405
  Mrv0541 02231214392D          

 19 20  0  0  1  0            999 V2000
    3.7935   -2.8876    0.0000 Br  0  0  0  0  0  0  0  0  0  0  0  0
    2.3645    2.0625    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080    1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935    0.4125    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    3.0791    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2224    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645    2.8876    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9370    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.2224    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.9370    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1 17  1  0  0  0  0
  2  6  1  0  0  0  0
  2 12  1  0  0  0  0
  2 13  1  0  0  0  0
  3  8  1  0  0  0  0
  3 18  2  0  0  0  0
  4  5  1  6  0  0  0
  4  7  1  0  0  0  0
  4  8  1  0  0  0  0
  5  6  1  0  0  0  0
  7  9  2  0  0  0  0
  7 10  1  0  0  0  0
  8 11  2  0  0  0  0
  9 14  1  0  0  0  0
 10 15  2  0  0  0  0
 11 16  1  0  0  0  0
 14 17  2  0  0  0  0
 15 17  1  0  0  0  0
 16 19  2  0  0  0  0
 18 19  1  0  0  0  0
M  END
> <DATABASE_ID>
DB00405

> <DATABASE_NAME>
drugbank

> <SMILES>
CN(C)CC[C@@H](C1=CC=C(Br)C=C1)C1=CC=CC=N1

> <INCHI_IDENTIFIER>
InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1

> <INCHI_KEY>
ZDIGNSYAACHWNL-HNNXBMFYSA-N

> <FORMULA>
C16H19BrN2

> <MOLECULAR_WEIGHT>
319.239

> <EXACT_MASS>
318.073161265

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_ATOM_COUNT>
38

> <JCHEM_AVERAGE_NEUTRAL_MICROSPECIES_CHARGE>
0.9974034901515103

> <JCHEM_AVERAGE_POLARIZABILITY>
31.838223053045315

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
1

> <JCHEM_IUPAC>
[(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine

> <ALOGPS_LOGP>
3.63

> <JCHEM_LOGP>
3.749658864

> <ALOGPS_LOGS>
-4.40

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NEUTRAL_CHARGE>
1

> <JCHEM_NUMBER_OF_RINGS>
2

> <JCHEM_PHYSIOLOGICAL_CHARGE>
1

> <JCHEM_PKA_STRONGEST_BASIC>
9.478390040370506

> <JCHEM_POLAR_SURFACE_AREA>
16.130000000000003

> <JCHEM_REFRACTIVITY>
83.66830000000002

> <JCHEM_ROTATABLE_BOND_COUNT>
5

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.27e-02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
biotin

> <JCHEM_VEBER_RULE>
1

> <DRUGBANK_ID>
DB00405

> <SECONDARY_ACCESSION_NUMBERS>
APRD00770

> <DRUG_GROUPS>
approved

> <GENERIC_NAME>
Dexbrompheniramine

> <SYNONYMS>
(+)-brompheniraminum; (R)-3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine; (S)-(+)-brompheniramine; (S)-brompheniramine; 3-(4-bromophenyl)- N,N-dimethyl- 3-pyridin-2-yl-propan-1-amine; d-brompheniramine; Desbrofeniramina; Dexbromfeniramina; Dexbrompheniramin; Dexbromphéniramine; Dexbrompheniramine; Dexbrompheniraminum

> <PRODUCTS>
Accu Tuss DM; Acticon; Actidogesic; Actidogesic DF; Ala-hist Ir; Ala-hist PE; Alahist CF; Alahist DM; Alahist PE; Bio-cnex; Biogesic; Bionatuss DXP; BranTussin DM; Brompheniramine Maleate Pseudoephedrine HCl; Chlo Hist; Chlo Tuss; Conex; Coricidin 'd' Nasal and Sinus Congestion; Coricidin D Nasal and Sinus Congestion Tablets; Dallergy; Dexbrompheniramine Maleate and Phenylephrine Hydrochloride; Dexbrompheniramine-DM-Phenylephrine 2-15-7.5; Dexbrompherniramine Maleate and Pseudoephedrine Sulfate 6mg/120mg; Dologen; Dologen 325; Dologesic DF; Dologesic NF; Drixoral Cold & Sinus; Drixoral Day/night - Srt/tabs; Drixoral Syrup; Drixtab Tab; G-Con-X; G-Dologen; G-P-tuss Dxp; M-end Dmx; M-end Max D; Panatuss DXP; Panatuss Pediatric Drops DXP; PediaVent; Polytussin DM; Supress A; WesTussin DM NF

> <INTERNATIONAL_BRANDS>
Disophrol; Drixoral

> <SALTS>
Dexbrompheniramine maleate

$$$$