Raxatrigine HydrochlorideProduct ingredient for Vixotrigine
- Name
- Raxatrigine Hydrochloride
- Drug Entry
- Vixotrigine
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
- Accession Number
- DBSALT002054
- Structure
Structure for Raxatrigine Hydrochloride (DBSALT002054)
- Synonyms
- Not Available
- UNII
- 7L3OLR4M8T
- CAS Number
- 934240-31-0
- Weight
- Average: 350.82
Monoisotopic: 350.1197338 - Chemical Formula
- C18H20ClFN2O2
- InChI Key
- HEPUBAGOKRIZEO-PPPUBMIESA-N
- InChI
- InChI=1S/C18H19FN2O2.ClH/c19-15-4-2-1-3-13(15)11-23-14-7-5-12(6-8-14)16-9-10-17(21-16)18(20)22;/h1-8,16-17,21H,9-11H2,(H2,20,22);1H/t16-,17+;/m1./s1
- IUPAC Name
- (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide hydrochloride
- SMILES
- Cl.NC(=O)[C@@H]1CC[C@@H](N1)C1=CC=C(OCC2=CC=CC=C2F)C=C1
- External Links
- ChemSpider
- 13174480
- ChEMBL
- CHEMBL3544912
- Predicted Properties
Property Value Source Water Solubility 0.0142 mg/mL ALOGPS logP 2.43 ALOGPS logP 2.59 Chemaxon logS -4.4 ALOGPS pKa (Strongest Acidic) 15.69 Chemaxon pKa (Strongest Basic) 8.84 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 64.35 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 85.46 m3·mol-1 Chemaxon Polarizability 32.79 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon