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Displaying drugs 76 - 100 of 332 in total
Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Approved
Investigational
Matched Iupac: … 3-cyclohexyl-1-{4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonyl …
Matched Description: … Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
Approved
Investigational
Matched Iupac: … (82Rb)rubidium(1+) ion …
Matched Salts cas: … 132486-03-4
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Iupac: … 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol …
Matched Description: … [A183737] Salmeterol was granted FDA approval on 4 February 1994.[L11542] ... Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2
Matched Salts cas: … 94749-08-3
Matched Mixtures name: … HOVID CLEFAN-S POWDER FOR INHALATION 50/250MCG …
Matched Categories: … Amino Alcohols ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates …
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … -2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid ... -bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29 ... (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21 ... -decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl …
Matched Description: … tryptophan covalently bonded to decanoic acid. ... and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... [A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard …
Matched Categories: … P-glycoprotein substrates ... Amino Acids, Peptides, and Proteins …
Matched Products: … XAPTO 350 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Approved
Matched Iupac: … 1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium …
Matched Salts cas: … 52-62-0
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Iupac: … 1-methyl-2-{[4-(methylsulfanyl)phenoxy]methyl}-5-nitro-1H-imidazole …
Matched Description: … sleeping sickness), caused by _T. brucei gambiense_ and _T. brucei rhodesiense_, remains a moderate risk (>1/ …
Matched Categories: … MATE 2 Inhibitors ... MATE 2-K Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Organic Anion Transporter 1 Inhibitors …
Approved
Illicit
Matched Synonyms: … 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate …
Matched Iupac: … (1S,3aS,3bR,5aS,8R,9aS,9bS,11aS)-8,9a,11a-trimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug...
Approved
Investigational
Vet approved
Withdrawn
Matched Iupac: … 2,2-dichloro-1,1-difluoro-1-methoxyethane …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … Penthrop 99,9%, 3 ml Flüssigkeit zur Herstellung eines Dampfs zur Inhalation …
A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
Approved
Investigational
Withdrawn
Matched Iupac: … 1-carbamimidamido-N-(2-phenylethyl)methanimidamide …
Matched Salts cas: … 834-28-6
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH ... ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers …
Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Iupac: … [8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one ... (1R,2S,8S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1,8-difluoro-14,17-dihydroxy-2,13,15-trimethyltetracyclo …
Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … {2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH ... ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid
Matched Description: … [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] …
Matched Categories: … P-glycoprotein inducers ... Cytochrome P-450 CYP3A Inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A4 Inducers …
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … (2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
Matched Salts cas: … 1639-60-7 ... 26570-10-5
Matched Categories: … Carboxylic Acids ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A Substrates …
Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle...
Approved
Investigational
Matched Iupac: … 4-(nitrooxy)butyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept ... -5-enoate …
Matched Description: … As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution ... In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. ... proposed dual mechanism of action that stems from both its prostaglandin F2-alpha analog latanoprost acid
Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins …
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 ... ]heptane-2-carboxylic acid ... 6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 ... ]heptane-2-carboxylic acid
Matched Salts cas: … 61336-70-7
Matched Mixtures name: … AMOXICILLIN R C875MG/125MG ... AMOXICILLIN R C875MG/125MG ... HELIPAK 500 + 30 + 1000mg TEDAVİ PAKETİ, 7 TABLET …
Matched Salts name: … Amoxicillin Trihydrate
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Drugs for Acid Related Disorders ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …
Matched Products: … AMOXICILLIN TRIHYDRATE ... MOXYLIN 3 G POLVO PARA SUSPENSION ... BRENOXIL-S
Potassium gluconate is a salt of DB01345 and is classified as a food additive by the FDA . It is also used as a potassium supplement . Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining...
