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Displaying drugs 76 - 100 of 103 in total

Triamterene

Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side. Since it acts on...
Approved
Matched Description: … is approved for use with other diuretics to enhance diuretic and potassium-sparing effects. ... It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion ... Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management …
Matched Mixtures name: … Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide …
Matched Categories: … Potassium-Sparing Diuretics …

Methazolamide

A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Description: … A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Kerasal foot and toe ... Up and Up Athletes Foot ... Protective Nail and skin …

Desvenlafaxine

Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched Description: … a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …

Diclofenac

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac potassium …
Matched Categories: … diclofenac and antiinfectives ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM …

Zinc sulfate

Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Description: … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab ... Prenatal Vitamin and Mineral Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Skin and Mucous Membrane Agents ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Diazoxide

Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels ... and electrolyte disturbances. ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular …
Matched Categories: … Potassium Channel Opener …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts ... Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and …
Matched Categories: … Non Potassium Sparing Diuretics ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … and the nervous and digestive systems. ... It is essential for normal growth and development and helps to maintain proper functioning of the heart ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. …
Matched Mixtures name: … Chela Potassium Plus ... Potassium Plus Vit B Complex ... Somarexin and C 1000 …
Matched Salts name: … Thiamine chloride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …

Clofazimine

Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin...
Approved
Investigational
Matched Description: … , in its clinical use, results in long-lasting discoloration of the skin and bodily fluids. ... It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that ... considered an ineffective treatment in comparison to classic tuberculosis treatments such as [rifampicin] and …
Matched Categories: … dapsone, rifampicin and clofazimine …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin …
Matched Salts name: … Glucosamine sulfate potassium chloride ... Glucosamine sulfate sodium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Stiripentol

Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Description: … [A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the ... [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated …

Calcium magnesium potassium carbonate chloride hydroxide

Experimental
Matched Name: … Calcium magnesium potassium carbonate chloride hydroxide …
Matched Iupac: … calcium magnesium(2+) dipotassium(2+) chloride trihydroxide carbonate …

Tetraethylammonium

Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Description: … voltage- activated potassium channels, and nicotinic acetylcholine receptors. ... Structurally, tetraethylammonium is positively charged due to its central quaternary ammonium. ... As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride …
Matched Salts name: … Tetraethylammonium chloride ... Tetraethylammonium iodide …
Matched Categories: … Potassium Channel Blockers ... Quaternary Ammonium Compounds …

Tridihexethyl

Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Tridihexethyl is an antimuscarinic, anticholinergic drug. Tridihexethyl is no longer available in the US market.
Withdrawn
Matched Description: … Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical ... studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. …
Matched Salts name: … Tridihexethyl chloride …
Matched Categories: … Alimentary Tract and Metabolism ... Ammonium Compounds ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …

Epitizide

Epitizide is an agent, commonly found in combination triamterene, used to produce diuresis.
Experimental
Matched Categories: … epitizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Sodium Chloride Symporter Inhibitors …

Methyclothiazide

A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Categories: … methyclothiazide and potassium ... Sodium Chloride Symporter Inhibitors …

Tripamide

Experimental
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …

Bamocaftor

Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Description: … Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and …
Matched Salts name: … Bamocaftor potassium …
Matched Categories: … Chloride Channel Agonists …

Azosemide

Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Investigational
Matched Description: … Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …

Clofenamide

Experimental
Matched Categories: … clofenamide and potassium …

Mebutizide

Experimental
Matched Categories: … mebutizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Calcium

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... Calcium gluconate and calcium lactate are absorbed well by pregnant women. ... Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. …
Matched Mixtures name: … Magnesium Chloride ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Calcium & Magnesium Plus Potassium & Zinc …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... multivitamins and calcium ... ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents …

Mefruside

Experimental
Matched Categories: … mefruside and potassium …
Displaying drugs 76 - 100 of 103 in total