFFAOYSA-M
InChI
InChI=1S/C9H13N5O4.Na/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);/q;+1/p-1
IUPAC Name
sodium 9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-2-imino-3,9-dihydro-2H-purin-6-olate
SMILES
[Na+].OCC(CO)OCN1C=NC2=C1NC(=N)N=C2[O-]
PubChem Compound
23700083
ChemSpider
54279
ChEBI
774801
ChEMBL
CHEMBL1200850
Wikipedia
Ganciclovir
Predicted Properties
PropertyValueSource
Water Solubility7.95 mg/mLALOGPS
logP-1.5ALOGPS
logP-3.1Chemaxon
logS-1.5ALOGPS
pKa (Strongest Acidic)-6.3Chemaxon
pKa (Strongest Basic)20.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count8Chemaxon
Hydrogen Donor Count4Chemaxon
Polar Surface Area138.81 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity82.16 m3·mol-1Chemaxon
Polarizability23.95 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon