Clocapramine hydrochlorideProduct ingredient for Clocapramine
- Name
- Clocapramine hydrochloride
- Drug Entry
- Clocapramine
Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been implicated in at least one strange death, including a suicide.
- Accession Number
- DBSALT002792
- Structure
Structure for Clocapramine hydrochloride (DBSALT002792)
- Synonyms
- Clocapramine dihydrochloride monohydrate / Clocapramine HCl / Clocapramine hydrochloride hydrate
- External IDs
- Y 4153 / Y-4153
- UNII
- 9NLU6H3LRD
- CAS Number
- 60789-62-0
- Weight
- Average: 572.01
Monoisotopic: 570.2295097 - Chemical Formula
- C28H41Cl3N4O2
- InChI Key
- SWCNPPOGIXOVAZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C28H37ClN4O.2ClH.H2O/c29-24-12-11-23-10-9-22-7-2-3-8-25(22)33(26(23)21-24)18-6-15-31-19-13-28(14-20-31,27(30)34)32-16-4-1-5-17-32;;;/h2-3,7-8,11-12,21H,1,4-6,9-10,13-20H2,(H2,30,34);2*1H;1H2
- IUPAC Name
- 1'-(3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)-[1,4'-bipiperidine]-4'-carboximidic acid hydrate dihydrochloride
- SMILES
- O.Cl.Cl.OC(=N)C1(CCN(CCCN2C3=CC=CC=C3CCC3=C2C=C(Cl)C=C3)CC1)N1CCCCC1
- External Links
- ChemSpider
- 4445642
- Predicted Properties
Property Value Source Water Solubility 0.0055 mg/mL ALOGPS logP 4.69 ALOGPS logP 2.83 Chemaxon logS -4.9 ALOGPS pKa (Strongest Acidic) -4 Chemaxon pKa (Strongest Basic) 13.07 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 53.8 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 151.89 m3·mol-1 Chemaxon Polarizability 55.32 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon