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Displaying drugs 576 - 600 of 706 in total

AZD2066

Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …

Nedometinib

Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …

Telacebec

Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …
Matched Salts name: … Sertraline hydrochloride …
Matched Products: … Sertraline Hydrochloride ... Sertraline hydrochloride ... SERTRAline Hydrochloride …

Lincomycin

Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use.[A190657, A190621] Lincomycin was approved...
Approved
Vet approved
Matched Description: … has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and …
Matched Salts name: … Lincomycin hydrochloride ... Lincomycin hydrochloride monohydrate …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Products: … Lincomycin Hydrochloride ... Lincomycin hydrochloride …

Flavoxate

A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … Its therapeutic usefulness and its mechanism of action are not clear. ... A drug that has been used in various urinary syndromes and as an antispasmodic. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Flavoxate Hydrochloride …

Dapiprazole

Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Salts name: … Dapiprazole hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Salts name: … Thioridazine hydrochloride …
Matched Products: … Thioridazine Hydrochloride …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …

Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been …
Matched Mixtures name: … Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide …
Matched Salts name: … Clindamycin hydrochloride ... Clindamycin palmitate hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … Clindamycin Hydrochloride ... Clindamycin hydrochloride ... Cleocin Hydrochloride …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Salts name: … Granisetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Granisetron Hydrochloride ... Granisetron hydrochloride ... GRANISETRON HYDROCHLORIDE …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Hydrochloride ... Remifentanil Hydrochloride for Injection …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Nortriptyline Hydrochloride …

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride …

Setanaxib

Investigational
Matched Synonyms: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-C]pyridine-3,6(2H,5H)-dione …
Matched Iupac: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H,2H,3H,5H,6H-pyrazolo[4,3-c]pyridine-3,6-dione …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … Bruce Roth and approved by the FDA in 1996. ... lipid levels, and ultimately reduce the risk of cardiovascular disease. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium …
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... ATORVASTATIN CALCIUM …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … Pyridine-4-carboxylic acid hydrazide …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Categories: … isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... ethambutol and isoniazid ... rifampicin and isoniazid ... streptomycin and isoniazid ... thioacetazone and isoniazid …

Amlexanox

Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism …

TP-3654

Investigational
Matched Synonyms: … 2-(trans-4-((3-(3-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin6-yl)amino)cyclohexyl)propan-2-ol hydrochloride …
Matched Salts name: … TP-3654 hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Salts name: … Mitoxantrone hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …

Thieno[2,3-B]Pyridine-2-Carboxamidine

Experimental
Matched Name: … Thieno[2,3-B]Pyridine-2-Carboxamidine …

3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid

Experimental
Matched Name: … 3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid …
Matched Iupac: … 3-(phosphonomethyl)pyridine-2-carboxylic acid …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride …

Tramadol

Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … of and response to pain. ... such as [duloxetine] and [venlafaxine]. ... ) that is structurally related to [codeine] and [morphine]. …
Matched Mixtures name: … Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen ... Tramadol Hydrochloride and Acetaminophen …
Matched Salts name: … Tramadol hydrochloride …
Matched Categories: … tramadol and celecoxib ... tramadol and paracetamol ... tramadol and dexketoprofen …
Matched Products: … Tramadol Hydrochloride ... Tramadol Hydrchloride ... Tramadol hydrochloride …
Displaying drugs 576 - 600 of 706 in total