Sapanisertib HydrochlorideProduct ingredient for Sapanisertib
- Name
- Sapanisertib Hydrochloride
- Drug Entry
- Sapanisertib
Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.
- Accession Number
- DBSALT002090
- Structure
Structure for Sapanisertib Hydrochloride (DBSALT002090)
- Synonyms
- Not Available
- UNII
- 9T2Z08R92D
- CAS Number
- 1422006-46-9
- Weight
- Average: 346.8
Monoisotopic: 346.1183109 - Chemical Formula
- C15H17ClN7O
- InChI Key
- BIIIFXZHOONGOL-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H16N7O.ClH/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10;/h3-7,20H,17H2,1-2H3,(H2,16,18,19);1H
- IUPAC Name
- 5-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-3H-1lambda3,3-benzoxazol-2-amine hydrochloride
- SMILES
- Cl.CC(C)N1N=C(C2=C(N)N=CN=C12)C1=CC=C2[O]=C(N)NC2=C1
- External Links
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.23 mg/mL ALOGPS logP 1.31 ALOGPS logS -2.4 ALOGPS Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 141.81 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 111.48 m3·mol-1 Chemaxon Polarizability 33.12 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon