Risedronate sodiumProduct ingredient for Risedronic acid

Name
Risedronate sodium
Drug Entry
Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's diseaseLabel1,2. It functions by preventing resorption of boneLabel1.

Accession Number
DBSALT000494
Structure
Synonyms
Not Available
UNII
OFG5EXG60L
CAS Number
115436-72-1
Weight
Average: 305.0941
Monoisotopic: 304.983019378
Chemical Formula
C7H10NNaO7P2
InChI Key
DRFDPXKCEWYIAW-UHFFFAOYSA-M
InChI
InChI=1S/C7H11NO7P2.Na/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);/q;+1/p-1
IUPAC Name
sodium hydrogen [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonate
SMILES
[Na+].OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)([O-])=O
PubChem Compound
4194514
ChemSpider
61985
ChEBI
8868
ChEMBL
CHEMBL1654
Wikipedia
Risedronic_acid
Predicted Properties
PropertyValueSource
Water Solubility16.5 mg/mLALOGPS
logP-0.59ALOGPS
logP-3.3Chemaxon
logS-1.3ALOGPS
pKa (Strongest Acidic)0.68Chemaxon
pKa (Strongest Basic)4.91Chemaxon
Physiological Charge-3Chemaxon
Hydrogen Acceptor Count8Chemaxon
Hydrogen Donor Count4Chemaxon
Polar Surface Area151.01 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity56 m3·mol-1Chemaxon
Polarizability21.25 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon