Displaying drugs 26 - 41 of 41 in total
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) ... Thrombin alfa …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … , and as a result, leads to the conversion of fibrinogen to fibrin, the fibrous protein that creates ... signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Matched Name: … Antihemophilic factor human …
Matched Description: … , and as a result, leads to the conversion of fibrinogen to fibrin, the fibrous protein that creates ... signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Coagulation factor VII human
Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Approved
Investigational
Matched Synonyms: … Factor VII human ... Coagulation factor VII (human) ... Human coagulation factor VII …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Matched Name: … Coagulation factor VII human …
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Simoctocog alfa
Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Description: … patterns found in non-human cell lines led to decreased immunogenicity and longer half-life [A31525]. ... The harvested product is concentrated and purified by a series of chromatography steps. ... + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Crotalus atrox antivenin
Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 .
Crotalus atrox antivenin...
Approved
Experimental
Matched Description: … Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide ... isolating the antivenin of interest through fractionation and chromatography techniques. ... The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F113]. …
Dabigatran etexilate
Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Matched Description: … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Betrixaban
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Edoxaban
Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Description: … INR testing, and numerous drug-drug and drug-food interactions. ... atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism ... Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Andexanet alfa
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Description: … deters the andexanet alfa from converting prothrombin to thrombin [A35558]. ... Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. ... Andexanet alfa retains the structural similarity to that of endogenous human factor Xa, but exists in …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and …
Matched Mixtures name: … Co-q10 and Vitamin E ... Multi-Vitamin Fluoride and Iron Drops ... Revit Multi-vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Matched Mixtures name: … Co-q10 and Vitamin E ... Multi-Vitamin Fluoride and Iron Drops ... Revit Multi-vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Nafamostat
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome …
TP-508
TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Investigational
Matched Description: … TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified …
SR-123781A
SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Investigational
Matched Description: … It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary ... SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. …
Matched Categories: … Heparin and similars …
Matched Categories: … Heparin and similars …
Displaying drugs 26 - 41 of 41 in total