Fimasartan potassium trihydrateProduct ingredient for Fimasartan
- Name
- Fimasartan potassium trihydrate
- Drug Entry
- Fimasartan
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand name Kanarb by Boryung Pharmaceuticals.
- Accession Number
- DBSALT001281
- Structure
Structure for Fimasartan potassium trihydrate (DBSALT001281)
- Synonyms
- Not Available
- UNII
- 4516BN0T4B
- CAS Number
- 1020110-23-9
- Weight
- Average: 593.79
Monoisotopic: 593.21865533 - Chemical Formula
- C27H36KN7O4S
- InChI Key
- IJEKJHQBGZFMMI-UHFFFAOYSA-N
- InChI
- InChI=1S/C27H30N7OS.K.3H2O/c1-5-6-11-24-28-18(2)23(16-25(36)33(3)4)27(35)34(24)17-19-12-14-20(15-13-19)21-9-7-8-10-22(21)26-29-31-32-30-26;;;;/h7-10,12-15H,5-6,11,16-17H2,1-4H3;;3*1H2/q-1;+1;;;
- IUPAC Name
- potassium 5-[4'-({2-butyl-5-[(dimethylcarbamothioyl)methyl]-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl}methyl)-[1,1'-biphenyl]-2-yl]-1H-1,2,3,4-tetrazol-1-ide trihydrate
- SMILES
- O.O.O.[K+].CCCCC1=NC(C)=C(CC(=S)N(C)C)C(=O)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NN=N[N-]1
- External Links
- ChemSpider
- 28497172
- ChEMBL
- CHEMBL1951146
- Predicted Properties
Property Value Source Water Solubility 0.00542 mg/mL ALOGPS logP 4.03 ALOGPS logP 4.21 Chemaxon logS -5 ALOGPS pKa (Strongest Acidic) 4.23 Chemaxon pKa (Strongest Basic) 1.34 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 87.47 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 161.85 m3·mol-1 Chemaxon Polarizability 54.61 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon