Metaraminol bitartrateProduct ingredient for Metaraminol

Name
Metaraminol bitartrate
Drug Entry
Metaraminol

An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine. It has been used primarily as a vasoconstrictor in the treatment of hypotension.

Accession Number
DBSALT001017  (DBSALT001016)
Structure
Synonyms
Metaraminol tartrate
UNII
ZC4202M9P3
CAS Number
33402-03-8
Weight
Average: 317.294
Monoisotopic: 317.111066576
Chemical Formula
C13H19NO8
InChI Key
VENXSELNXQXCNT-IJYXXVHRSA-N
InChI
InChI=1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1
IUPAC Name
(2R,3R)-2,3-dihydroxybutanedioic acid; 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol
SMILES
O[C@H]([C@@H](O)C(O)=O)C(O)=O.C[C@H](N)[C@H](O)C1=CC=CC(O)=C1
ChemSpider
390149
ChEBI
6795
Wikipedia
Metaraminol
Predicted Properties
PropertyValueSource
Water Solubility12.8 mg/mLALOGPS
logP-0.59ALOGPS
logP-0.045Chemaxon
logS-1.1ALOGPS
pKa (Strongest Acidic)9.03Chemaxon
pKa (Strongest Basic)9.68Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area66.48 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity46.89 m3·mol-1Chemaxon
Polarizability17.86 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon