Moricizine hydrochlorideProduct ingredient for Moricizine

Name
Moricizine hydrochloride
Drug Entry
Moricizine

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.

Accession Number
DBSALT000994
Structure
Synonyms
moricizine HCl
UNII
71OK3Z1ESP
CAS Number
29560-58-5
Weight
Average: 463.98
Monoisotopic: 463.1332552
Chemical Formula
C22H26ClN3O4S
InChI Key
GAQAKFHSULJNAK-UHFFFAOYSA-N
InChI
InChI=1S/C22H25N3O4S.ClH/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24;/h3-8,15H,2,9-14H2,1H3,(H,23,27);1H
IUPAC Name
N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}ethoxycarboximidic acid hydrochloride
SMILES
Cl.CCOC(O)=NC1=CC2=C(SC3=CC=CC=C3N2C(=O)CCN2CCOCC2)C=C1
ChemSpider
31871
ChEBI
60937
ChEMBL
CHEMBL1200334
Wikipedia
Moracizine
Predicted Properties
PropertyValueSource
Water Solubility0.0452 mg/mLALOGPS
logP2.83ALOGPS
logP1.11Chemaxon
logS-4ALOGPS
pKa (Strongest Acidic)3.34Chemaxon
pKa (Strongest Basic)6.77Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area74.6 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity119.9 m3·mol-1Chemaxon
Polarizability45.99 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon