Displaying drugs 26 - 50 of 332 in total
Tolazamide
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea ... 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Phenylephrine
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Synonyms: … l-(3-Hydroxyphenyl)-N-methylethanolamine ... R(-)-Phenylephrine …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 61-76-7 ... 1416-03-1 …
Matched Mixtures name: … CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML ... PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... DEFLU 300 MG/5 MG/2 MG TABLET, 20 ADET …
Matched Categories: … Amino Alcohols ... Adrenergic alpha-1 Receptor Agonists ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP1A2 Inducers (strength unknown) …
Matched Products: … 4 Way Fast Acting ... Green Guard Allergy 2 Relief ... 7 Select Nasal Decongestant PE …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Salts cas: … 61-76-7 ... 1416-03-1 …
Matched Mixtures name: … CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML ... PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... DEFLU 300 MG/5 MG/2 MG TABLET, 20 ADET …
Matched Categories: … Amino Alcohols ... Adrenergic alpha-1 Receptor Agonists ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP1A2 Inducers (strength unknown) …
Matched Products: … 4 Way Fast Acting ... Green Guard Allergy 2 Relief ... 7 Select Nasal Decongestant PE …
Chlorpropamide
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzenesulfonyl)-3-propylurea ... 1-(p-chlorophenylsulfonyl)-3-propylurea ... 1-propyl-3-(p-chlorobenzenesulfonyl)urea …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 3-(p-Tolyl-4-sulfonyl)-1-butylurea ... 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-p-Toluenesulfonyl-3-butylurea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Salts cas: … 473-41-6 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C18 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Salts cas: … 473-41-6 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C18 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Dalfampridine
Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Synonyms: … p-Aminopyridine ... 4-AP ... 4-Aminopyridine …
Matched Iupac: … 1,4-dihydropyridin-4-imine …
Matched Description: … Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2E1 Substrates ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 1,4-dihydropyridin-4-imine …
Matched Description: … Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2E1 Substrates ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Acetohexamide
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea ... 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide ... N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide ... 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Non Potassium Sparing Diuretics ... Sodium Potassium Chloride Symporter Inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Products: … TORASEMID 1A PHARMA 5 MG ... TORVENTA 5 MG TABLET, 20 ADET ... TORVENTA 5 MG TABLET, 30 ADET …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Non Potassium Sparing Diuretics ... Sodium Potassium Chloride Symporter Inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Products: … TORASEMID 1A PHARMA 5 MG ... TORVENTA 5 MG TABLET, 20 ADET ... TORVENTA 5 MG TABLET, 30 ADET …
Tetracycline
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl ... -1,11-dioxo-2-naphthacenecarboxamide …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene ... -2-carboxamide …
Matched Salts cas: … 64-75-5 ... 13930-32-0 …
Matched Mixtures name: … Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … Drugs for Acid Related Disorders ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Inhibitors …
Matched Products: … S-MEPROTETRA ... แอ็คนิซิน ที5 แค็ปซูล ... Achromycin Ont Oph 1% …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene ... -2-carboxamide …
Matched Salts cas: … 64-75-5 ... 13930-32-0 …
Matched Mixtures name: … Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … Drugs for Acid Related Disorders ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Inhibitors …
Matched Products: … S-MEPROTETRA ... แอ็คนิซิน ที5 แค็ปซูล ... Achromycin Ont Oph 1% …
Minoxidil
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide ... 2,4-Diamino-6-piperidinopyrimidine 3-oxide …
Matched Iupac: … 2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate …
Matched Salts cas: … 210357-39-4 …
Matched Mixtures name: … MINOXIDIL 7% / NIACINAMIDE 4% s ... Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Categories: … Potassium Channel Opener ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Yumhon 6% Minoxidil ... R-GER FORT 50 MG/ML SPREY, ÇÖZELTİ, 60 ML ... REGRO LOTION 3% …
Matched Iupac: … 2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate …
Matched Salts cas: … 210357-39-4 …
Matched Mixtures name: … MINOXIDIL 7% / NIACINAMIDE 4% s ... Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Categories: … Potassium Channel Opener ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Yumhon 6% Minoxidil ... R-GER FORT 50 MG/ML SPREY, ÇÖZELTİ, 60 ML ... REGRO LOTION 3% …
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Remular-S …
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Chlorhexidine
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched International brands: … Prevacare R …
Matched Synonyms: … 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) ... N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Salts cas: … 56-95-1 ... 3697-42-5 ... 18472-51-0 …
Matched Mixtures name: … ANZİBEL 5 MG/4 MG/3 MG EKİNEZYALI PASTİL, 20 ADET ... ANZİBEL 5 MG/4 MG/3 MG MEYANBALLI PASTİL, 20 ADET ... ANZİBEL 5 MG/4 MG/3 MG ZENCEFİLLİ PASTİL, 20 ADET …
Matched Products: … Zheng s acteriostatic gel ... 3M AVAGARD LAVDO DE MANOS ANTISEPTICO CON GLUCONATO DE CLORHEXIDINA AL 4% P/P FRASCO ... (LAVADO ANTISEPTICO DE MANOS Y CUERPO CON GLUCONATO DE CLORHEXIDINA AL 2% P/P FRASCO …
Matched Synonyms: … 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) ... N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Salts cas: … 56-95-1 ... 3697-42-5 ... 18472-51-0 …
