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Displaying drugs 2826 - 2850 of 3387 in total
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts name: … Desipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride
Investigational
Matched Synonyms: … 6-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine ... 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine …
Experimental
Matched Name: … 3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-imino-6-oxocyclohexa-1,4-dien-1-yl)propanoic acid
Experimental
Matched Name: … 5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid
Experimental
Matched Name: … 2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
Matched Iupac: … (3R)-2-{[1,1'-biphenyl]-4-sulfonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Experimental
Matched Name: … 3-[Isopropyl(4-Methylbenzoyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid
Matched Iupac: … 5-phenyl-3-[N-(propan-2-yl)4-methylbenzamido]thiophene-2-carboxylic acid
Experimental
Matched Name: … 2-KETO-6-PHOSPHATE-D-GLUCONIC ACID, ALPHA-FURANOSE FORM …
Matched Iupac: … (2R,3R,4S,5R)-2,3,4-trihydroxy-5-[(phosphonooxy)methyl]oxolane-2-carboxylic acid
Experimental
Matched Name: … 3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid
Matched Iupac: … 3-{[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]oxy}propanoic acid
Experimental
Matched Name: … 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID
Matched Iupac: … 2',4'-dichloro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Experimental
Matched Name: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Matched Iupac: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Experimental
Matched Name: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Matched Iupac: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Experimental
Matched Name: … 5-Amino-6-cyclohexyl-4-hydroxy-2-isobutyl-hexanoic acid
Matched Iupac: … (2R,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoic acid
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Description: … Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1 ... (I) and matrix metalloproteinase 2 (MMP-2) gene expression. ... Food and Drug Administration in March, 2000. …
Experimental
Investigational
Matched Synonyms: … L. reuteri …
Experimental
Matched Synonyms: … Aloe vera (l.) burm.f. leaf polysaccharides …
Matched Mixtures name: … Iodoquinol, Hydrocortisone Acetate, Aloe Polysaccharides ... Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% …
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … )-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)- ... 4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine …
Matched Description: … [A258393,L45633] Unlike other echinocandins such as [caspofungin] and [micafungin], rezafungin has long‐acting ... pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high ... Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol …
TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
Experimental
Matched Name: … 3-{[(1r)-1-Benzyl-2-Sulfanylethyl]Amino}-3-Oxopropanoic Acid
Matched Iupac: … 2-{[(2R)-1-phenyl-3-sulfanylpropan-2-yl]carbamoyl}acetic acid
Experimental
Matched Name: … 1(R)-1-Acetamido-2-(3-Carboxyphenyl)Ethyl Boronic Acid
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-acetamidoethyl]benzoic acid
Experimental
Matched Name: … 2-Amino-4-(4-Amino-Cyclohexa-2,5-Dienyl)-Butyric Acid
Matched Iupac: … (2S)-2-amino-4-(4-aminocyclohexa-2,5-dien-1-yl)butanoic acid
Experimental
Matched Name: … 2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid
Matched Iupac: … (3S,4S)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
Experimental
Matched Name: … PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) …
Experimental
Matched Name: … 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID
Matched Iupac: … (1R,6R)-2-(3-carboxypropanoyl)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
Displaying drugs 2826 - 2850 of 3387 in total