Displaying drugs 2776 - 2800 of 3464 in total
Glucagon
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon, human …
Matched Description: … the movement of the gastrointestinal tract and to treat severe hypoglycemia. ... , stimulating glycogenolysis and the release of glucose. ... Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Medications that increase serum magnesium …
Matched Description: … the movement of the gastrointestinal tract and to treat severe hypoglycemia. ... , stimulating glycogenolysis and the release of glucose. ... Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Medications that increase serum magnesium …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
HUB-101
Investigational
Matched Synonyms: … Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene …
Ozanimod
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada...
Approved
Investigational
Matched Description: … pain, diarrhea, bloody stools, and vomiting. ... decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard ... once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ZEPOSİA 0,92 MG SERT KAPSÜL, 28 ADET …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ZEPOSİA 0,92 MG SERT KAPSÜL, 28 ADET …
Insulin-like growth factor II
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Human oligopeptide-24 ... Human insulin-like growth factor II ... Insulin-like growth factor II (human) …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... to circulate in the blood. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... to circulate in the blood. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Intercellular Signaling Peptides and Proteins …
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Synonyms: … Acidum mersalylicum …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Salts name: … Mersalyl sodium …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Salts name: … Mersalyl sodium …
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Description: … Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and ... Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. ... A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ERIVEDGE 150 MG SERT KAPSÜL ,28 KAPSÜL …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ERIVEDGE 150 MG SERT KAPSÜL ,28 KAPSÜL …
Idasanutlin
Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Investigational
Matched Synonyms: … BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2 …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Navtemadlin
Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acid …
Matched Iupac: … chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic acid …
Matched Description: … Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic acid …
Matched Description: … Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Fomepizole
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Salts name: … Fomepizole sulfate …
Matched Products: … Fomepizol SERB 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Salts name: … Fomepizole sulfate …
Matched Products: … Fomepizol SERB 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. ... symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … MIRTAZAPINA HUMAX® TABLETAS RECUBIERTAS ... MİTAZEN 15 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 12 AMPUL …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … MIRTAZAPINA HUMAX® TABLETAS RECUBIERTAS ... MİTAZEN 15 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 12 AMPUL …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Methionine C-11
Investigational
Matched Synonyms: … 2-Amino-4-[11C]methylsulfanyl-butanoic acid, l-[S methyl[11C]methionine …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
Experimental
Matched Name: … (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE …
Matched Iupac: … (5E)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …
Matched Iupac: … (5E)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …
RGX-111
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Cefamandole
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-carboxylic acid ... [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Sulfur Compounds …
CTS-1027
CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.
Experimental
Investigational
Matched Synonyms: … 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL )-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE ... 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
DSM-265
DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Matched Description: … DSM265 has been used in trials studying the prevention and treatment of Malaria. …
Thalidomide
A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Synonyms: … N-Phthalylglutamic acid imide …
Matched Description: … It has been reintroduced and used for a number of inflammatory disorders and cancers. ... Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of ... inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Carboxylic Acids …
Matched Products: … THALIDOMIDE CELGENE 50 MG SERT KAPSUL, 28 ADET …
Matched Description: … It has been reintroduced and used for a number of inflammatory disorders and cancers. ... Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of ... inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Carboxylic Acids …
Matched Products: … THALIDOMIDE CELGENE 50 MG SERT KAPSUL, 28 ADET …
SER-100
SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension).
Investigational
Matched Name: … SER-100 …
Matched Description: … SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension …
Matched Categories: … Amino Acids, Peptides, and Proteins …
SER-287
SER-287 comprises healthy microbiome-derived Gram positive bacterial spores.
Investigational
Matched Name: … SER-287 …
Matched Description: … SER-287 comprises healthy microbiome-derived Gram positive bacterial spores. …
Matched Description: … SER-287 comprises healthy microbiome-derived Gram positive bacterial spores. …
KAb201
Investigational
Matched Synonyms: … Anti-CEA sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) …
TALL-104
Investigational
Matched Synonyms: … Human major histocompatibility complex (MHC) non-restricted T-cell line 104 …
Displaying drugs 2776 - 2800 of 3464 in total