Matched Mixtures name: … ANZİBEL 5 MG/4 MG/3 MG EKİNEZYALI PASTİL, 20 ADET ... ANZİBEL 5 MG/4 MG/3 MG MEYANBALLI PASTİL, 20 ADET ... ANZİBEL 5 MG/4 MG/3 MG ZENCEFİLLİ PASTİL, 20 ADET …
Matched Products: … Zheng s acteriostatic gel ... 3M AVAGARD LAVDO DE MANOS ANTISEPTICO CON GLUCONATO DE CLORHEXIDINA AL 4% P/P FRASCO ... (LAVADO ANTISEPTICO DE MANOS Y CUERPO CON GLUCONATO DE CLORHEXIDINA AL 2% P/P FRASCO …
Pyridoxine
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 5-hydroxy-6-methyl-3,4-pyridinedimethanol ... 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine ... 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine …
Matched Iupac: … 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Description: … and aminolevulinic acid. ... Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally ... B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s …
Matched Salts cas: … 58-56-0 …
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... P-NATAL® ... Formula R Tab …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Pyridoxine-S Tab 50mg ... B 6 VIGEN 250 MG AMPUL, 3 ADET ... LIBAVIT-B 6 FORT AMPUL, 3 ADET …
Matched Iupac: … 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Description: … and aminolevulinic acid. ... Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally ... B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s …
Matched Salts cas: … 58-56-0 …
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... P-NATAL® ... Formula R Tab …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Pyridoxine-S Tab 50mg ... B 6 VIGEN 250 MG AMPUL, 3 ADET ... LIBAVIT-B 6 FORT AMPUL, 3 ADET …
Dofetilide
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Synonyms: … beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide …
Matched Iupac: … N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide …
Matched Categories: … Potassium Channel Blockers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide …
Matched Categories: … Potassium Channel Blockers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Synonyms: … 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol ... 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol …
Matched Iupac: … 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol …
Matched Salts cas: … 6078-56-4 …
Matched Categories: … Amino Alcohols ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... Isoproterenol HCl Inj 1:5000 …
Matched Iupac: … 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol …
Matched Salts cas: … 6078-56-4 …
Matched Categories: … Amino Alcohols ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... Isoproterenol HCl Inj 1:5000 …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl ... )-pyridyl-2-methane (BHPM). …
Matched Mixtures name: … BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET ... Gentlax S …
Matched Products: … P Lax Dr ... ERPLUS(R) GRAGEAS ... BET-R-PREP Bisacodyl …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl ... )-pyridyl-2-methane (BHPM). …
Matched Mixtures name: … BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET ... Gentlax S …
Matched Products: … P Lax Dr ... ERPLUS(R) GRAGEAS ... BET-R-PREP Bisacodyl …
Pirenzepine
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also...
Approved
Matched Synonyms: … 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one …
Matched Iupac: … 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Salts cas: … 29868-97-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Acid Related Disorders …
Matched Iupac: … 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Salts cas: … 29868-97-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Acid Related Disorders …
Drospirenone
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Synonyms: … 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone …
Matched Iupac: … .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione ... (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} …
Matched Mixtures name: … Angeliq 1 mg/2 mg Filmtabletten ... ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET ... Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates (strength unknown) …
Matched Products: … Lyzbet 4 mg Filmtabletten ... GYNETS® 4 MG TABLETAS RECUBIERTAS ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …
Matched Iupac: … .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione ... (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} …
Matched Mixtures name: … Angeliq 1 mg/2 mg Filmtabletten ... ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET ... Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates (strength unknown) …
Matched Products: … Lyzbet 4 mg Filmtabletten ... GYNETS® 4 MG TABLETAS RECUBIERTAS ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … 5-azaorotic acid ... Oxonic Acid ... Allantoxanic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5- …
Matched Salts cas: … 2207-75-2 …
Matched Salts name: … Oteracil potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, 5- …
Matched Salts cas: … 2207-75-2 …
Matched Salts name: … Oteracil potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Glimepiride
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- ... 2,5-dihydro-1H-pyrrole-1-carboxamide …
Matched Description: … stimulating the secretion of insulin granules from pancreatic islet beta cells by blocking ATP-sensitive potassium ... Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … GLIMEPIRIDE SANDOZ(R) (2 MG) ... Amaryl 6 mg Tabletten ... AMARYL 6 MG TABLET, 30 ADET …
Matched Description: … stimulating the secretion of insulin granules from pancreatic islet beta cells by blocking ATP-sensitive potassium ... Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes …
Matched Mixtures name: … GLUCOVEL 1 ... VELACOM PLUS 1/250 ... AMARYL®M 1 MG/ 500 MG …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … GLIMEPIRIDE SANDOZ(R) (2 MG) ... Amaryl 6 mg Tabletten ... AMARYL 6 MG TABLET, 30 ADET …
Repaglinide
Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood...