Approved
Matched Synonyms: … Potassium gluconate ... potassium D-gluconate …
Matched Name: … Potassium gluconate …
Matched Iupac: … potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate …
Matched Description: … It is also used as a potassium supplement [L2657]. Potassium is an essential nutrient. ... Potassium gluconate is believed to be more palatable and non-acidifying than potassium chloride (KCl) ... In dietary supplements, potassium is often present as potassium chloride, but many other forms—including …
Matched Mixtures name: … Potassium W Folic Acid Tab ... Iode-potassium ... Potassium Plus Vit B Complex …
Matched Categories: … Potassium Salt ... potassium gluconate …
Matched Products: … Potassium Tab 8.3mg ... Potassium Rougier ... Potassium Tab 99mg …
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid ... 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid
Matched Salts cas: … 5321-32-4
Matched Salts name: … Hetacillin potassium
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Synonyms: … hydroxyde de potassium ... Potassium hydroxide …
Matched Name: … Potassium hydroxide …
Matched Iupac: … potassium hydroxide …
Matched Description: … Potassium hydroxide is also a precursor to other potassium compounds. ... Liquid drain cleaners contain 25 to 36% of potassium hydroxide [L1946]. ... Potassium hydroxide, also known as _lye_ is an inorganic compound with the chemical formula _KOH_. …
Matched Mixtures name: … Aminomix 2 Novum - Infusionslösung ... Aminomix 1 Novum - Infusionslösung ... Kalium-L-malat "Fresenius" 1 molar - Infusionszusatz - Ampullen …
Matched Categories: … Potassium Salt …
Matched Products: … MIRACLE WATER 3 in 1 ... Potassium Hydroxide …
Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Synonyms: … Potassium nitrate …
Matched Name: … Potassium nitrate …
Matched Iupac: … potassium nitrate …
Matched Description: … Potassium nitrate is an inorganic salt with a chemical formula of KNO3. ... In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. ... Potassium nitrate is a common active ingredient in toothpaste, exerting an anti-sensitivity action. …
Matched Mixtures name: … DOCTRUST ONE S Tooth ... 4 Pack ... 4 Pack …
Matched Categories: … Potassium Salt …
Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. It presents a large capacity to absorb moisture.
Approved
Matched Synonyms: … Carbonic acid, dipotassium salt ... Potassium carbonate ... Potassium carbonate, anhydrous …
Matched Name: … Potassium carbonate …
Matched Description: … It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. ... Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly …
Matched Categories: … Carbonic Acid ... Potassium Salt …
Matched Products: … Food-S ... Face-body-S ... Cleaning-S
A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Synonyms: … Bismuth subcitrate potassium anhydrous …
Matched Name: … Bismuth subcitrate potassium
Matched Iupac: … bismuth(3+) pentapotassium bis(2-oxidopropane-1,2,3-tricarboxylate) …
Matched Mixtures name: … KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 ML ... Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride …
Matched Salts name: … Bismuth subcitrate potassium monohydrate …
Matched Categories: … Drugs for Acid Related Disorders …
Matched Products: … KREVAL7.5 MG/5 ML ŞURUP, 200 ML ... BUTAMCOD FORT 15 MG/5 ML ŞURUP, 200 ML ... KREVAL FORTE 15 MG/5 ML SURUP 200 ML …
Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O). Potassium alum is formed by large, transparent crystals that...
Approved
Matched Synonyms: … Alum, potassium ... Burnt potassium alum ... Aluminum potassium alum …
Matched Name: … Potassium alum …
Matched Iupac: … aluminium(3+) potassium disulfate …
Matched Description: … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that ... is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O). ... Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. …
Matched Mixtures name: … Gingicord W/epineph and Alum Size 2 ... Gingicord W Epineph and Alum Size No 1 ... Gingicord W Epineph and Alum Size No 3
Matched Salts name: … Potassium alum dodecahydrate …
Matched Categories: … Potassium Salt …
Matched Products: … Sulpak R 26 ... Sulpak R 25 ... Sulpak R 24 …
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … potassium(1+) ... potassium(1+) ion ... Potassium ion …
Matched Name: … Potassium cation …
Matched Iupac: … potassium(1+) ion …
Matched Description: … The balance between potassium and sodium is maintained by ion pumps in the cell membrane. ... Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside ... Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of …
Matched Categories: … Potassium Salt …
Displaying drugs 76 - 100 of 332 in total