Displaying drugs 51 - 75 of 280 in total
Reslizumab
Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Papain
Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, Carica papaya and Vasconcellea cundinamarcensis. The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain...
Approved
Matched Description: … Papain is also used as an ingredient in various enzymatic debriding preparations. …
Matched Mixtures name: … Neo Life Beta Gest Tab …
Matched Mixtures name: … Neo Life Beta Gest Tab …
Saxagliptin
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Sincalide
Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as CCK-8. Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating protein and fat digestion...
Approved
Matched Description: … It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as _CCK- ... ), sincalide is used to stimulate the duodenum, pancreas, and small bowel for cholesterol analysis, enzymatic …
Viltolarsen
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Niraparib
Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. Niraparib is selective towards PARP-1 and PARP-2. First approved by the FDA on March 27, 2017, niraparib is used to treat epithelial ovarian, fallopian tube, or...
Approved
Investigational
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Soybean oil
Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Ivosidenib
Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Description: … [A248750] Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation …
Sofpironium
Sofpironium is a "soft" anticholinergic analog of glycopyrronium that has been modified with a readily hydrolyzable ester moiety. Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug design, in which a molecule contains a metabolically sensitive moiety that promotes rapid metabolism to inactive...
Approved
Investigational
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Migalastat
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Description: … A (alpha-Gal A). ... under Amicus Therapeutics' brand name Galafold) is subsequently an oral pharmacological chaperone of alpha-Gal ... progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …
Moxidectin
Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Iupac: … (1'R,2R,4E,4'S,5S,6S,8'R,10'E,13'R,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-4-(methoxyimino)-5,11' …
Von Willebrand factor human
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Mixtures name: … OPTIVATE(R) …
Dutasteride
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Latanoprostene bunod
Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure.
As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle...
Approved
Investigational
Matched Description: … subsequently lies in the proposed dual mechanism of action that stems from both its prostaglandin F2-alpha ... In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. ... analog latanoprost acid metabolite and its ability to donate NO for proposed tissue/cell relaxation …
Octocrylene
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin...
Approved
Investigational
Matched Description: … Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing …
Matched Mixtures name: … Pro-Collagen Marine Broad Spectrum SPF 30 ... HEB SPF 50 Hydrate 50 Sunscreen with Hyaluronic Acid and Collagen Continuous Sunscreen ... bu SPF 50 Broad Spectrum on Alcohol-Free Performance Sunscreen - Fragrance Free …
Matched Mixtures name: … Pro-Collagen Marine Broad Spectrum SPF 30 ... HEB SPF 50 Hydrate 50 Sunscreen with Hyaluronic Acid and Collagen Continuous Sunscreen ... bu SPF 50 Broad Spectrum on Alcohol-Free Performance Sunscreen - Fragrance Free …
Pork collagen
Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic, full-thickness cartilage defects of the knee with or without bone involvement in adults. It serves as an alternative repair treatment for patients...
Approved
Investigational
Matched Synonyms: … Collagen Porcine ... Collagen, Porcine …
Matched Name: … Pork collagen …
Matched Description: … Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as …
Matched Mixtures name: … Le-Blen Nano Collagen Peptide Serum …
Matched Name: … Pork collagen …
Matched Description: … Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as …
Matched Mixtures name: … Le-Blen Nano Collagen Peptide Serum …
Lipoic acid
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … R-alpha-lipoic acid ... (+)-alpha-Lipoic acid ... Alpha lipoic acid …
Matched Name: … Lipoic acid …
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …
Matched Mixtures name: … NutraVita MARINE COLLAGEN + ALA Capsule ... Essential Pro ALPHA-G Q10 Capsule …
Matched Categories: … thioctic acid …
Matched Products: … ALPHA LIPOIC ACID CAPSULE ... LIPO-X (ALPHA LIPOIC ACID 50MG) ... GNC-ALPHA LIPOIC ACID 100MG …
Matched Name: … Lipoic acid …
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …
Matched Mixtures name: … NutraVita MARINE COLLAGEN + ALA Capsule ... Essential Pro ALPHA-G Q10 Capsule …
Matched Categories: … thioctic acid …
Matched Products: … ALPHA LIPOIC ACID CAPSULE ... LIPO-X (ALPHA LIPOIC ACID 50MG) ... GNC-ALPHA LIPOIC ACID 100MG …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … Alendronic acid ... 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid …
Matched Name: … Alendronic acid …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Description: … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … alendronic acid ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ALENDRON BETA 1XWOECH70MG ... ALDRONA 70 (Alendronic acid Tablets 70 mg) …
Matched Name: … Alendronic acid …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Description: … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … alendronic acid ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ALENDRON BETA 1XWOECH70MG ... ALDRONA 70 (Alendronic acid Tablets 70 mg) …
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... of lab-grown skin cells, keratinocytes and dermal fibroblasts, which are grown together on a murine collagen …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... of lab-grown skin cells, keratinocytes and dermal fibroblasts, which are grown together on a murine collagen …
Threonine
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Synonyms: … L-alpha-amino-beta-hydroxybutyric acid ... 2-Amino-3-hydroxybutyric acid ... L-2-Amino-3-hydroxybutyric acid …
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid …
Matched Description: … An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Travasol Amino Acid Inj 8.5% ... Travasol Amino Acid Inj 5.5% ... Amino Acid InJ.W.elecw.25%dex …
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid …
Matched Description: … An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Travasol Amino Acid Inj 8.5% ... Travasol Amino Acid Inj 5.5% ... Amino Acid InJ.W.elecw.25%dex …
Vitamin E
In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … alpha-tocopherol ... (R,R,R)-α-tocopherol ... (2R,4'R,8'R)-α-tocopherol …
Matched Description: … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol …
Matched Mixtures name: … Marine Omega Softgels ... Total Image Collagen Plus ... Ferulic Acid CE Skin Serum …
Matched Products: … VITAMINA E 400 IU DL-ALPHA …
Matched Description: … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol …
Matched Mixtures name: … Marine Omega Softgels ... Total Image Collagen Plus ... Ferulic Acid CE Skin Serum …
Matched Products: … VITAMINA E 400 IU DL-ALPHA …
Glycerin
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Synonyms: … Glycerin ... Glycerin,anhydrous ... Glycerin, anhydrous …
Matched Name: … Glycerin …
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Aqua Collagen Solu Tion Marine Hydroge L Eye Crea M Mask ... Curel Alpha Hydroxy Dry Skin Lotion ... 2% Salicylic Acid FACIAL CLEANSER …
Matched Products: … Aqua Collagen Hyaluronic Acid Hydro Mask ... White Flower Pig Collagen Foi L Mask Sheet ... Aqua Collagen Marine Hydro Lip …
Matched Name: … Glycerin …
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Aqua Collagen Solu Tion Marine Hydroge L Eye Crea M Mask ... Curel Alpha Hydroxy Dry Skin Lotion ... 2% Salicylic Acid FACIAL CLEANSER …
Matched Products: … Aqua Collagen Hyaluronic Acid Hydro Mask ... White Flower Pig Collagen Foi L Mask Sheet ... Aqua Collagen Marine Hydro Lip …
Displaying drugs 51 - 75 of 280 in total