Dimazole dihydrochlorideProduct ingredient for Dimazole
- Name
- Dimazole dihydrochloride
- Drug Entry
- Dimazole
Dimazole (diamthazole) is an antifungal. It was withdrawn in Franch in 1972 due to neuropsychiatric reactions.
- Accession Number
- DBSALT002640
- Structure
Structure for Dimazole dihydrochloride (DBSALT002640)
- Synonyms
- Diamthazole dihydrochlroide / Ro 2-2453
- UNII
- 3LF09TBB5W
- CAS Number
- 136-96-9
- Weight
- Average: 366.35
Monoisotopic: 365.109539 - Chemical Formula
- C15H25Cl2N3OS
- InChI Key
- FZNXAQMQVKBXDR-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H23N3OS.2ClH/c1-5-18(6-2)9-10-19-12-7-8-13-14(11-12)20-15(16-13)17(3)4;;/h7-8,11H,5-6,9-10H2,1-4H3;2*1H
- IUPAC Name
- 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine dihydrochloride
- SMILES
- Cl.Cl.CCN(CC)CCOC1=CC2=C(C=C1)N=C(S2)N(C)C
- External Links
- ChemSpider
- 8383
- ChEBI
- 31474
- ChEMBL
- CHEMBL346235
- Predicted Properties
Property Value Source Water Solubility 0.139 mg/mL ALOGPS logP 3.57 ALOGPS logP 3.48 Chemaxon logS -3.3 ALOGPS pKa (Strongest Basic) 9.28 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 28.6 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 85.01 m3·mol-1 Chemaxon Polarizability 34.16 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon