Loxoprofen sodiumProduct ingredient for Loxoprofen
- Name
- Loxoprofen sodium
- Drug Entry
- Loxoprofen
Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
- Accession Number
- DBSALT001264
- Structure
Structure for Loxoprofen sodium (DBSALT001264)
- Synonyms
- Not Available
- UNII
- NDC2M7399S
- CAS Number
- 80382-23-6
- Weight
- Average: 268.288
Monoisotopic: 268.10753869 - Chemical Formula
- C15H17NaO3
- InChI Key
- WORCCYVLMMTGFR-UHFFFAOYSA-M
- InChI
- InChI=1S/C15H18O3.Na/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);/q;+1/p-1
- IUPAC Name
- sodium 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoate
- SMILES
- [Na+].CC(C([O-])=O)C1=CC=C(CC2CCCC2=O)C=C1
- External Links
- ChemSpider
- 5293207
- ChEBI
- 76198
- ChEMBL
- CHEMBL66552
- Predicted Properties
Property Value Source Water Solubility 0.0268 mg/mL ALOGPS logP 2.96 ALOGPS logP 3.35 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 4.19 Chemaxon pKa (Strongest Basic) -7.4 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 57.2 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 79.64 m3·mol-1 Chemaxon Polarizability 26.65 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon