1189
  Mrv0541 02231215182D          

 10  9  0  0  1  0            999 V2000
    3.0791    0.9760    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -0.6740    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    1.9520    0.4529    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    2.7770   -0.9760    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    5.2224   -0.2615    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080    0.9760    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -0.2615    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791    0.1510    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -0.2615    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5080    0.1510    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  8  1  0  0  0  0
  2  9  1  0  0  0  0
  3  9  1  0  0  0  0
  4  9  1  0  0  0  0
  5 10  1  0  0  0  0
  6 10  1  0  0  0  0
  7  8  1  0  0  0  0
  7 10  1  0  0  0  0
  8  9  1  0  0  0  0
M  END
> <DATABASE_ID>
DB01189

> <DATABASE_NAME>
drugbank

> <SMILES>
FC(F)OC(F)C(F)(F)F

> <INCHI_IDENTIFIER>
InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H

> <INCHI_KEY>
DPYMFVXJLLWWEU-UHFFFAOYSA-N

> <FORMULA>
C3H2F6O

> <MOLECULAR_WEIGHT>
168.0378

> <EXACT_MASS>
168.000983916

> <JCHEM_ACCEPTOR_COUNT>
1

> <JCHEM_ATOM_COUNT>
12

> <JCHEM_AVERAGE_NEUTRAL_MICROSPECIES_CHARGE>
1.9844584349813426e-13

> <JCHEM_AVERAGE_POLARIZABILITY>
7.894929046218458

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane

> <ALOGPS_LOGP>
2.19

> <JCHEM_LOGP>
2.4025108229999996

> <ALOGPS_LOGS>
-1.68

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NEUTRAL_CHARGE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
18.870108514803245

> <JCHEM_PKA_STRONGEST_BASIC>
-4.810489555332021

> <JCHEM_POLAR_SURFACE_AREA>
9.23

> <JCHEM_REFRACTIVITY>
18.1205

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
3.54e+00 g/l

> <JCHEM_TRADITIONAL_IUPAC>
tetrahydrofolic acid

> <JCHEM_VEBER_RULE>
1

> <DRUGBANK_ID>
DB01189

> <SECONDARY_ACCESSION_NUMBERS>
APRD00907

> <DRUG_GROUPS>
approved

> <GENERIC_NAME>
Desflurane

> <SYNONYMS>
(±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether; 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane; Desflurane; Desflurano; Desfluranum; Difluoromethyl 1,2,2,2-tetrafluoroethyl ether

> <PRODUCTS>
Desflurane; Suprane

$$$$