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Displaying drugs 351 - 375 of 14337 in total

Potassium acetate

Approved
Investigational
Matched Mixtures name: … Normosol-M and Dextrose ... Plasma-lyte 56 and Dextrose ... Normosol-M and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Griseofulvin

An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Approved
Investigational
Vet approved

Nisoldipine

Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Description: … of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Acetyldigitoxin

Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved

Tolazoline

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Categories: … Topical Products for Joint and Muscular Pain …

Sodium stibogluconate

Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). Widespread resistance has limited the utility of sodium stibogluconate,...
Approved
Investigational
Matched Description: … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration ... Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …

Nilvadipine

Nilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Approved
Investigational
Matched Categories: … Calcium-Regulating Hormones and Agents …

Carglumic acid

Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Description: … Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Technetium Tc-99m tetrofosmin

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Description: … by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and ... [A31592] Technetium Tc-99m tetrofosmin was developed by GE Healthcare and FDA approved on February 9, …
Matched Categories: … Indicators and Reagents …

Levamlodipine

Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive medication. Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. This medication was first marketed in Russia and India before being granted FDA approval. The names S-amlodipine and levamlodipine may be used interchangeably as both...
Approved
Investigational
Matched Description: … [L10833] This medication was first marketed in Russia and India before being granted FDA approval. ... [L1484] The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the ... [L10833] As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … intrinsic bone tissue quality and microarchitecture in osteoporosis by way of a number of cellular and ... presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and ... increased adverse cardiac effects profile along with increased risk of venous thromboembolism (VTE) and …
Matched Categories: … strontium ranelate and colecalciferol ... Drugs Affecting Bone Structure and Mineralization …

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … , arthrography, cholangiography, urography, and computed tomography [L1889]. ... Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... film, improving the visualization of important structures and organs during angiography, arteriography …

Metrizoic acid

Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with …

Tetrofosmin

Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved

Oftasceine

Oftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
Approved
Matched Description: … It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. …

Pentoxyverine

Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The...
Approved
Investigational
Withdrawn
Matched Description: … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. ... It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and ... carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and …
Matched Categories: … Cough and Cold Preparations …

Ethyl ferulate

Approved
Experimental

Tropisetron

Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Description: … radiotherapy-induced nausea and vomiting. ... competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and …

Bictegravir

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and …
Matched Categories: … emtricitabine, tenofovir alafenamide and bictegravir …

Hexobendine

Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany .
Approved
Matched Description: … has not been approved in the United States or the United Kingdom, but has been used widely in Austria and …

Ritiometan

Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.
Approved

Gamolenic acid

Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Description: … comprised of 18 carbon atoms with three double bonds [F27] that is most commonly found in human milk and ... omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6; 6,9,12-octadecatrienoic acid; and ... Gamolenic acid is found naturally in the fatty acid fractions of some plant seed oils [F27], [DB11358] and …

p-Phenylenediamine

Approved
Experimental
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Displaying drugs 351 - 375 of 14337 in total