Displaying drugs 3726 - 3750 of 4664 in total
Acetoacetyl-CoA
Experimental
Matched Synonyms: … 3-Acetoacetyl-CoA …
Matched Iupac: … ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
Matched Iupac: … ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
Z-Val-Ala-Asp fluoromethyl ketone
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Iupac: … acid ... (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …
Matched Description: … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … acid ... (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …
Matched Description: … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
TAK-075 Free base
Investigational
Matched Synonyms: … Pyrazolo(1,5-a)pyrimidine-3-carboxamide, n-(1-ethyl-1-(4-ethylphenyl)propyl)-4,5,6,7-tetrahydro-2,7,7 …
Matched Iupac: … 3-carboxamide ... (5R)-N-[3-(4-ethylphenyl)pentan-3-yl]-2,7,7-trimethyl-5-phenyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine- …
Matched Salts cas: … 667931-33-1 …
Matched Iupac: … 3-carboxamide ... (5R)-N-[3-(4-ethylphenyl)pentan-3-yl]-2,7,7-trimethyl-5-phenyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine- …
Matched Salts cas: … 667931-33-1 …
Acetyldigitoxin
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Digitoxin 3'''-acetate …
Matched Iupac: … (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-hydroxy-9a, ... -2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate ... 11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-hydroxy …
Matched Iupac: … (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-hydroxy-9a, ... -2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate ... 11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-hydroxy …
Allylestrenol
A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably not in the United States or Canada.
Experimental
Matched Synonyms: … 3-deketo-17α-allyl-19-nortestosterone …
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-methyl-1-(prop-2-en-1-yl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Description: … A synthetic steroid with progestational activity. ... It is widely marketed throughout Europe, including Russia and many other European countries, and is also ... available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (1R,3aS,3bR,9aR,9bS,11aS)-11a-methyl-1-(prop-2-en-1-yl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Description: … A synthetic steroid with progestational activity. ... It is widely marketed throughout Europe, including Russia and many other European countries, and is also ... available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Dexpropranolol
Experimental
Matched Synonyms: … (+)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol …
Matched Iupac: … (2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Iupac: … (2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Amitraz
Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with...
Experimental
Vet approved
Matched Synonyms: … 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-diene …
Matched Description: … Amitraz is a non-systemic acaricide and insecticide. ... Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. ... its driven inhibition of the synthesis of monoamine oxidases and prostaglandins. …
Matched Description: … Amitraz is a non-systemic acaricide and insecticide. ... Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. ... its driven inhibition of the synthesis of monoamine oxidases and prostaglandins. …
WIN 55212-2
WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of...
Experimental
Matched Synonyms: … (2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl …
Matched Iupac: … (11R)-2-methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12 …
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Matched Iupac: … (11R)-2-methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12 …
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Ilepcimide
Investigational
Matched Synonyms: … 1-((e)-3,4-(methylenedioxy)cinnamoyl)piperidine ... Piperidine, 1-(3-(1,3-benzodioxol-5-yl)-1-oxo-2-propenyl)-, (e)- …
Matched Iupac: … (2E)-3-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one …
Matched Iupac: … (2E)-3-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one …
Lansoprazole sulfone
Investigational
Matched Synonyms: … 1h-benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfonyl)- …
Matched Iupac: … 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfonyl}-1H-1,3-benzodiazole …
Matched Iupac: … 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfonyl}-1H-1,3-benzodiazole …
Rexlemestrocel-L
Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product. It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial infarction.
Investigational
Matched Synonyms: … Immunoselected stro-3+ allogenic mesenchymal precursor cells …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial …
ABSK-091
Investigational
Matched Synonyms: … Benzamide, n-(5-(2-(3,5-dimethoxyphenyl)ethyl)-1h-pyrazol-3-yl)-4-((3r,5s)-3,5-dimethyl-1-piperazinyl …
Matched Iupac: … N-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … N-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
PARPI F-18
PARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.
Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((4-fluoro-3-((4-(4-(fluoro-18f)benzoyl)-1-piperazinyl)carbonyl)phenyl)methyl) …
Matched Iupac: … 4-[(4-fluoro-3-{4-[4-(18F)fluorobenzoyl]piperazine-1-carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1- …
Matched Iupac: … 4-[(4-fluoro-3-{4-[4-(18F)fluorobenzoyl]piperazine-1-carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1- …
(9S,12S)-9-(1-methylethyl)-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid
Experimental
Matched Name: … (1-methylethyl)-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid …
Matched Iupac: … 7,10-dioxo-9-(propan-2-yl)-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid …
Matched Iupac: … 7,10-dioxo-9-(propan-2-yl)-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid …
(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid
Experimental
Matched Name: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
Matched Iupac: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
Matched Iupac: … (1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide ... hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3- …
Matched Iupac: … (10R,12S)-N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts cas: … 179463-17-3 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (10R,12S)-N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts cas: … 179463-17-3 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dazcapistat
Investigational
Matched Synonyms: … 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl- ... N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide ... N-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-5-oxazolecarboxamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …
Ropsacitinib
Investigational
Matched Synonyms: … Cyclobutaneacetonitrile, 3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4- yl)pyrazolo(1,5-a)pyrazin-4-yl)-1h-pyrazol ... Trans-3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrazolo(1,5-a)pyrazin-4-yl)- 1h-pyrazol-1-yl)-cyclobutaneacetonitrile …
Matched Iupac: … (1r,3r)-3-(cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl …
Matched Iupac: … (1r,3r)-3-(cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl …
Anisotropine methylbromide
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Synonyms: … 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide ... endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Fimepinostat
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Salts cas: … 1401998-36-4 …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Salts cas: … 1401998-36-4 …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
[(1S)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron
Experimental
Matched Name: … [(1S)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron …
(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE
Experimental
Matched Name: … (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE …
Matched Iupac: … (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one …
Matched Iupac: … (3Z)-6-(4-hydroxy-3-methoxyphenyl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one …
1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA
Experimental
Matched Name: … 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA …
Matched Iupac: … 1-(5-bromopyridin-2-yl)-3-[(1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea …
Matched Iupac: … 1-(5-bromopyridin-2-yl)-3-[(1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea …
Displaying drugs 3726 - 3750 of 4664 in total