Approved
Investigational
Matched Iupac: … 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid …
Matched Mixtures name: … REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/1000 MG EFERVESAN TABLET, 90 ADET …
Matched Categories: … Carboxylic Acids ... Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … Repaglinid STADA 4 mg Tabletten ... Repaglinid Sandoz 4 mg - Tabletten ... NOVONORM TABLET 1 mg …
Matched Mixtures name: … REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/1000 MG EFERVESAN TABLET, 90 ADET …
Matched Categories: … Carboxylic Acids ... Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … Repaglinid STADA 4 mg Tabletten ... Repaglinid Sandoz 4 mg - Tabletten ... NOVONORM TABLET 1 mg …
Sodium zirconium cyclosilicate
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … levels in the blood was 2.2 hours, with 92% of patients achieving normal potassium levels within 48 ... sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium ... showed that the onset of action was approximately 1.0 hour and the median time to achieving normal potassium …
Matched Categories: … Gastric Acid Lowering Agents ... Potassium Binder ... Potassium-removing Agents …
Matched Products: … SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET ... SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET …
Matched Categories: … Gastric Acid Lowering Agents ... Potassium Binder ... Potassium-removing Agents …
Matched Products: … SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET ... SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET …
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Synonyms: … 6-Dimethylamino-4,4-diphenyl-3-heptanone …
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Salts cas: … 1095-90-5 …
Matched Categories: … P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … Methasan 2 mg/ml-Sirup ... Methasan 5 mg-Tabletten …
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Salts cas: … 1095-90-5 …
Matched Categories: … P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … Methasan 2 mg/ml-Sirup ... Methasan 5 mg-Tabletten …
Cholecalciferol
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … Activated 7-dehydrocholesterol ... Vitamin D-3 ... (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene ... }-4-methylidenecyclohexan-1-ol …
Matched Description: … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there ... Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... P-NATAL® ... Pregvit Folic 5 …
Matched Categories: … ibandronic acid and colecalciferol ... risedronic acid and colecalciferol ... alendronic acid and colecalciferol ... Cytochrome P-450 Substrates ... zoledronic acid, calcium and colecalciferol, sequential …
Matched Products: … YYUX Organic Liquid Vitamin D3 Drops For Baby 0-3 years 400 IU ... YUMUŞAK KAPSÜL , 6 KAPSÜL ... DEVİT-3 300.000 I.U. /ML I.M. ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene ... }-4-methylidenecyclohexan-1-ol …
Matched Description: … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there ... Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin …
Matched Mixtures name: … Acti-cal/mag 2:1 + Zinc and D Caplet ... P-NATAL® ... Pregvit Folic 5 …
Matched Categories: … ibandronic acid and colecalciferol ... risedronic acid and colecalciferol ... alendronic acid and colecalciferol ... Cytochrome P-450 Substrates ... zoledronic acid, calcium and colecalciferol, sequential …
Matched Products: … YYUX Organic Liquid Vitamin D3 Drops For Baby 0-3 years 400 IU ... YUMUŞAK KAPSÜL , 6 KAPSÜL ... DEVİT-3 300.000 I.U. /ML I.M. ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 ML ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride …
Matched Categories: … P-glycoprotein inhibitors …
Matched Products: … MACRO P ... BET-R-Prep ... PEGDİN 227,1 G ORAL ÇÖZELTİ İÇİN TOZ, 1 POŞET …
Matched Categories: … P-glycoprotein inhibitors …
Matched Products: … MACRO P ... BET-R-Prep ... PEGDİN 227,1 G ORAL ÇÖZELTİ İÇİN TOZ, 1 POŞET …
Hydrocortisone
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Synonyms: … 4-pregnen-11β,17α,21-triol-3,20-dione ... (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione ... 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, ... 5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Description: … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] …
Matched Mixtures name: … HERPAZON % 5 + % 1 KREM, 5 GRAM ... HYDROCORTISONE 1% ET UREA 5% CREAM ... Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inducers ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … SANATISON MONO 1/3% ... K & P HYDROCORT 1 % CREME ... S-Oint HYDROCORTISONE 1% …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, ... 5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Description: … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] …
Matched Mixtures name: … HERPAZON % 5 + % 1 KREM, 5 GRAM ... HYDROCORTISONE 1% ET UREA 5% CREAM ... Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inducers ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … SANATISON MONO 1/3% ... K & P HYDROCORT 1 % CREME ... S-Oint HYDROCORTISONE 1% …
Displaying drugs 26 - 50 of 332 in total